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Heteroaromatic Analogs of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as High-Affinity Dopamine Reuptake Inhibitors

Journal of medicinal chemistry, 1997-02, Vol.40 (5), p.705-716

1997

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Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

Journal of acquired immune deficiency syndromes (1999), 2004-05, Vol.36 (1), p.541

2004

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DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods

Bioorganic & medicinal chemistry, 2007-01, Vol.15 (2), p.1146-1159

2007

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Oxygenated Analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as Potential Extended-Action Cocaine-Abuse Therapeutic Agents

Journal of medicinal chemistry, 1999-12, Vol.42 (24), p.5029-5042

1999

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Asp147 in the third transmembrane helix of the rat μ opioid receptor forms ion-pairing with morphine and naltrexone

Life sciences (1973), 1999, Vol.65 (2), p.175-185

1999

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Sustained Decrease in Cocaine-Maintained Responding in Rhesus Monkeys with 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]- 4-(3-hydroxy-3-phenylpropyl)piperazinyl Decanoate, a Long-Acting Ester Derivative of GBR 12909

Journal of medicinal chemistry, 1996-11, Vol.39 (24), p.4689-4691

1996

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Doses of GBR12909 that suppress cocaine self-administration in non-human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 PET scans

Synapse (New York, N.Y.), 1999-04, Vol.32 (1), p.44-50

1999

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GBR12909 attenuates amphetamine-induced striatal dopamine release as measured by [11C]raclopride continuous infusion PET scans

Synapse (New York, N.Y.), 1999-09, Vol.33 (4), p.268-273

1999

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Development of Novel, Potent, and Selective Dopamine Reuptake Inhibitors through Alteration of the Piperazine Ring of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909)

Journal of medicinal chemistry, 1996-11, Vol.39 (24), p.4704-4716

1996

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Phentermine/fenfluramine decreases cocaine self-administration in rhesus monkeys

Neuroreport, 1997-04, Vol.8 (6), p.1347-1351

1997

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Effects of Dopamine Reuptake Inhibitors on Food-and Cocaine-Maintained Responding: I. Dependence on Unit Dose of Cocaine

Experimental and clinical psychopharmacology, 1995-08, Vol.3 (3), p.219-231

1995

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Effects of Dopamine Reuptake Inhibitors on Food-and Cocaine-Maintained Responding: II. Comparisons With Other Drugs and Repeated Administrations

Experimental and clinical psychopharmacology, 1995-08, Vol.3 (3), p.232-239

1995

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Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate

Synapse (New York, N.Y.), 1998-04, Vol.28 (4), p.322-338

1998

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Pharmacologic actions of subtype-selective and novel GABAergic ligands in rat lines with differential sensitivity to ethanol

Pharmacology, biochemistry and behavior, 1996-03, Vol.53 (3), p.723-730

1996

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Opioid Peptide Receptor Studies. 8. One of the Mouse Brain δ NCX Binding Sites is Similar to the Cloned Mouse Opioid δ Receptor: Further Evidence for Heterogeneity of δ Opioid Receptors

Peptides (New York, N.Y. : 1980), 1998-02, Vol.19 (2), p.343-350

1998

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Opioid peptide receptor studies. 9. Identification of a novel non-μ- non-δ-like opioid peptide binding site in rat brain

Peptides (New York, N.Y. : 1980), 1998-01, Vol.19 (6), p.1079-1090

1998

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A Study of the Effect of Catalyst on Stereochemistry in the Hydrogenation of N-(Menthyloxycarbonyl)-N-Methyl-2-(N-Pyrrolidinyl)-1-cyclohexenamine

Synthetic communications, 1994-06, Vol.24 (11), p.1531-1540

1994

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Synthesis of secoisoquinoline alkaloids. Total synthesis of (±)-corydalisol (±)-aobamine and (±)-hypecorinine

Tetrahedron, 1988, Vol.44 (4), p.1221-1226

1988

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Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes

Regulatory peptides, 1995-10, Vol.59 (2), p.247-253

1995

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Synthesis of isoquinoline alkaloids. Total synthesis of (±)-tetrahydroescholamine and its (±)-threo- and (±)-erythro-α-hydroxy analogs

Liebigs Annalen der Chemie, 1991-01, Vol.1991 (1), p.73-75

1991

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(+)-decumbensine and (+)-epi-α-decumbensine are not α-hydroxybenzyltetrahydroisoquinolines

Tetrahedron letters, 1989, Vol.30 (45), p.6215-6218

1989

Volltextzugriff (PDF)

Synthetic and stereochemical studies on phthalideisoquinoline hemiacetals

Liebigs Annalen der Chemie, 1991-03, Vol.1991 (3), p.287-289

1991

Volltextzugriff (PDF)

Synthesis of [ 123 I] tert ‐butyl 8‐iodo‐5,6‐dihydro‐5‐methyl‐6‐oxo‐4 H ‐imidazo[1,5‐a][1,4]benzodiazepine 3‐carboxylate, a potential SPECT imaging agent for diazepam‐insensitive (DI) benzodiazepine receptors

Journal of labelled compounds & radiopharmaceuticals, 1994-01, Vol.34 (1), p.27-32

1994

Volltextzugriff (PDF)

Synthesis of [123I]tert-butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a potential SPECT imaging agent for diazepam-insensitive (DI) benzodiazepine receptors

Journal of labelled compounds & radiopharmaceuticals, 1994-01, Vol.34 (1), p.27-32

1994

Volltextzugriff (PDF)

Impact of umbilical cord arterial pH, gestational age, and birth weight on neurodevelopmental outcomes for preterm neonates

PeerJ (San Francisco, CA), 2021-09, Vol.9, p.e12043-e12043, Article e12043

2021

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Heteroaromatic Analogs of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as High-Affinity Dopamine Reuptake Inhibitors

Recommendations for the nonclinical development of topical microbicides for prevention of HIV transmission: an update

DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods

Oxygenated Analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as Potential Extended-Action Cocaine-Abuse Therapeutic Agents

Asp147 in the third transmembrane helix of the rat μ opioid receptor forms ion-pairing with morphine and naltrexone

Sustained Decrease in Cocaine-Maintained Responding in Rhesus Monkeys with 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]- 4-(3-hydroxy-3-phenylpropyl)piperazinyl Decanoate, a Long-Acting Ester Derivative of GBR 12909

Doses of GBR12909 that suppress cocaine self-administration in non-human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 PET scans

GBR12909 attenuates amphetamine-induced striatal dopamine release as measured by [11C]raclopride continuous infusion PET scans

Development of Novel, Potent, and Selective Dopamine Reuptake Inhibitors through Alteration of the Piperazine Ring of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909)

Phentermine/fenfluramine decreases cocaine self-administration in rhesus monkeys

Effects of Dopamine Reuptake Inhibitors on Food-and Cocaine-Maintained Responding: I. Dependence on Unit Dose of Cocaine

Effects of Dopamine Reuptake Inhibitors on Food-and Cocaine-Maintained Responding: II. Comparisons With Other Drugs and Repeated Administrations

Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate

Pharmacologic actions of subtype-selective and novel GABAergic ligands in rat lines with differential sensitivity to ethanol

Opioid Peptide Receptor Studies. 8. One of the Mouse Brain δ NCX Binding Sites is Similar to the Cloned Mouse Opioid δ Receptor: Further Evidence for Heterogeneity of δ Opioid Receptors

Opioid peptide receptor studies. 9. Identification of a novel non-μ- non-δ-like opioid peptide binding site in rat brain

A Study of the Effect of Catalyst on Stereochemistry in the Hydrogenation of N-(Menthyloxycarbonyl)-N-Methyl-2-(N-Pyrrolidinyl)-1-cyclohexenamine

Synthesis of secoisoquinoline alkaloids. Total synthesis of (±)-corydalisol (±)-aobamine and (±)-hypecorinine

Opioid peptide receptor studies. 4. Antisense oligodeoxynucleotide to the delta opioid receptor delineates opioid receptor subtypes

Synthesis of isoquinoline alkaloids. Total synthesis of (±)-tetrahydroescholamine and its (±)-threo- and (±)-erythro-α-hydroxy analogs

(+)-decumbensine and (+)-epi-α-decumbensine are not α-hydroxybenzyltetrahydroisoquinolines

Synthetic and stereochemical studies on phthalideisoquinoline hemiacetals

Synthesis of [ 123 I] tert ‐butyl 8‐iodo‐5,6‐dihydro‐5‐methyl‐6‐oxo‐4 H ‐imidazo[1,5‐a][1,4]benzodiazepine 3‐carboxylate, a potential SPECT imaging agent for diazepam‐insensitive (DI) benzodiazepine receptors

Synthesis of [123I]tert-butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine 3-carboxylate, a potential SPECT imaging agent for diazepam-insensitive (DI) benzodiazepine receptors

Impact of umbilical cord arterial pH, gestational age, and birth weight on neurodevelopmental outcomes for preterm neonates

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