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Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory

The EMBO journal, 2017-09, Vol.36 (18), p.2770-2789

2017

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Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease

Naunyn-Schmiedeberg's archives of pharmacology, 2021-12, Vol.394 (12), p.2363-2379

2021

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The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13226

2023

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Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4

Nature Immunology, 2007-03, Vol.8 (3), p.312-320

2007

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Assessing the Use of the sGC Stimulator BAY-747, as a Potential Treatment for Duchenne Muscular Dystrophy

International journal of molecular sciences, 2021-08, Vol.22 (15), p.8016

2021

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Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice

The Journal of clinical investigation, 2010-09, Vol.120 (9), p.3267-3279

2010

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Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels

Cellular physiology and biochemistry, 2020-11, Vol.54 (6), p.1115-1131

2020

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Nitric Oxide–Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease

American journal of respiratory cell and molecular biology, 2018-05, Vol.58 (5), p.636-647

2018

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TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation

Molecular metabolism (Germany), 2018-03, Vol.9, p.156-167

2018

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Loss of smooth muscle CYB5R3 amplifies angiotensin-II induced hypertension by increasing sGC heme oxidation

JCI insight, 2019-10, Vol.4 (19)

2019

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New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions

European journal of applied physiology, 2018-01, Vol.118 (1), p.195-203

2018

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Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage

American journal of nephrology, 2021-10, Vol.52 (8), p.642-652

2021

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Combined Efficacy of the Novel Nonsteroidal and Selective Mineralocorticoid Receptor Antagonist Finerenone and the SGLT2 Inhibitor Empagliflozin in a Non-Diabetic Cardiorenal Rat Model: PO0642

Journal of the American Society of Nephrology, 2020-10, Vol.31 (10S), p.243-243

2020

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The Renoprotective Effects of the Soluble Guanylate Cyclase (sGC) Activator Runcaciguat Are Associated with Distinct Changes in Renal Gene Expression Profiles: PO0708

Journal of the American Society of Nephrology, 2021-10, Vol.32 (10S), p.252-253

2021

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Urinary miRNA Profiles in Chronic Kidney Injury-Benefits of Extracellular Vesicle Enrichment and miRNAs as Potential Biomarkers for Renal Fibrosis, Glomerular Injury, and Endothelial Dysfunction

Toxicological sciences, 2022-04, Vol.187 (1), p.35-50

2022

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The Novel Soluble Guanylyl Cyclase (sGC) Activator Runcaciguat Improves Cardiorenal Morbidity in a Diabetic Rat Model of CKD: PO0917

Journal of the American Society of Nephrology, 2020-10, Vol.31 (10S), p.318-318

2020

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Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice

Journal of molecular and cellular cardiology, 2014-09, Vol.74, p.307-317

2014

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TRPM4

Handbook of experimental pharmacology, 2014, Vol.222, p.461

2014

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Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice

Journal of visualized experiments, 2015-09 (103)

2015

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Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells

Nature cell biology, 2008-12, Vol.10 (12), p.1421-1430

2008

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A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

European heart journal, 2015-09, Vol.36 (33), p.2257-2266

2015

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Increased β-adrenergic inotropy in ventricular myocardium from Trpm4-/- mice

Circulation research, 2014-01, Vol.114 (2), p.283-294

2014

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TRPM4-mediated control of FcεRI-evoked Ca2+ elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells

Scientific reports, 2016-09, Vol.6 (1), Article 32981

2016

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TRPM4-mediated control of FcεRI-evoked Ca(2+) elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells

Scientific reports, 2016-09, Vol.6, p.32981

2016

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Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory

Runcaciguat, a novel soluble guanylate cyclase activator, shows renoprotection in hypertensive, diabetic, and metabolic preclinical models of chronic kidney disease

The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats

Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4

Assessing the Use of the sGC Stimulator BAY-747, as a Potential Treatment for Duchenne Muscular Dystrophy

Increased catecholamine secretion contributes to hypertension in TRPM4-deficient mice

Control of Insulin Release by Transient Receptor Potential Melastatin 3 (TRPM3) Ion Channels

Nitric Oxide–Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease

TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation

Loss of smooth muscle CYB5R3 amplifies angiotensin-II induced hypertension by increasing sGC heme oxidation

New pulmonary hypertension model in conscious dogs to investigate pulmonary-selectivity of acute pharmacological interventions

Effects of Finerenone Combined with Empagliflozin in a Model of Hypertension-Induced End-Organ Damage

Combined Efficacy of the Novel Nonsteroidal and Selective Mineralocorticoid Receptor Antagonist Finerenone and the SGLT2 Inhibitor Empagliflozin in a Non-Diabetic Cardiorenal Rat Model: PO0642

The Renoprotective Effects of the Soluble Guanylate Cyclase (sGC) Activator Runcaciguat Are Associated with Distinct Changes in Renal Gene Expression Profiles: PO0708

Urinary miRNA Profiles in Chronic Kidney Injury-Benefits of Extracellular Vesicle Enrichment and miRNAs as Potential Biomarkers for Renal Fibrosis, Glomerular Injury, and Endothelial Dysfunction

The Novel Soluble Guanylyl Cyclase (sGC) Activator Runcaciguat Improves Cardiorenal Morbidity in a Diabetic Rat Model of CKD: PO0917

Adenylyl cyclase-mediated effects contribute to increased Isoprenaline-induced cardiac contractility in TRPM4-deficient mice

TRPM4

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice

Transient receptor potential M3 channels are ionotropic steroid receptors in pancreatic β cells

A background Ca2+ entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

Increased β-adrenergic inotropy in ventricular myocardium from Trpm4-/- mice

TRPM4-mediated control of FcεRI-evoked Ca2+ elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells

TRPM4-mediated control of FcεRI-evoked Ca(2+) elevation comprises enhanced plasmalemmal trafficking of TRPM4 channels in connective tissue type mast cells

TRPC5 controls the adrenaline-mediated counter regulation of hypoglycemia

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