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Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)

Chemical and Pharmaceutical Bulletin, 2021/09/01, Vol.69(9), pp.905-912

2021

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Identification and Synthesis of DDI-6, a Quinolinol Analog Capable of Activating Both Caenorhabditis elegans and Mouse Spermatozoa

Chemical and Pharmaceutical Bulletin, 2021/06/01, Vol.69(6), pp.557-563

2021

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Development of Drug Discovery Platforms Using Artificial Intelligence and Cheminformatics

Chemical and Pharmaceutical Bulletin, 2024/09/01, Vol.72(9), pp.794-799

2024

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Pentafluorosulfanyl-substituted biaryl derivatives as MATE-type transporter inhibitors targeting drug-resistant bacteria

Bioorganic & medicinal chemistry, 2024-02, Vol.99, p.117606-117606, Article 117606

2024

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Synthesis of fluoroalkenes and fluoroenynes via cross-coupling reactions using novel multihalogenated vinyl ethers

Beilstein journal of organic chemistry, 2024-10, Vol.20 (1), p.2691-2703

2024

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Fluorophenylalkyl-substituted cyanoguanidine derivatives as bacteria-selective MATE transporter inhibitors for the treatment of antibiotic-resistant infections

Bioorganic & medicinal chemistry, 2022-11, Vol.74, p.117042-117042, Article 117042

2022

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Stereoselective Synthesis of Multisubstituted α-fluoro-β-lactams

Current organic chemistry, 2020-01, Vol.24 (18), p.2169-2180

2020

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Ferulic acid alleviates abnormal behaviors in isolation-reared mice via 5-HT1A receptor partial agonist activity

Psychopharmacology, 2021-08, Vol.238 (8), p.2147-2154

2021

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Synthesis of aryl 2-bromo-2-chloro-1,1-difluoroethyl ethers through the base-mediated reaction between phenols and halothane

Beilstein journal of organic chemistry, 2021-01, Vol.17 (1), p.89-96

2021

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Synthesis of new fluorescent molecules having an aggregation-induced emission property derived from 4-fluoroisoxazoles

Beilstein journal of organic chemistry, 2020-06, Vol.16 (1), p.1411-1417

2020

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In vitro demonstration of antedrug mechanism of a pharmacokinetic booster to improve CYP3A4 substrates by CYP3A4-mediated metabolism inhibition

Drug metabolism and pharmacokinetics, 2024-06, Vol.56, p.101005, Article 101005

2024

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Effect of Structural Descriptors on the Design of Cyclin Dependent Kinase Inhibitors Using Similarity‐based Molecular Evolution

Molecular informatics, 2020-05, Vol.39 (5), p.e1900126-n/a

2020

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LCP: Simple Representation of Docking Poses for Machine Learning: A Case Study on Xanthine Oxidase Inhibitors

Molecular informatics, 2022-05, Vol.41 (5), p.e2100245-n/a

2022

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Rhodium-catalyzed homo-coupling reaction of aryl Grignard reagents and its application for the synthesis of an integrin inhibitor

Beilstein journal of organic chemistry, 2024-06, Vol.20 (1), p.1341-1347

2024

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Proteinase K is an activator for the male‐dependent spermiogenesis pathway in Caenorhabditis elegans: Its application to pharmacological dissection of spermiogenesis

Genes to cells : devoted to molecular & cellular mechanisms, 2019-03, Vol.24 (3), p.244-258

2019

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Trifluoromethylation of Organic Compounds and Related Reactions

Synthesis (Stuttgart), 2010-06, Vol.2010 (11), p.1865-1882

2010

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Decarboxylative Aldol Reaction of α,α-Difluoro-β-keto Esters: Easy Access to Difluoroenolate

ACS omega, 2024-06, Vol.9 (24), p.26275-26284

2024

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Ligand-Promoted Asymmetric Imino-Reformatsky Reaction of Ethyl Dibromofluoroacetate

Organic letters, 2014-04, Vol.16 (8), p.2080-2083

2014

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Synthesis of Small Fluorescent Molecules and Evaluation of Photophysical Properties

Journal of organic chemistry, 2020-01, Vol.85 (2), p.1253-1258

2020

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Synthesis of 2,2-difluoro-2-arylethylamines as fluorinated analogs of octopamine and noradrenaline

Heterocyclic Communications, 2022-03, Vol.28 (1), p.26-34

2022

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Synthesis of 2-aryl-3-trifluoromethylquinolines using (E)-trimethyl(3,3,3-trifluoroprop-1-enyl)silane

Journal of organic chemistry, 2013-06, Vol.78 (12), p.6196-6201

2013

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Development of a fluorogenic small substrate for dipeptidyl peptidase-4

Beilstein journal of organic chemistry, 2017-12, Vol.13 (1), p.2690-2697

2017

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Rh-Catalyzed reductive Mannich-type reaction and its application towards the synthesis of (±)-ezetimibe

Beilstein journal of organic chemistry, 2016-07, Vol.12 (1), p.1608-1615

2016

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Diastereoselective synthesis of 2-fluoroaziridine-2-carboxylates by Reformatsky-type aza-Darzens reaction

Tetrahedron letters, 2010-08, Vol.51 (32), p.4246-4249

2010

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Asymmetric Reductive Aldol-Type Reaction with Carbonyl Compounds Using Dialkyl Tartrate as a Chiral Ligand

Chemical and Pharmaceutical Bulletin, 2014/10/01, Vol.62(10), pp.956-961

2014

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Importance of the Azole Moiety of Cimetidine Derivatives for the Inhibition of Human Multidrug and Toxin Extrusion Transporter 1 (hMATE1)

Identification and Synthesis of DDI-6, a Quinolinol Analog Capable of Activating Both Caenorhabditis elegans and Mouse Spermatozoa

Development of Drug Discovery Platforms Using Artificial Intelligence and Cheminformatics

Pentafluorosulfanyl-substituted biaryl derivatives as MATE-type transporter inhibitors targeting drug-resistant bacteria

Synthesis of fluoroalkenes and fluoroenynes via cross-coupling reactions using novel multihalogenated vinyl ethers

Fluorophenylalkyl-substituted cyanoguanidine derivatives as bacteria-selective MATE transporter inhibitors for the treatment of antibiotic-resistant infections

Stereoselective Synthesis of Multisubstituted α-fluoro-β-lactams

Ferulic acid alleviates abnormal behaviors in isolation-reared mice via 5-HT1A receptor partial agonist activity

Synthesis of aryl 2-bromo-2-chloro-1,1-difluoroethyl ethers through the base-mediated reaction between phenols and halothane

Synthesis of new fluorescent molecules having an aggregation-induced emission property derived from 4-fluoroisoxazoles

In vitro demonstration of antedrug mechanism of a pharmacokinetic booster to improve CYP3A4 substrates by CYP3A4-mediated metabolism inhibition

Effect of Structural Descriptors on the Design of Cyclin Dependent Kinase Inhibitors Using Similarity‐based Molecular Evolution

LCP: Simple Representation of Docking Poses for Machine Learning: A Case Study on Xanthine Oxidase Inhibitors

Rhodium-catalyzed homo-coupling reaction of aryl Grignard reagents and its application for the synthesis of an integrin inhibitor

Proteinase K is an activator for the male‐dependent spermiogenesis pathway in Caenorhabditis elegans: Its application to pharmacological dissection of spermiogenesis

Trifluoromethylation of Organic Compounds and Related Reactions

Decarboxylative Aldol Reaction of α,α-Difluoro-β-keto Esters: Easy Access to Difluoroenolate

Ligand-Promoted Asymmetric Imino-Reformatsky Reaction of Ethyl Dibromofluoroacetate

Synthesis of Small Fluorescent Molecules and Evaluation of Photophysical Properties

Synthesis of 2,2-difluoro-2-arylethylamines as fluorinated analogs of octopamine and noradrenaline

Synthesis of 2-aryl-3-trifluoromethylquinolines using (E)-trimethyl(3,3,3-trifluoroprop-1-enyl)silane

Development of a fluorogenic small substrate for dipeptidyl peptidase-4

Rh-Catalyzed reductive Mannich-type reaction and its application towards the synthesis of (±)-ezetimibe

Diastereoselective synthesis of 2-fluoroaziridine-2-carboxylates by Reformatsky-type aza-Darzens reaction

Asymmetric Reductive Aldol-Type Reaction with Carbonyl Compounds Using Dialkyl Tartrate as a Chiral Ligand

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