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ACT‐1004‐1239, a first‐in‐class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases

The FASEB journal, 2021-03, Vol.35 (3), p.e21431-n/a

2021

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Resolution of a chronic viral infection after interleukin-10 receptor blockade

The Journal of experimental medicine, 2006-10, Vol.203 (11), p.2461-2472

2006

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Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

The Journal of experimental medicine, 2009-06, Vol.206 (6), p.1245-1252

2009

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Cenerimod, a selective S1P1 receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren’s syndrome

Arthritis research & therapy, 2021-11, Vol.23 (1), p.1-289, Article 289

2021

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CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis

Frontiers in pharmacology, 2021-11, Vol.12, p.748740-748740

2021

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A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy

PloS one, 2010-12, Vol.5 (12), p.e15732-e15732

2010

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Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes

Clinical and experimental immunology, 2023-12, Vol.214 (2), p.131-143

2023

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ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating Effects

Neurochemical research, 2024-08, Vol.49 (8), p.2087-2104

2024

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The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8 + Thymocyte Selection

The Journal of immunology (1950), 2017-04, Vol.198 (7), p.2649-2660

2017

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Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies

Journal of medicinal chemistry, 2023-03, Vol.66 (6), p.4179-4196

2023

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Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis

Innovations in clinical neuroscience, 2019-03, Vol.16 (3-4), p.22-30

2019

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Transection of Major Histocompatibility Complex Class I-Induced Neurites by Cytotoxic T Lymphocytes

The American journal of pathology, 2001-09, Vol.159 (3), p.809-815

2001

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Real-time imaging of the pancreas during development of diabetes

Immunological reviews, 2008-02, Vol.221 (1), p.200-213

2008

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Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus

Rheumatic & musculoskeletal diseases open, 2020-09, Vol.6 (2), p.e001261

2020

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Novel strategies to eliminate persistent viral infections

Trends in immunology, 2008-03, Vol.29 (3), p.116-124

2008

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MHC class I‐restricted killing of neurons by virus‐specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway

European journal of immunology, 2000-12, Vol.30 (12), p.3623-3633

2000

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LO-016 The multifaceted immunomodulatory properties of cenerimod, a selective S1P1 receptor modulator, target three key aspects of SLE pathogenesis

Lupus science & medicine, 2023-07, Vol.10 (Suppl 1), p.A13-A14

2023

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CpG-Containing Oligonucleotides Are Efficient Adjuvants for Induction of Protective Antiviral Immune Responses with T-Cell Peptide Vaccines

Journal of Virology, 1999-05, Vol.73 (5), p.4120-4126

1999

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CD4 + T-cell-epitope escape mutant virus selected in vivo

Nature medicine, 2001-07, Vol.7 (7), p.795-800

2001

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Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis

Journal of autoimmunity, 2010-12, Vol.35 (4), p.404-413

2010

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Minimal Impact of a De Novo–Expressed β-Cell Autoantigen on Spontaneous Diabetes Development in NOD Mice

Diabetes (New York, N.Y.), 2007-04, Vol.56 (4), p.1059-1068

2007

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Control of graft‐versus‐host disease by regulatory T cells: Which level of antigen specificity?

European Journal of Immunology, 2006-09, Vol.36 (9), p.2299-2303

2006

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Functional CD8⁺ but Not CD4⁺ T Cell Responses Develop Independent of Thymic Epithelial MHC

Proceedings of the National Academy of Sciences - PNAS, 2006-09, Vol.103 (39), p.14435-14440

2006

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Efficient T Cell Repertoire Selection in Tetraparental Chimeric Mice Independent of Thymic Epithelial MHC

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1861-1866

2003

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Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus

Rheumatic & musculoskeletal diseases open, 2020-09, Vol.6 (2), p.e001261

2020

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ACT‐1004‐1239, a first‐in‐class CXCR7 antagonist with both immunomodulatory and promyelinating effects for the treatment of inflammatory demyelinating diseases

Resolution of a chronic viral infection after interleukin-10 receptor blockade

Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity

Cenerimod, a selective S1P1 receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren’s syndrome

CXCR7 Antagonism Reduces Acute Lung Injury Pathogenesis

A novel technique for the in vivo imaging of autoimmune diabetes development in the pancreas by two-photon microscopy

Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes

ACKR3 Antagonism Enhances the Repair of Demyelinated Lesions Through Both Immunomodulatory and Remyelinating Effects

The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8 + Thymocyte Selection

Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies

Therapeutic Potential of Ponesimod Alone and in Combination with Dimethyl Fumarate in Experimental Models of Multiple Sclerosis

Transection of Major Histocompatibility Complex Class I-Induced Neurites by Cytotoxic T Lymphocytes

Real-time imaging of the pancreas during development of diabetes

Preclinical to clinical translation of cenerimod, a novel S1P 1 receptor modulator, in systemic lupus erythematosus

Novel strategies to eliminate persistent viral infections

MHC class I‐restricted killing of neurons by virus‐specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway

LO-016 The multifaceted immunomodulatory properties of cenerimod, a selective S1P1 receptor modulator, target three key aspects of SLE pathogenesis

CpG-Containing Oligonucleotides Are Efficient Adjuvants for Induction of Protective Antiviral Immune Responses with T-Cell Peptide Vaccines

CD4 + T-cell-epitope escape mutant virus selected in vivo

Expression level of a pancreatic neo-antigen in beta cells determines degree of diabetes pathogenesis

Minimal Impact of a De Novo–Expressed β-Cell Autoantigen on Spontaneous Diabetes Development in NOD Mice

Control of graft‐versus‐host disease by regulatory T cells: Which level of antigen specificity?

Functional CD8⁺ but Not CD4⁺ T Cell Responses Develop Independent of Thymic Epithelial MHC

Efficient T Cell Repertoire Selection in Tetraparental Chimeric Mice Independent of Thymic Epithelial MHC

Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus

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