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Phosphorylation of endogenous α-synuclein induced by extracellular seeds initiates at the pre-synaptic region and spreads to the cell body

Scientific reports, 2022-01, Vol.12 (1), p.1163-1163, Article 1163

2022

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Molecular mechanisms of the co‐deposition of multiple pathological proteins in neurodegenerative diseases

Neuropathology, 2018-02, Vol.38 (1), p.64-71

2018

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Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders

Pharmacology & therapeutics (Oxford), 2017-04, Vol.172, p.22-33

2017

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Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains

Cell reports (Cambridge), 2013-07, Vol.4 (1), p.124-134

2013

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Progression of phosphorylated α‐synuclein in Macaca fuscata

Brain pathology (Zurich, Switzerland), 2021-09, Vol.31 (5), p.e12952-n/a

2021

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Ubiquitination of alpha-synuclein filaments by Nedd4 ligases

PloS one, 2018-07, Vol.13 (7), p.e0200763

2018

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Pathological alpha-synuclein propagates through neural networks

Acta neuropathologica communications, 2014-08, Vol.2 (1), p.88, Article 88

2014

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Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms

Brain (London, England : 1878), 2022-03, Vol.145 (1), p.349-361

2022

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Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice

PloS one, 2012-12, Vol.7 (12), p.e52389

2012

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C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43

Human molecular genetics, 2018-08, Vol.27 (15), p.2658-2670

2018

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Cerebellar neuronal loss in amyotrophic lateral sclerosis cases with ATXN2 intermediate repeat expansions

Annals of neurology, 2016-02, Vol.79 (2), p.295-305

2016

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Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene

Neuropathology and applied neurobiology, 2015-08, Vol.41 (5), p.601-612

2015

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Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice

Acta neuropathologica communications, 2019-09, Vol.7 (1), p.148-11, Article 148

2019

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Isomerase Pin1 Stimulates Dephosphorylation of Tau Protein at Cyclin-dependent Kinase (Cdk5)-dependent Alzheimer Phosphorylation Sites

The Journal of biological chemistry, 2013-03, Vol.288 (11), p.7968-7977

2013

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Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds

Acta neuropathologica communications, 2021-11, Vol.9 (1), p.189-15, Article 189

2021

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The Abundance of Nonphosphorylated Tau in Mouse and Human Tauopathy Brains Revealed by the Use of Phos-Tag Method

The American journal of pathology, 2016-02, Vol.186 (2), p.398-409

2016

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Differential diagnosis of amyotrophic lateral sclerosis from Guillain-Barré syndrome by quantitative determination of TDP-43 in cerebrospinal fluid

International journal of neuroscience, 2014-05, Vol.124 (5), p.344-349

2014

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Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

Biochemical and biophysical research communications, 2012-01, Vol.417 (1), p.116-121

2012

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Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration

Brain (London, England : 1878), 2017-02, Vol.140 (2), p.266-278

2017

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Prion-like Propagation of Pathological α-Synuclein in Vivo

YAKUGAKU ZASSHI, 2019/07/01, Vol.139(7), pp.1007-1013

2019

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C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS

Neuropathology and applied neurobiology, 2014-10, Vol.40 (6), p.783-788

2014

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Prion-like spreading of pathological α-synuclein in brain

Brain (London, England : 1878), 2013-04, Vol.136 (Pt 4), p.1128-1138

2013

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C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43

Human molecular genetics, 2018-08, Vol.27 (15), p.2658-2670

2018

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Prion-like Propagation of Pathological α-Synuclein in Vivo

Yakugaku zasshi, 2019-07, Vol.139 (7), p.1007-1013

2019

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αシヌクレイン脳内伝播の動物モデル

日本薬理学雑誌, 2019, Vol.154(6), pp.301-305

鈴掛, 雅美

2019

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Phosphorylation of endogenous α-synuclein induced by extracellular seeds initiates at the pre-synaptic region and spreads to the cell body

Molecular mechanisms of the co‐deposition of multiple pathological proteins in neurodegenerative diseases

Prion-like mechanisms and potential therapeutic targets in neurodegenerative disorders

Prion-like Properties of Pathological TDP-43 Aggregates from Diseased Brains

Progression of phosphorylated α‐synuclein in Macaca fuscata

Ubiquitination of alpha-synuclein filaments by Nedd4 ligases

Pathological alpha-synuclein propagates through neural networks

Development of a novel tau propagation mouse model endogenously expressing 3 and 4 repeat tau isoforms

Methylene blue reduced abnormal tau accumulation in P301L tau transgenic mice

C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43

Cerebellar neuronal loss in amyotrophic lateral sclerosis cases with ATXN2 intermediate repeat expansions

Accumulation of dipeptide repeat proteins predates that of TDP-43 in frontotemporal lobar degeneration associated with hexanucleotide repeat expansions in C9ORF72 gene

Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice

Isomerase Pin1 Stimulates Dephosphorylation of Tau Protein at Cyclin-dependent Kinase (Cdk5)-dependent Alzheimer Phosphorylation Sites

Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds

The Abundance of Nonphosphorylated Tau in Mouse and Human Tauopathy Brains Revealed by the Use of Phos-Tag Method

Differential diagnosis of amyotrophic lateral sclerosis from Guillain-Barré syndrome by quantitative determination of TDP-43 in cerebrospinal fluid

Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration

Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration

Prion-like Propagation of Pathological α-Synuclein in Vivo

C9ORF72 repeat-associated non-ATG-translated polypeptides are distributed independently of TDP-43 in a Japanese patient with c9ALS

Prion-like spreading of pathological α-synuclein in brain

C9ORF72 dipeptide repeat poly-GA inclusions promote intracellular aggregation of phosphorylated TDP-43

Prion-like Propagation of Pathological α-Synuclein in Vivo

αシヌクレイン脳内伝播の動物モデル

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