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Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma

Chest, 2014-06, Vol.145 (6), p.1219-1229

2014

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Discovery and mechanism of ustekinumab: A human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders

mAbs, 2011-11, Vol.3 (6), p.535-545

2011

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Pharmacokinetics and bioavailability of a therapeutic enzyme (idursulfase) in cynomolgus monkeys after intrathecal and intravenous administration

PloS one, 2015-04, Vol.10 (4), p.e0122453-e0122453

2015

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An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis

Journal of Immunology, 2006-10, Vol.177 (7), p.4917-4926

2006

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Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives

Annals of the New York Academy of Sciences, 2011-03, Vol.1222 (1), p.30-39

2011

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Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives - an update

Annals of the New York Academy of Sciences, 2012-08, Vol.1263 (1), p.1-12

2012

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A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis

Current medical research and opinion, 2007-05, Vol.23 (5), p.1081-1092

2007

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A phase I/II study of intrathecal idursulfase-IT in children with severe mucopolysaccharidosis II

Genetics in medicine, 2016-01, Vol.18 (1), p.73-81

2016

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Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations

Journal of allergy and clinical immunology, 2019-01, Vol.143 (1), p.114-125.e4

2019

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Mechanisms of Monoclonal Antibody-Drug Interactions

Annual review of pharmacology and toxicology, 2011-01, Vol.51 (1), p.359-372

2011

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GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood

Thrombosis and haemostasis, 2000-09, Vol.84 (3), p.492-498

2000

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A phase I study assessing the safety, clinical response, and pharmacokinetics of an experimental infliximab formulation for subcutaneous or intramuscular administration in patients with rheumatoid arthritis

Journal of rheumatology, 2006-05, Vol.33 (5), p.847

2006

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Population Pharmacokinetics of Naloxegol in Pediatric Subjects Receiving Opioids

Clinical pharmacology in drug development, 2024-09, Vol.13 (9), p.974-984

2024

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Pharmacokinetics and biodistribution of idursulfase in non-human primates after intrathecal-lumbar administration

Molecular genetics and metabolism, 2015-02, Vol.114 (2), p.S31-S32

2015

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A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

Journal of investigative dermatology, 2004-12, Vol.123 (6), p.1037-1044

2004

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Pharmacokinetics and Safety of Golimumab, a Fully Human Anti-TNF-α Monoclonal Antibody, in Subjects With Rheumatoid Arthritis

Journal of clinical pharmacology, 2007-03, Vol.47 (3), p.383-396

2007

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Readministration of abciximab: Interim report of the ReoPro Readministration Registry

The American heart journal, 1999-07, Vol.138 (1), p.s33-s38

1999

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Molecular, Biologic, and Pharmacokinetic Properties of Monoclonal Antibodies: Impact of These Parameters on Early Clinical Development

Journal of clinical pharmacology, 2007-05, Vol.47 (5), p.553-565

2007

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Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists

Circulation (New York, N.Y.), 2000-03, Vol.101 (9), p.1013-1018

2000

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An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates

Thrombosis and haemostasis, 2002, Vol.87 (6), p.1020-1025

2002

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Long-term biomarker and cognitive follow-up of children with Hunter syndrome receiving intrathecal enzyme replacement therapy

Molecular genetics and metabolism, 2015-02, Vol.114 (2), p.S83-S83

2015

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Abciximab readministration: Results of the reopro readministration registry

Circulation (New York, N.Y.), 2001-08, Vol.104 (8), p.870-875

2001

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Anti-platelet factor 4/heparin antibodies: An independent predictor of 30-day myocardial infarction after acute coronary ischemic syndromes

Circulation (New York, N.Y.), 2003-05, Vol.107 (18), p.2307-2312

2003

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Investigational intrathecal (IT) enzyme replacement therapy for the severe form of Hunter syndrome (mucopolysaccharidosis type II, MPS II)

Molecular genetics and metabolism, 2014-02, Vol.111 (2), p.S79-S79

2014

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Effects of ustekinumab administration on primate/human antigen-recall and humoral immune response functions

Journal of drugs in dermatology, 2010-06, Vol.9 (6), p.677

2010

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Airway Inflammation and Illness Severity in Response to Experimental Rhinovirus Infection in Asthma

Discovery and mechanism of ustekinumab: A human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders

Pharmacokinetics and bioavailability of a therapeutic enzyme (idursulfase) in cynomolgus monkeys after intrathecal and intravenous administration

An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis

Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives

Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives - an update

A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis

A phase I/II study of intrathecal idursulfase-IT in children with severe mucopolysaccharidosis II

Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations

Mechanisms of Monoclonal Antibody-Drug Interactions

GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood

A phase I study assessing the safety, clinical response, and pharmacokinetics of an experimental infliximab formulation for subcutaneous or intramuscular administration in patients with rheumatoid arthritis

Population Pharmacokinetics of Naloxegol in Pediatric Subjects Receiving Opioids

Pharmacokinetics and biodistribution of idursulfase in non-human primates after intrathecal-lumbar administration

A Phase I Study Evaluating the Safety, Pharmacokinetics, and Clinical Response of a Human IL-12 p40 Antibody in Subjects with Plaque Psoriasis

Pharmacokinetics and Safety of Golimumab, a Fully Human Anti-TNF-α Monoclonal Antibody, in Subjects With Rheumatoid Arthritis

Readministration of abciximab: Interim report of the ReoPro Readministration Registry

Molecular, Biologic, and Pharmacokinetic Properties of Monoclonal Antibodies: Impact of These Parameters on Early Clinical Development

Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists

An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates

Long-term biomarker and cognitive follow-up of children with Hunter syndrome receiving intrathecal enzyme replacement therapy

Abciximab readministration: Results of the reopro readministration registry

Anti-platelet factor 4/heparin antibodies: An independent predictor of 30-day myocardial infarction after acute coronary ischemic syndromes

Investigational intrathecal (IT) enzyme replacement therapy for the severe form of Hunter syndrome (mucopolysaccharidosis type II, MPS II)

Effects of ustekinumab administration on primate/human antigen-recall and humoral immune response functions

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