UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 354

Sortiert nach

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Nature chemical biology, 2014-12, Vol.10 (12), p.1013

2014

Volltextzugriff (PDF)

Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM

Scientific reports, 2023-05, Vol.13 (1), p.8694-8694, Article 8694

2023

Volltextzugriff (PDF)

Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold

mAbs, 2023, Vol.15 (1), p.2175311-2175311

2023

Volltextzugriff (PDF)

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

The Journal of biological chemistry, 2015-01, Vol.290 (2), p.762-774

2015

Volltextzugriff (PDF)

Automated harvesting and processing of protein crystals through laser photoablation

Acta crystallographica. Section D, Structural biology, 2016-04, Vol.72 (4), p.454-466

2016

Volltextzugriff (PDF)

Discovery of (2S)‑8-[(3R)‑3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro‑2H‑pyrimido[1,2‑a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.376-400

2015

Volltextzugriff (PDF)

Differential Water Thermodynamics Determine PI3K-Beta/Delta Selectivity for Solvent-Exposed Ligand Modifications

Journal of chemical information and modeling, 2016-05, Vol.56 (5), p.886-894

2016

Volltextzugriff (PDF)

An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics

mAbs, 2021-01, Vol.13 (1), p.1955433-1955433

2021

Volltextzugriff (PDF)

Crystal Structure of the RNA-Dependent RNA Polymerase of Hepatitis C Virus

Proceedings of the National Academy of Sciences - PNAS, 1999-11, Vol.96 (23), p.13034-13039

1999

Volltextzugriff (PDF)

Abstract P-45: Structural Studies of Multispecific Antibody/Antigen Complexes by Cryo-EM

International journal of biomedicine, 2019-06, Vol.9 (Suppl_1), p.S37-S37

2019

Volltextzugriff (PDF)

Dengue Virus Type 1 Nonstructural Glycoprotein NS1 Is Secreted from Mammalian Cells as a Soluble Hexamer in a Glycosylation-Dependent Fashion

Journal of Virology, 1999-07, Vol.73 (7), p.6104-6110

1999

Volltextzugriff (PDF)

The Crystal Structures of Four Peptide Deformylases Bound to the Antibiotic Actinonin Reveal Two Distinct Types: A Platform for the Structure-based Design of Antibacterial Agents

Journal of molecular biology, 2002-07, Vol.320 (5), p.951-962

2002

Volltextzugriff (PDF)

Escherichia coli FolC Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-microbial Therapy

The Journal of biological chemistry, 2005-05, Vol.280 (19), p.18916-18922

2005

Volltextzugriff (PDF)

1024 Non-tumour risk factors for cutaneous melanoma relapse

European journal of cancer (1990), 2015-09, Vol.51, p.S153-S153

2015

Volltextzugriff (PDF)

Alteration mapping on drill cores using a HySpex SWIR-320m hyperspectral camera: Application to the exploration of an unconformity-related uranium deposit (Saskatchewan, Canada)

Journal of geochemical exploration, 2017-01, Vol.172, p.71-88

2017

Volltextzugriff (PDF)

Complexation of Two Proteic Insect Inhibitors to the Active Site of Chymotrypsin Suggests Decoupled Roles for Binding and Selectivity

The Journal of biological chemistry, 2001-10, Vol.276 (42), p.38893-38898

2001

Volltextzugriff (PDF)

Structure of the Sec7 domain of the Arf exchange factor ARNO

Nature (London), 1998-03, Vol.392 (6671), p.101-105

1998

Volltextzugriff (PDF)

Fast NMR Methods for Measuring in the Direct and/or Competition Mode the Dissociation Constants of Chemical Fragments Interacting with a Receptor

ChemMedChem, 2019-06, Vol.14 (11), p.1115-1127

2019

Volltextzugriff (PDF)

Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex

Journal of structural biology, 2024-06, Vol.216 (2), p.108095-108095, Article 108095

2024

Volltextzugriff (PDF)

N-terminal arm exchange is observed in the 2.15 Å crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa

Structure (London), 1997-09, Vol.5 (9), p.1157-1171

1997

Volltextzugriff (PDF)

Molecular Shape and Medicinal Chemistry: A Perspective

Journal of medicinal chemistry, 2010-05, Vol.53 (10), p.3862-3886

2010

Volltextzugriff (PDF)

Discovery of 6‑(2,4-Dichlorophenyl)-5-[4-[(3S)‑1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro‑7H‑benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.512-528

2020

Volltextzugriff (PDF)

Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3 S )-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7 H -benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.512-528

2020

Volltextzugriff (PDF)

The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism

Journal of molecular biology, 1997-10, Vol.273 (3), p.714-728

1997

Volltextzugriff (PDF)

Discovery of (2 S )-8-[(3 R )-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2 H -pyrimido[1,2- a ]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.376-400

2015

Volltextzugriff (PDF)

1 – 25 von 354

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(321)
Mit Volltextzugriff
(336)

Publikationsform

1 weiteren anzeigen...

Weniger anzeigen...

Sprache

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(6)
... seit 90 Tagen
(7)

Menü

Weitere Dienste

Einstellungen

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Structural insights into the bi-specific cross-over dual variable antibody architecture by cryo-EM

Deciphering cross-species reactivity of LAMP-1 antibodies using deep mutational epitope mapping and AlphaFold

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Automated harvesting and processing of protein crystals through laser photoablation

Discovery of (2S)‑8-[(3R)‑3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro‑2H‑pyrimido[1,2‑a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Differential Water Thermodynamics Determine PI3K-Beta/Delta Selectivity for Solvent-Exposed Ligand Modifications

An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics

Crystal Structure of the RNA-Dependent RNA Polymerase of Hepatitis C Virus

Abstract P-45: Structural Studies of Multispecific Antibody/Antigen Complexes by Cryo-EM

Dengue Virus Type 1 Nonstructural Glycoprotein NS1 Is Secreted from Mammalian Cells as a Soluble Hexamer in a Glycosylation-Dependent Fashion

The Crystal Structures of Four Peptide Deformylases Bound to the Antibiotic Actinonin Reveal Two Distinct Types: A Platform for the Structure-based Design of Antibacterial Agents

Escherichia coli FolC Structure Reveals an Unexpected Dihydrofolate Binding Site Providing an Attractive Target for Anti-microbial Therapy

1024 Non-tumour risk factors for cutaneous melanoma relapse

Alteration mapping on drill cores using a HySpex SWIR-320m hyperspectral camera: Application to the exploration of an unconformity-related uranium deposit (Saskatchewan, Canada)

Complexation of Two Proteic Insect Inhibitors to the Active Site of Chymotrypsin Suggests Decoupled Roles for Binding and Selectivity

Structure of the Sec7 domain of the Arf exchange factor ARNO

Fast NMR Methods for Measuring in the Direct and/or Competition Mode the Dissociation Constants of Chemical Fragments Interacting with a Receptor

Structure and conformational variability of the HER2-trastuzumab-pertuzumab complex

N-terminal arm exchange is observed in the 2.15 Å crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa

Molecular Shape and Medicinal Chemistry: A Perspective

Discovery of 6‑(2,4-Dichlorophenyl)-5-[4-[(3S)‑1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro‑7H‑benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3 S )-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7 H -benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism

Discovery of (2 S )-8-[(3 R )-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2 H -pyrimido[1,2- a ]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid Tumors

Suchergebnisse filtern