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Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors

Nature communications, 2014-05, Vol.5 (1), p.3901, Article 3901

2014

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MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance

Cell death & disease, 2021-11, Vol.12 (12), p.1111-1111, Article 1111

2021

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Kinase inhibitors for precision therapy of triple-negative breast cancer: Progress, challenges, and new perspectives on targeting this heterogeneous disease

Cancer letters, 2022-10, Vol.547, p.215775-215775, Article 215775

2022

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Drivers of cancer metastasis – Arise early and remain present

Biochimica et biophysica acta. Reviews on cancer, 2024-03, Vol.1879 (2), p.189060-189060, Article 189060

2024

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Protocols for Co-Culture Phenotypic Assays with Breast Cancer Cells and THP-1-Derived Macrophages

Journal of mammary gland biology and neoplasia, 2024-12, Vol.29 (1), p.4-4, Article 4

2024

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Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (30), p.12426-12431

2013

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Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

EMBO molecular medicine, 2016-02, Vol.8 (2), p.105-116

2016

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lncRNA DIRC3 regulates invasiveness and insulin-like growth factor signaling in thyroid cancer cells

Endocrine-related cancer, 2023-08, Vol.30 (8), p.1

2023

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Inhibition of the ʟ-glutamine transporter ASCT2 sensitizes plasma cell myeloma cells to proteasome inhibitors

Cancer letters, 2021-06, Vol.507, p.13-25

2021

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Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC

Journal of medicinal chemistry, 2024-08, Vol.67 (17), p.15012-15028

2024

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PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer

Cell chemical biology, 2024-02, Vol.31 (2), p.326-337.e11

2024

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Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells

Oncogene, 2019-04, Vol.38 (15), p.2860-2875

2019

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Corrigendum to “Inhibition of the ʟ-glutamine transporter ASCT2 sensitizes plasma cell myeloma cells to proteasome inhibitors” [Canc. Lett. 507 (2021) 13–25]

Cancer letters, 2022-02, Vol.526, p.363-363

2022

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Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell‐Defective Apoptosis and Hyperproliferation

Arthritis & rheumatology (Hoboken, N.J.), 2013-08, Vol.65 (8), p.2161-2171

2013

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Protein Kinase C[delta] Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell-Defective Apoptosis and Hyperproliferation

Arthritis & rheumatology (Hoboken, N.J.), 2013-08, Vol.65 (8), p.2161

2013

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Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study

Scientific reports, 2020-05, Vol.10 (1), p.7950, Article 7950

2020

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Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (3), p.724-735

2016

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Abstract 4408: Mutant ABL1 is a genetic dependency in non-small cell lung cancer amenable to pharmacological intervention

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4408-4408

2016

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Abstract 151: Mixed-lineage kinase 4 is involved in the activation of the ATM-NEMO signaling axis in response to DNA damage and confers chemoresistance in triple-negative breast cancer

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.151-151

2022

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Somatically mutated ABL 1 is an actionable and essential NSCLC survival gene

EMBO molecular medicine, 2016-02, Vol.8 (2), p.105-116

2016

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Motor imagery training of goal-directed reaching in relation to imagery of reaching and grasping in healthy people

Scientific reports, 2022-11, Vol.12 (1), p.18610-18610, Article 18610

2022

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High-intensity interval training modulates inflammatory response in Parkinson’s disease

Aging clinical and experimental research, 2022-09, Vol.34 (9), p.2165-2176

2022

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Muscle stiffness at different force levels measured with two myotonometric devices

Physiological measurement, 2012-01, Vol.33 (1), p.65-78

2012

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Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors

MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance

Kinase inhibitors for precision therapy of triple-negative breast cancer: Progress, challenges, and new perspectives on targeting this heterogeneous disease

Drivers of cancer metastasis – Arise early and remain present

Protocols for Co-Culture Phenotypic Assays with Breast Cancer Cells and THP-1-Derived Macrophages

Targeted genetic dependency screen facilitates identification of actionable mutations in FGFR4, MAP3K9, and PAK5 in lung cancer

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

lncRNA DIRC3 regulates invasiveness and insulin-like growth factor signaling in thyroid cancer cells

Inhibition of the ʟ-glutamine transporter ASCT2 sensitizes plasma cell myeloma cells to proteasome inhibitors

Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC

PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer

Upregulation of MLK4 promotes migratory and invasive potential of breast cancer cells

Corrigendum to “Inhibition of the ʟ-glutamine transporter ASCT2 sensitizes plasma cell myeloma cells to proteasome inhibitors” [Canc. Lett. 507 (2021) 13–25]

Protein Kinase Cδ Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell‐Defective Apoptosis and Hyperproliferation

Protein Kinase C[delta] Deficiency Causes Mendelian Systemic Lupus Erythematosus With B Cell-Defective Apoptosis and Hyperproliferation

Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study

Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis

Abstract 4408: Mutant ABL1 is a genetic dependency in non-small cell lung cancer amenable to pharmacological intervention

Paradox-Breaking RAF Inhibitors that Also Target SRC Are Effective in Drug-Resistant BRAF Mutant Melanoma

Abstract 151: Mixed-lineage kinase 4 is involved in the activation of the ATM-NEMO signaling axis in response to DNA damage and confers chemoresistance in triple-negative breast cancer

Somatically mutated ABL 1 is an actionable and essential NSCLC survival gene

Motor imagery training of goal-directed reaching in relation to imagery of reaching and grasping in healthy people

High-intensity interval training modulates inflammatory response in Parkinson’s disease

Muscle stiffness at different force levels measured with two myotonometric devices

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