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Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability

Bioorganic & medicinal chemistry letters, 2011-10, Vol.21 (19), p.5684-5687

2011

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Optimisation of a novel series of selective CNS penetrant CB₂ agonists

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4284-4287

2011

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An in situ oxidation strategy towards overcoming hERG affinity

Bioorganic & medicinal chemistry letters, 2010-11, Vol.20 (22), p.6400-6404

2010

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Solid-phase synthesis of an arylsulfone hydroxamate library

Bioorganic & medicinal chemistry letters, 2000-08, Vol.10 (15), p.1637-1640

2000

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The design and discovery of novel amide CCR5 antagonists

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1084-1088

2009

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Substituted Pyrazolopyridines as Potent and Selective PDE5 Inhibitors: Potential Agents for Treatment of Erectile Dysfunction

Journal of medicinal chemistry, 2001-03, Vol.44 (7), p.1025-1027

2001

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Parallel Synthesis of Aldehydes and Ketone Facilitated by a New Solid-Phase Weinreb Amide

Journal of organic chemistry, 1999-03, Vol.64 (6), p.1823-1830

1999

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Synthesis of fused pyridopyrrolidine dione derivatives using hetero Diels–Alder reactions

Tetrahedron letters, 2001-12, Vol.42 (51), p.8931-8934

2001

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A mild and efficient method for aromatic chlorination of electron-rich arylalkyl amines

Tetrahedron letters, 2001-05, Vol.42 (19), p.3247-3249

2001

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Mono-Chlorination of Electron-Rich Arylalkyl- and Heteroarylalkyl-amines and Amino Acids Using Sulfuryl Chloride

Synthesis (Stuttgart), 2003, Vol.2003 (3), p.403-407

2003

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A concise synthesis of chiral indanes as α1A adrenoceptor partial agonists

Tetrahedron letters, 2015-11, Vol.56 (47), p.6546-6550

2015

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A concise synthesis of chiral indanes as α 1A adrenoceptor partial agonists

Tetrahedron letters, 2015-11, Vol.56 (47), p.6546-6550

2015

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A Convenient Synthesis of Highly Substituted 3- N , N -Dialkylamino-1,2,4-triazoles

Synlett, 2008-10, Vol.2008 (16), p.2421-2424

2008

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Optimisation of a novel series of selective CNS penetrant CB sub(2 agonists)

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4284-4287

2011

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Optimisation of a novel series of selective CNS penetrant CB 2 agonists

Bioorganic & medicinal chemistry letters, 2011, Vol.21 (14), p.4284-4287

2011

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Optimisation of a novel series of selective CNS penetrant CB(2) agonists

Bioorganic & medicinal chemistry letters, 2011-07, Vol.21 (14), p.4284-4287

2011

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Sulfonamidopyrrolidinone Factor Xa Inhibitors: Potency and Selectivity Enhancements via P-1 and P-4 Optimization

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3572-3587

1999

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Biodegradable stent or balloon dilatation for benign oesophageal stricture: Pilot randomised controlled trial

World journal of gastroenterology : WJG, 2014-12, Vol.20 (48), p.18199-18206

2014

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Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (18), p.2753-2758

1999

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ChemInform Abstract: A Convenient Synthesis of Highly Substituted 3-N,N-Dialkylamino-1,2,4-triazoles

ChemInform, 2009-02, Vol.40 (5), p.no-no

2009

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ChemInform Abstract: Synthesis of Fused Pyridopyrrolidine Dione Derivatives Using Hetero Diels-Alder Reactions

ChemInform, 2002-03, Vol.33 (10), p.no-no

2002

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ChemInform Abstract: A Mild and Efficient Method for Aromatic Chlorination of Electron-Rich Arylalkyl Amines

ChemInform, 2001-07, Vol.32 (30), p.no-no

2001

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Monochlorination of Electron-Rich Arylalkyl- and Heteroarylalkyl-Amines and Amino Acids Using Sulfuryl Chloride

ChemInform, 2003-07, Vol.34 (26), p.no-no

2003

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Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

The New England journal of medicine, 2023-04, Vol.388 (17), p.1547-1558

2023

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An Imidazopiperidine Series of CCR5 Antagonists for the Treatment of HIV: The Discovery of N-{(1S)-1-(3-Fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798)

Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability

Optimisation of a novel series of selective CNS penetrant CB₂ agonists

An in situ oxidation strategy towards overcoming hERG affinity

Solid-phase synthesis of an arylsulfone hydroxamate library

The design and discovery of novel amide CCR5 antagonists

Substituted Pyrazolopyridines as Potent and Selective PDE5 Inhibitors: Potential Agents for Treatment of Erectile Dysfunction

Parallel Synthesis of Aldehydes and Ketone Facilitated by a New Solid-Phase Weinreb Amide

Synthesis of fused pyridopyrrolidine dione derivatives using hetero Diels–Alder reactions

A mild and efficient method for aromatic chlorination of electron-rich arylalkyl amines

Mono-Chlorination of Electron-Rich Arylalkyl- and Heteroarylalkyl-amines and Amino Acids Using Sulfuryl Chloride

A concise synthesis of chiral indanes as α1A adrenoceptor partial agonists

A concise synthesis of chiral indanes as α 1A adrenoceptor partial agonists

A Convenient Synthesis of Highly Substituted 3- N , N -Dialkylamino-1,2,4-triazoles

Optimisation of a novel series of selective CNS penetrant CB sub(2 agonists)

Optimisation of a novel series of selective CNS penetrant CB 2 agonists

Optimisation of a novel series of selective CNS penetrant CB(2) agonists

Sulfonamidopyrrolidinone Factor Xa Inhibitors: Potency and Selectivity Enhancements via P-1 and P-4 Optimization

Biodegradable stent or balloon dilatation for benign oesophageal stricture: Pilot randomised controlled trial

Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors

ChemInform Abstract: A Convenient Synthesis of Highly Substituted 3-N,N-Dialkylamino-1,2,4-triazoles

ChemInform Abstract: Synthesis of Fused Pyridopyrrolidine Dione Derivatives Using Hetero Diels-Alder Reactions

ChemInform Abstract: A Mild and Efficient Method for Aromatic Chlorination of Electron-Rich Arylalkyl Amines

Monochlorination of Electron-Rich Arylalkyl- and Heteroarylalkyl-Amines and Amino Acids Using Sulfuryl Chloride

Fifteen-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer

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