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Telomere dysfunction induces metabolic and mitochondrial compromise

Nature (London), 2011-02, Vol.470 (7334), p.359-365

2011

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Telomere Shortening and Mood Disorders: Preliminary Support for a Chronic Stress Model of Accelerated Aging

Biological psychiatry (1969), 2006-09, Vol.60 (5), p.432-435

2006

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Connecting Chromosomes, Crisis, and Cancer

Science (American Association for the Advancement of Science), 2002-07, Vol.297 (5581), p.565-569

2002

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Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.E2200-E2209

2014

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Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development

Diabetes (New York, N.Y.), 2018-05, Vol.67 (5), p.923-935

2018

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Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression

Genes & development, 2003-01, Vol.17 (1), p.88-100

2003

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Generating Mouse Models Using CRISPR‐Cas9‐Mediated Genome Editing

Current protocols in mouse biology, 2016-03, Vol.6 (1), p.39-66

2016

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An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

Nature genetics, 2001-04, Vol.27 (4), p.417-421

2001

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In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts

Science (American Association for the Advancement of Science), 1998-04, Vol.280 (5363), p.590-592

1998

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DNA-Dependent Protein Kinase Catalytic Subunit Is Not Required for Dysfunctional Telomere Fusion and Checkpoint Response in the Telomerase-Deficient Mouse

Molecular and Cellular Biology, 2007-03, Vol.27 (6), p.2253-2265

2007

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SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Nature (London), 2011-03, Vol.471 (7336), p.104

2011

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Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response

Pain (Amsterdam), 2019-08, Vol.160 (8), p.1740-1753

2019

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Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response

Pain (Amsterdam), 2019-08, Vol.160 (8), p.1740-1753

2019

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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

Nature (London), 2000-04, Vol.404 (6778), p.613-617

2000

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Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

Nature (London), 2003-02, Vol.421 (6923), p.643-648

2003

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The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

Cell, 1999-12, Vol.99 (6), p.577-587

1999

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The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

Cell, 1998-05, Vol.93 (3), p.477-486

1998

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hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

Molecular and Cellular Biology, 1997-10, Vol.17 (10), p.6087-6096

1997

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Alu elements mediate MYB gene tandem duplication in human T-ALL

The Journal of experimental medicine, 2007-12, Vol.204 (13), p.3059-3066

2007

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Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

Molecular and Cellular Biology, 2001-09, Vol.21 (17), p.6006-6016

2001

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Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer

Carcinogenesis (New York), 2008-04, Vol.29 (4), p.747-753

2008

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Take care of your chromosomes lest cancer take care of you

Cancer Cell, 2003, Vol.3 (1), p.4-6

2003

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Keeping telomerase in its place

Nature medicine, 2002-09, Vol.8 (9), p.934-936

2002

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Abstract 1617: Developing new mouse models of metastatic lung cancer

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1617-1617

2020

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Telomere dysfunction induces metabolic and mitochondrial compromise

Telomere Shortening and Mood Disorders: Preliminary Support for a Chronic Stress Model of Accelerated Aging

Connecting Chromosomes, Crisis, and Cancer

Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin

Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development

Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression

Generating Mouse Models Using CRISPR‐Cas9‐Mediated Genome Editing

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

In Situ Visualization of DNA Double-Strand Break Repair in Human Fibroblasts

DNA-Dependent Protein Kinase Catalytic Subunit Is Not Required for Dysfunctional Telomere Fusion and Checkpoint Response in the Telomerase-Deficient Mouse

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response

Genetic mapping in Diversity Outbred mice identifies a Trpa1 variant influencing late-phase formalin response

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

The hMre11/hRad50 Protein Complex and Nijmegen Breakage Syndrome: Linkage of Double-Strand Break Repair to the Cellular DNA Damage Response

hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks

Alu elements mediate MYB gene tandem duplication in human T-ALL

Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

Telomere dysfunction promotes genome instability and metastatic potential in a K-ras p53 mouse model of lung cancer

Take care of your chromosomes lest cancer take care of you

Keeping telomerase in its place

Abstract 1617: Developing new mouse models of metastatic lung cancer

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