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Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis

Nature biotechnology, 2020-11, Vol.38 (11), p.1288-1297

2020

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Mimicry of High-Density Lipoprotein: Functional Peptide–Lipid Nanoparticles Based on Multivalent Peptide Constructs

Journal of the American Chemical Society, 2013-09, Vol.135 (36), p.13414-13424

2013

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Thrombogenic Collagen-Mimetic Peptides: Self-Assembly of Triple Helix-Based Fibrils Driven by Hydrophobic Interactions

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (25), p.8513-8518

2008

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In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I[S]

Journal of lipid research, 2014-10, Vol.55 (10), p.2053-2063

2014

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Molecular Pharmacodynamics, Clinical Therapeutics, and Pharmacokinetics of Topiramate

CNS neuroscience & therapeutics, 2008-06, Vol.14 (2), p.120-142

2008

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Editorial on First-Time Disclosures of Clinical Candidates

Journal of medicinal chemistry, 2018-07, Vol.61 (13), p.5449-5449

Maryanoff, Bruce E

2018

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Nonpeptide Urotensin-II Receptor Antagonists: A New Ligand Class Based on Piperazino-Phthalimide and Piperazino-Isoindolinone Subunits

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7432-7445

2009

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Synthesis of Macrocycles via Cobalt-Mediated [2 + 2 + 2] Cycloadditions

Journal of the American Chemical Society, 2005-03, Vol.127 (10), p.3473-3485

2005

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Self-Assembling Cyclic d,l‑α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents

ACS central science, 2017-06, Vol.3 (6), p.639-646

2017

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Phenotypic Assessment and the Discovery of Topiramate

ACS medicinal chemistry letters, 2016-07, Vol.7 (7), p.662-665

Maryanoff, Bruce E

2016

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Cyclizations of N-Acyliminium Ions

Chemical reviews, 2004-03, Vol.104 (3), p.1431-1628

2004

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Molecules That Mimic Apolipoprotein A‑I: Potential Agents for Treating Atherosclerosis

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2169-2196

2014

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Blockade of the thrombin receptor protease-activated receptor-1 with a small-molecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates

The Journal of pharmacology and experimental therapeutics, 2003-02, Vol.304 (2), p.855

2003

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First-Time Disclosures of Clinical Candidates

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.575-575

Maryanoff, Bruce E

2018

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Presenting a Special Issue on “Medicinal Chemistry: From Targets to Therapies”

ACS medicinal chemistry letters, 2020-10, Vol.11 (10), p.1780-1782

2020

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Potency variation of small-molecule chymase inhibitors across species

Biochemical pharmacology, 2010-10, Vol.80 (7), p.1033-1041

2010

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Pharmacokinetic and Metabolic Investigation of Topiramate Disposition in Healthy Subjects in the Absence and in the Presence of Enzyme Induction by Carbamazepine

Epilepsia (Copenhagen), 2005-03, Vol.46 (3), p.378-384

2005

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Facile Solid-Phase Construction of Indole Derivatives Based on a Traceless, Activating Sulfonyl Linker

Organic letters, 2000-01, Vol.2 (1), p.89-92

2000

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Cobalt-mediated cyclotrimerisation of bis-alkynes and cyanamides

Chemical communications (Cambridge, England), 2004-11 (21), p.2394-2395

2004

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Medicinal Chemistry: From Targets to Therapies

ACS medicinal chemistry letters, 2019-07, Vol.10 (7), p.1014-1014

2019

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Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase

Journal of medicinal chemistry, 2007-04, Vol.50 (8), p.1727-1730

2007

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Deuterated Drug Molecules: Focus on FDA-Approved Deutetrabenazine: Published as part of the Biochemistry series “Biochemistry to Bedside”

Biochemistry (Easton), 2018-02, Vol.57 (5), p.472-473

2018

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Pharmaceutical “Gold” from Neurostabilizing Agents: Topiramate and Successor Molecules

Journal of medicinal chemistry, 2009-06, Vol.52 (11), p.3431-3440

Maryanoff, Bruce E

2009

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The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

Chemical reviews, 1989-06, Vol.89 (4), p.863-927

1989

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Design, Synthesis, and Biological Characterization of a Peptide-Mimetic Antagonist for a Tethered-Ligand Receptor

Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12257-12262

1999

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Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis

Mimicry of High-Density Lipoprotein: Functional Peptide–Lipid Nanoparticles Based on Multivalent Peptide Constructs

Thrombogenic Collagen-Mimetic Peptides: Self-Assembly of Triple Helix-Based Fibrils Driven by Hydrophobic Interactions

In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein A-I[S]

Molecular Pharmacodynamics, Clinical Therapeutics, and Pharmacokinetics of Topiramate

Editorial on First-Time Disclosures of Clinical Candidates

Nonpeptide Urotensin-II Receptor Antagonists: A New Ligand Class Based on Piperazino-Phthalimide and Piperazino-Isoindolinone Subunits

Synthesis of Macrocycles via Cobalt-Mediated [2 + 2 + 2] Cycloadditions

Self-Assembling Cyclic d,l‑α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents

Phenotypic Assessment and the Discovery of Topiramate

Cyclizations of N-Acyliminium Ions

Molecules That Mimic Apolipoprotein A‑I: Potential Agents for Treating Atherosclerosis

Blockade of the thrombin receptor protease-activated receptor-1 with a small-molecule antagonist prevents thrombus formation and vascular occlusion in nonhuman primates

First-Time Disclosures of Clinical Candidates

Presenting a Special Issue on “Medicinal Chemistry: From Targets to Therapies”

Potency variation of small-molecule chymase inhibitors across species

Pharmacokinetic and Metabolic Investigation of Topiramate Disposition in Healthy Subjects in the Absence and in the Presence of Enzyme Induction by Carbamazepine

Facile Solid-Phase Construction of Indole Derivatives Based on a Traceless, Activating Sulfonyl Linker

Cobalt-mediated cyclotrimerisation of bis-alkynes and cyanamides

Medicinal Chemistry: From Targets to Therapies

Discovery of Potent, Selective, Orally Active, Nonpeptide Inhibitors of Human Mast Cell Chymase

Deuterated Drug Molecules: Focus on FDA-Approved Deutetrabenazine: Published as part of the Biochemistry series “Biochemistry to Bedside”

Pharmaceutical “Gold” from Neurostabilizing Agents: Topiramate and Successor Molecules

The Wittig olefination reaction and modifications involving phosphoryl-stabilized carbanions. Stereochemistry, mechanism, and selected synthetic aspects

Design, Synthesis, and Biological Characterization of a Peptide-Mimetic Antagonist for a Tethered-Ligand Receptor

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