UB Paderborn / Katalog / Suche / in CDI

Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers

Cancer discovery, 2018-06, Vol.8 (6), p.686-695

2018

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Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study

Clinical therapeutics, 2020-08, Vol.42 (8), p.1519-1534.e33

2020

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Inhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of Rosuvastatin

Drug metabolism and disposition, 2017-01, Vol.45 (1), p.27-34

2017

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A Phase I, First‐in‐Human Study of GSK2849330, an Anti‐HER3 Monoclonal Antibody, in HER3‐Expressing Solid Tumors

The oncologist (Dayton, Ohio), 2021-10, Vol.26 (10), p.e1844-e1853

2021

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Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice

PloS one, 2017-04, Vol.12 (4), p.e0176075-e0176075

2017

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Manufacturing‐dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development

Clinical and translational science, 2022-11, Vol.15 (11), p.2625-2639

2022

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Pharmacokinetic and Pharmacodynamic Implications of P-glycoprotein Modulation

Pharmacotherapy, 2001-07, Vol.21 (7), p.778-796

2001

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An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation

Bone (New York, N.Y.), 2010-02, Vol.46 (2), p.534-542

2010

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Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues

Drug metabolism and disposition, 2004-09, Vol.32 (9), p.1008

2004

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Assembling a Career: Labor Market Outcomes for Manufacturing Program Students in Two-Year Technical Colleges

Community college review, 2015-10, Vol.43 (4), p.380-406

2015

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Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification

Osteoarthritis and cartilage, 2015-08, Vol.23 (8), p.1254-1266

2015

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A framework and strategies for advancing change and innovation in two-year colleges

New directions for community colleges, 2012-03, Vol.2012 (157), p.111-124

2012

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CAN-2409 plus prodrug with standard of care immune checkpoint inhibitor for patients with stage III/IV NSCLC

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.TPS9162-TPS9162

2023

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First report of safety/tolerability and preliminary antitumor activity of CAN-2409 in inadequate responders to immune checkpoint inhibitors for stage III/IV NSCLC

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.9037-9037

2022

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CTIM-09. ENRICHED TCR/BCR VDJ REARRANGEMENTS CORRELATE WITH MRI AND SURVIVAL OUTCOMES IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA TREATED WITH CAN-3110

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii61-vii61

2022

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Synergy of TLR4 agonist GSK1795091, an innate immune activator, with agonistic antibody against co-stimulatory immune checkpoint molecule OX40 in cancer immunotherapy

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.12055-12055

2018

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Abstract 1192: Preclinical evaluation of HER3 mutations and rational combinations with AKT inhibition in enhancing anti-tumor activity of HER3 inhibition in gastric cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1192-1192

2016

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Optimizing the in vitro and clinical assessment of drug interaction risk by understanding co-medications in patient populations

Expert opinion on drug metabolism & toxicology, 2013-06, Vol.9 (6), p.737-751

2013

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Pharmacokinetics of flunisolide administered via metered dose inhaler with and without a spacer device and following oral administration

Annals of allergy, asthma, & immunology, 2000-05, Vol.84 (5), p.528-532

2000

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Development of an ultra-sensitive assay for the determination of an aminoalkyl glucosaminide 4-phosphate, GSK1795091, in plasma to support a first time in human study

Analytical methods, 2018-01, Vol.1 (25), p.374-38

2018

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Evidence for reversible sequestration of morphine in rat liver

Biochemical pharmacology, 1996-08, Vol.52 (4), p.535-541

1996

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Economic Returns to Sub-Baccalaureate Technical Education: A Study of Labor Market Outcomes for Manufacturing Engineering Technologist and Technician Education (METTE) Programs in the Wisconsin Technical College System

ProQuest LLC, 2013, p.130

Matheny, Christopher J

2013

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ProQuest

A Pilot Study of Estrogen's Effects on Bronchial Myocyte Adhesion Molecule Expression

Pharmacotherapy, 1999-12, Vol.19 (12), p.1426-1431

1999

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RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (11), p.2734-2739

2018

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Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma

Stem cell reports, 2016-11, Vol.7 (5), p.983-997

2016

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Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers

Safety, Pharmacokinetics, and Pharmacodynamics of the TLR4 Agonist GSK1795091 in Healthy Individuals: Results from a Randomized, Double-blind, Placebo-controlled, Ascending Dose Study

Inhibition of Intestinal OATP2B1 by the Calcium Receptor Antagonist Ronacaleret Results in a Significant Drug-Drug Interaction by Causing a 2-Fold Decrease in Exposure of Rosuvastatin

A Phase I, First‐in‐Human Study of GSK2849330, an Anti‐HER3 Monoclonal Antibody, in HER3‐Expressing Solid Tumors

Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice

Manufacturing‐dependent change in biological activity of the TLR4 agonist GSK1795091 and implications for lipid A analog development

Pharmacokinetic and Pharmacodynamic Implications of P-glycoprotein Modulation

An orally active calcium-sensing receptor antagonist that transiently increases plasma concentrations of PTH and stimulates bone formation

Effect of prototypical inducing agents on P-glycoprotein and CYP3A expression in mouse tissues

Assembling a Career: Labor Market Outcomes for Manufacturing Program Students in Two-Year Technical Colleges

Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification

A framework and strategies for advancing change and innovation in two-year colleges

CAN-2409 plus prodrug with standard of care immune checkpoint inhibitor for patients with stage III/IV NSCLC

First report of safety/tolerability and preliminary antitumor activity of CAN-2409 in inadequate responders to immune checkpoint inhibitors for stage III/IV NSCLC

CTIM-09. ENRICHED TCR/BCR VDJ REARRANGEMENTS CORRELATE WITH MRI AND SURVIVAL OUTCOMES IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA TREATED WITH CAN-3110

Synergy of TLR4 agonist GSK1795091, an innate immune activator, with agonistic antibody against co-stimulatory immune checkpoint molecule OX40 in cancer immunotherapy

Abstract 1192: Preclinical evaluation of HER3 mutations and rational combinations with AKT inhibition in enhancing anti-tumor activity of HER3 inhibition in gastric cancer

Optimizing the in vitro and clinical assessment of drug interaction risk by understanding co-medications in patient populations

Pharmacokinetics of flunisolide administered via metered dose inhaler with and without a spacer device and following oral administration

Development of an ultra-sensitive assay for the determination of an aminoalkyl glucosaminide 4-phosphate, GSK1795091, in plasma to support a first time in human study

Evidence for reversible sequestration of morphine in rat liver

Economic Returns to Sub-Baccalaureate Technical Education: A Study of Labor Market Outcomes for Manufacturing Engineering Technologist and Technician Education (METTE) Programs in the Wisconsin Technical College System

A Pilot Study of Estrogen's Effects on Bronchial Myocyte Adhesion Molecule Expression

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma

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