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Heterobivalent ligands target cell-surface receptor combinations in vivo

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21295-21300

2012

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Deoxycholic Acid Induces Intracellular Signaling through Membrane Perturbations

The Journal of biological chemistry, 2006-05, Vol.281 (21), p.14948-14960

2006

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Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor

Molecular cancer therapeutics, 2010-03, Vol.9 (3), p.706-717

2010

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Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors

Angewandte Chemie (International ed.), 2008-01, Vol.47 (9), p.1685-1688

2008

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Enhanced targeting with heterobivalent ligands

Molecular cancer therapeutics, 2009-08, Vol.8 (8), p.2356-2365

2009

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Synthesis of Conformationally Constrained Diaminodicarboxylic Acid Derivatives

Journal of organic chemistry, 2009-11, Vol.74 (22), p.8773-8778

2009

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Substrate-dependent ligand inhibition of the human organic cation transporter OCT2

The Journal of pharmacology and experimental therapeutics, 2013-08, Vol.346 (2), p.300

2013

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Recent development of anticancer therapeutics targeting Akt

Recent patents on anti-cancer drug discovery, 2011-01, Vol.6 (1), p.146

2011

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Discovery of a novel class of AKT pleckstrin homology domain inhibitors

Molecular cancer therapeutics, 2008-09, Vol.7 (9), p.2621-2632

2008

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Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors

Bioorganic & medicinal chemistry, 2013-09, Vol.21 (17), p.5029-5038

2013

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Covalent binding with model quinone compounds unveils the environmental fate of the insensitive munitions reduced product 2,4-diaminoanisole (DAAN) under anoxic conditions

Journal of hazardous materials, 2021-07, Vol.413, p.125459, Article 125459

2021

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pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1)

PloS one, 2014, Vol.9 (1), p.e85796

2014

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Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model

Translational oncology, 2016-06, Vol.9 (3), p.228-235

2016

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Covalent bonding of aromatic amine daughter products of 2,4-dinitroanisole (DNAN) with model quinone compounds representing humus via nucleophilic addition

Environmental pollution (1987), 2021-01, Vol.268 (Pt B), p.115862, Article 115862

2021

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Palladium-catalyzed hydrogenations in dichloromethane

Synthetic communications, 2022-09, Vol.52 (18), p.1825-1833

2022

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Conformational analysis of bridgehead-substituted bicyclo[ m. m. m]alkanes and bicyclo[8.8. n]alkanes

Tetrahedron, 2009-12, Vol.65 (50), p.10317-10322

2009

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Evidence of anaerobic coupling reactions between reduced intermediates of 4-nitroanisole

Chemosphere (Oxford), 2018-03, Vol.195, p.372-380

2018

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Coupling reactions between reduced intermediates of insensitive munitions compound analog 4-nitroanisole

Chemosphere (Oxford), 2019-05, Vol.222, p.789-796

2019

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Crystal engineering with 1,4-piperazine-2,5-diones

CrystEngComm, 2014-01, Vol.16 (37), p.862-8637

Mash, Eugene A

2014

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Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors

Bioorganic & medicinal chemistry letters, 2010-04, Vol.20 (8), p.2489-2492

2010

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Solvent-free nitration of electron-rich arenes

Synthetic communications, 2017-12, Vol.47 (24), p.2395-2398

2017

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Magnetic resonance imaging of RRx-001 pharmacodynamics in preclinical tumors

Oncotarget, 2017-11, Vol.8 (60), p.102511-102520

2017

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On the synthesis of 1,4,7-tris( tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane

Tetrahedron letters, 2011-04, Vol.52 (17), p.2058-2061

2011

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Design, Synthesis, and Evaluation of 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Derived, Redox-Sensitive Contrast Agents for Magnetic Resonance Imaging

Journal of medicinal chemistry, 2010-09, Vol.53 (18), p.6747-6757

2010

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Spectrophotometric determination and removal of unchelated europium ions from solutions containing Eu-diethylenetriaminepentaacetic acid chelate–peptide conjugates

Analytical biochemistry, 2014-11, Vol.464, p.24-29

2014

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Heterobivalent ligands target cell-surface receptor combinations in vivo

Deoxycholic Acid Induces Intracellular Signaling through Membrane Perturbations

Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor

Heterobivalent Ligands Crosslink Multiple Cell-Surface Receptors: The Human Melanocortin-4 and δ-Opioid Receptors

Enhanced targeting with heterobivalent ligands

Synthesis of Conformationally Constrained Diaminodicarboxylic Acid Derivatives

Substrate-dependent ligand inhibition of the human organic cation transporter OCT2

Recent development of anticancer therapeutics targeting Akt

Discovery of a novel class of AKT pleckstrin homology domain inhibitors

Synthesis and Characterization of Time-resolved Fluorescence Probes for Evaluation of Competitive Binding to Melanocortin Receptors

Covalent binding with model quinone compounds unveils the environmental fate of the insensitive munitions reduced product 2,4-diaminoanisole (DAAN) under anoxic conditions

pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1)

Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model

Covalent bonding of aromatic amine daughter products of 2,4-dinitroanisole (DNAN) with model quinone compounds representing humus via nucleophilic addition

Palladium-catalyzed hydrogenations in dichloromethane

Conformational analysis of bridgehead-substituted bicyclo[ m. m. m]alkanes and bicyclo[8.8. n]alkanes

Evidence of anaerobic coupling reactions between reduced intermediates of 4-nitroanisole

Coupling reactions between reduced intermediates of insensitive munitions compound analog 4-nitroanisole

Crystal engineering with 1,4-piperazine-2,5-diones

Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors

Solvent-free nitration of electron-rich arenes

Magnetic resonance imaging of RRx-001 pharmacodynamics in preclinical tumors

On the synthesis of 1,4,7-tris( tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane

Design, Synthesis, and Evaluation of 1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic Acid Derived, Redox-Sensitive Contrast Agents for Magnetic Resonance Imaging

Spectrophotometric determination and removal of unchelated europium ions from solutions containing Eu-diethylenetriaminepentaacetic acid chelate–peptide conjugates

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