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Recent advances of the Povarov reaction in medicinal chemistry

Drug discovery today. Technologies, 2018-11, Vol.29, p.71-79

2018

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Fused 1,5-Naphthyridines: Synthetic Tools and Applications

Molecules (Basel, Switzerland), 2020-07, Vol.25 (15), p.3508

2020

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Synthetic Strategies, Reactivity and Applications of 1,5-Naphthyridines

Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3252

2020

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Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds

Pharmaceuticals (Basel, Switzerland), 2023-04, Vol.16 (5), p.657

2023

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Highly Enantioselective Conjugate Additions of Aldehydes to Vinyl Sulfones

Chemistry : a European journal, 2009-02, Vol.15 (7), p.1562-1565

2009

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In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma

Haematologica (Roma), 2018-11, Vol.103 (11), p.e537-e540

2018

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Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions

Antibiotics (Basel), 2023-01, Vol.12 (1), p.83

2023

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A patent review of topoisomerase I inhibitors (2016-present)

Expert opinion on therapeutic patents, 2021-06, Vol.31 (6), p.473-508

2021

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The Intramolecular Povarov Tool in the Construction of Fused Nitrogen-Containing Heterocycles

Topics in current chemistry (2016), 2023-06, Vol.381 (4), p.20-20, Article 20

2023

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Formation of γ-Oxoacids and 1 H -Pyrrol-2(5 H )-ones from α,β-Unsaturated Ketones and Ethyl Nitroacetate

Journal of organic chemistry, 2010-11, Vol.75 (21), p.7435-7438

2010

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Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4725-4725

2019

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Formation of γ-Oxoacids and 1H-Pyrrol-2(5H)-ones from α,β-Unsaturated Ketones and Ethyl Nitroacetate

Journal of organic chemistry, 2010-11, Vol.75 (21), p.7435-7438

2010

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Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia

Blood, 2018-11, Vol.132 (Supplement 1), p.5383-5383

2018

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Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts

Angewandte Chemie International Edition, 2007-04, Vol.46 (17), p.3043-3046

2007

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Isocyanide Addition to Pyridinium Salts. Efficient Entry into Substituted Nicotinonitrile Derivatives

Organic letters, 2006-12, Vol.8 (25), p.5789-5792

2006

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Multicomponent Access to Functionalized Mesoionic Structures Based on TFAA Activation of Isocyanides: Novel Domino Reactions

European Journal of Organic Chemistry, 2009-02, Vol.2009 (5), p.617-625

2009

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Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study

Biomedical chromatography, 2015-08, Vol.29 (8), p.1249-1258

2015

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Benzimidazolium Salts as Small, Nonpeptidic and BBB-Permeable Human Prolyl Oligopeptidase Inhibitors

ChemMedChem, 2008-10, Vol.3 (10), p.1558-1565

2008

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Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts

Angewandte Chemie, 2007-04, Vol.119 (17), p.3103-3106

2007

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Straightforward α-carbamoylation of NADH-like dihydropyridines and enol ethers

Tetrahedron letters, 2004-10, Vol.45 (42), p.7907-7909

2004

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Introduction of Heteroatom-Based Substituents into 1, 4-Dihydropyridines by Means of a Halogen-Mediated, Oxidative Protocol: Diamination, Sulfonylation, Sulfinylation, Bis-Sulfanylation, and Halo-Phosphonylation Processes

Chemistry : a European journal, 2000-05, Vol.6 (10), p.1763-1772

2000

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Vicinal diamination of 1,4-dihydropyridines

Chemical communications (Cambridge, England), 1998-12 (24), p.2715-2716

1998

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Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts

Angewandte Chemie, 2007-04, Vol.119 (17), p.3103-3106

2007

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“Nonbiomimetic” Oxidations of Dihydropyridines

Journal of organic chemistry, 1998-12, Vol.63 (26), p.10001-10005

1998

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Azole additions upon azinium salts

Tetrahedron, 1997-10, Vol.53 (40), p.13959-13968

1997

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Recent advances of the Povarov reaction in medicinal chemistry

Fused 1,5-Naphthyridines: Synthetic Tools and Applications

Synthetic Strategies, Reactivity and Applications of 1,5-Naphthyridines

Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds

Highly Enantioselective Conjugate Additions of Aldehydes to Vinyl Sulfones

In vitro and in vivo activity of a new small-molecule inhibitor of HDAC6 in mantle cell lymphoma

Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions

A patent review of topoisomerase I inhibitors (2016-present)

The Intramolecular Povarov Tool in the Construction of Fused Nitrogen-Containing Heterocycles

Formation of γ-Oxoacids and 1 H -Pyrrol-2(5 H )-ones from α,β-Unsaturated Ketones and Ethyl Nitroacetate

Abstract 4725: Efficacy of a new small-molecule inhibitor of histone deacetylase 6 (HDAC6) in preclinical models of B-cell lymphoma and acute myeloid leukemia

Formation of γ-Oxoacids and 1H-Pyrrol-2(5H)-ones from α,β-Unsaturated Ketones and Ethyl Nitroacetate

Efficacy of a New Small-Molecule Inhibitor of Histone Deacetylase 6 (HDAC6) in Preclinical Models of B-Cell Lymphoma and Acute Myeloid Leukemia

Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts

Isocyanide Addition to Pyridinium Salts. Efficient Entry into Substituted Nicotinonitrile Derivatives

Multicomponent Access to Functionalized Mesoionic Structures Based on TFAA Activation of Isocyanides: Novel Domino Reactions

Development and validation of a LC-MS assay for the quantification of ikh12 a novel anti-tumor candidate in rat plasma and tissues and its application in a pharmacokinetic study

Benzimidazolium Salts as Small, Nonpeptidic and BBB-Permeable Human Prolyl Oligopeptidase Inhibitors

Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts

Straightforward α-carbamoylation of NADH-like dihydropyridines and enol ethers

Introduction of Heteroatom-Based Substituents into 1, 4-Dihydropyridines by Means of a Halogen-Mediated, Oxidative Protocol: Diamination, Sulfonylation, Sulfinylation, Bis-Sulfanylation, and Halo-Phosphonylation Processes

Vicinal diamination of 1,4-dihydropyridines

Double Insertion of Isocyanides into Dihydropyridines: Direct Access to Substituted Benzimidazolium Salts

“Nonbiomimetic” Oxidations of Dihydropyridines

Azole additions upon azinium salts

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