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An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity

Neurotoxicology (Park Forest South), 2019-07, Vol.73, p.17-30

2019

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An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept

Regulatory toxicology and pharmacology, 2015-04, Vol.71 (3), p.398-408

2015

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Mode of action and human relevance of pronamide-induced rat thyroid tumors

Regulatory toxicology and pharmacology, 2015-04, Vol.71 (3), p.541-551

2015

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Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing – An integrated approach without additional animal use

Regulatory toxicology and pharmacology, 2012-07, Vol.63 (2), p.321-332

2012

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The Effect of Plasma Lipids on the Pharmacokinetics of Chlorpyrifos and the Impact on Interpretation of Blood Biomonitoring Data

Toxicological sciences, 2009-04, Vol.108 (2), p.258-272

2009

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Distinguishing between endocrine disruption and non-specific effects on endocrine systems

Regulatory toxicology and pharmacology, 2018-11, Vol.99, p.142-158

2018

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Animal metrics: Tracking contributions of new approach methods to reduced animal use

ALTEX, alternatives to animal experimentation, 2022-01, Vol.39 (1), p.95-112

2022

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Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods

Pharmacological reviews, 2024-03, Vol.76 (2), p.251-266

2024

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Key Learnings from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 In Vitro Assays

Birth defects research. Part B. Developmental and reproductive toxicology, 2014-02, Vol.101 (1), p.23-42

2014

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An in vitro developmental neurotoxicity screening assay for retinoic acid-induced neuronal differentiation using the human NT2/D1 cell line

Neurotoxicology (Park Forest South), 2019-07, Vol.73, p.258-264

2019

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Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny-part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?

Critical reviews in toxicology, 2022-08, Vol.52 (7), p.546-617

2022

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A reproductive and developmental toxicity screening study of 1,3-butadiene in Sprague-Dawley rats

Regulatory toxicology and pharmacology, 2021-12, Vol.127, p.105066-105066, Article 105066

2021

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Practical considerations for developmental thyroid toxicity assessments: What's working, what's not, and how can we do better?

Regulatory toxicology and pharmacology, 2019-08, Vol.106, p.111-136

2019

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A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study

Critical reviews in toxicology, 2016-10, Vol.46 (9), p.785-833

2016

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Initial Insights Regarding the Role of p53 in Maintaining Sperm DNA Integrity Following Treatment of Mice with Ethylnitrosourea or Cyclophosphamide

Toxicologic pathology, 2010-02, Vol.38 (2), p.244-257

2010

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Comparative sensitivity of rat cerebellar neurons to dysregulation of divalent cation homeostasis and cytotoxicity caused by methylmercury

Toxicology and applied pharmacology, 2005-11, Vol.208 (3), p.222-232

2005

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Developmental Neurotoxicity Study of Dietary Bisphenol A in Sprague-Dawley Rats

Toxicological sciences, 2010-05, Vol.115 (1), p.167-182

2010

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Key Learnings from the Endocrine Disruptor Screening Program (EDSP) Tier 1 Rodent Uterotrophic and Hershberger Assays

Birth defects research. Part B. Developmental and reproductive toxicology, 2014-02, Vol.101 (1), p.63-79

2014

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Chlorpyrifos: Weight of evidence evaluation of potential interaction with the estrogen, androgen, or thyroid pathways

Regulatory toxicology and pharmacology, 2013-08, Vol.66 (3), p.249-263

2013

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A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity

Toxicology and applied pharmacology, 2005, Vol.202 (1), p.108-120

2005

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Developing scientific confidence in HTS-derived prediction models: Lessons learned from an endocrine case study

Regulatory toxicology and pharmacology, 2014-08, Vol.69 (3), p.443-450

2014

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Key Lessons from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 Male and Female Pubertal Assays

Birth defects research. Part B. Developmental and reproductive toxicology, 2014-02, Vol.101 (1), p.43-62

2014

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Evaluation of Tier I Screening Approaches for Detecting Endocrine-Active Compounds (EACs)

Critical reviews in toxicology, 2002-01, Vol.32 (6), p.521-549

2002

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Pronamide: Human relevance of liver-mediated rat leydig cell tumors

Regulatory toxicology and pharmacology, 2015-07, Vol.72 (2), p.394-404

2015

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An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity

An exposure:activity profiling method for interpreting high-throughput screening data for estrogenic activity—Proof of concept

Mode of action and human relevance of pronamide-induced rat thyroid tumors

Assessment of diurnal systemic dose of agrochemicals in regulatory toxicity testing – An integrated approach without additional animal use

The Effect of Plasma Lipids on the Pharmacokinetics of Chlorpyrifos and the Impact on Interpretation of Blood Biomonitoring Data

Distinguishing between endocrine disruption and non-specific effects on endocrine systems

Animal metrics: Tracking contributions of new approach methods to reduced animal use

Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods

Key Learnings from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 In Vitro Assays

An in vitro developmental neurotoxicity screening assay for retinoic acid-induced neuronal differentiation using the human NT2/D1 cell line

Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny-part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?

A reproductive and developmental toxicity screening study of 1,3-butadiene in Sprague-Dawley rats

Adversity Considerations for Thyroid Follicular Cell Hypertrophy and Hyperplasia in Nonclinical Toxicity Studies: Results From the 6th ESTP International Expert Workshop

Practical considerations for developmental thyroid toxicity assessments: What's working, what's not, and how can we do better?

A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study

Initial Insights Regarding the Role of p53 in Maintaining Sperm DNA Integrity Following Treatment of Mice with Ethylnitrosourea or Cyclophosphamide

Comparative sensitivity of rat cerebellar neurons to dysregulation of divalent cation homeostasis and cytotoxicity caused by methylmercury

Developmental Neurotoxicity Study of Dietary Bisphenol A in Sprague-Dawley Rats

Key Learnings from the Endocrine Disruptor Screening Program (EDSP) Tier 1 Rodent Uterotrophic and Hershberger Assays

Chlorpyrifos: Weight of evidence evaluation of potential interaction with the estrogen, androgen, or thyroid pathways

A comparison of in vitro and in vivo EDSTAC test battery results for detecting antiandrogenic activity

Developing scientific confidence in HTS-derived prediction models: Lessons learned from an endocrine case study

Key Lessons from Performance of the U.S. EPA Endocrine Disruptor Screening Program (EDSP) Tier 1 Male and Female Pubertal Assays

Evaluation of Tier I Screening Approaches for Detecting Endocrine-Active Compounds (EACs)

Pronamide: Human relevance of liver-mediated rat leydig cell tumors

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