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Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules

Neuropharmacology, 2013-12, Vol.75, p.567-582

2013

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Stretch-Induced Activation of Pannexin 1 Channels Can Be Prevented by PKA-Dependent Phosphorylation

International journal of molecular sciences, 2020-12, Vol.21 (23), p.9180

2020

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Differential Regulation of Hemichannels and Gap Junction Channels by RhoA GTPase and Actin Cytoskeleton: A Comparative Analysis of Cx43 and Cx26

International journal of molecular sciences, 2024-07, Vol.25 (13), p.7246

2024

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Gap-junction channels dysfunction in deafness and hearing loss

Antioxidants & redox signaling, 2009-02, Vol.11 (2), p.309-322

2009

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β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation

Neurobiology of disease, 2019-10, Vol.130, p.104497-104497, Article 104497

2019

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An Update on Connexin Gap Junction and Hemichannels in Diabetic Retinopathy

International journal of molecular sciences, 2021-03, Vol.22 (6), p.3194

2021

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From Hyperactive Connexin26 Hemichannels to Impairments in Epidermal Calcium Gradient and Permeability Barrier in the Keratitis-Ichthyosis-Deafness Syndrome

Journal of investigative dermatology, 2016-03, Vol.136 (3), p.574-583

2016

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A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII

Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (32), p.1-10

2021

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Supporting Cells and Their Potential Roles in Cisplatin-Induced Ototoxicity

Frontiers in neuroscience, 2022-04, Vol.16, p.867034-867034

2022

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Unnexin is a protein subunit of a large-pore channel expressed by unicellular organisms

Proceedings of the National Academy of Sciences - PNAS, 2023-08, Vol.120 (31), p.e2307898120-e2307898120

2023

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Keratitis-Ichthyosis-Deafness Syndrome-Associated Cx26 Mutants Produce Nonfunctional Gap Junctions but Hyperactive Hemichannels When Co-Expressed With Wild Type Cx43

Journal of investigative dermatology, 2015-05, Vol.135 (5), p.1338-1347

2015

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Connexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket

Biological research, 2024-05, Vol.57 (1), p.31-31, Article 31

2024

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Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells

PloS one, 2013-08, Vol.8 (8), p.e70638-e70638

2013

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Pannexin-1 Channels Are Essential for Mast Cell Degranulation Triggered During Type I Hypersensitivity Reactions

Frontiers in immunology, 2019-11, Vol.10, p.2703-2703

2019

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Gain-of-Function Dynamin-2 Mutations Linked to Centronuclear Myopathy Impair Ca2+-Induced Exocytosis in Human Myoblasts

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10363

2022

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Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1069

2021

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Autocrine activation of P2X7 receptors mediates catecholamine secretion in chromaffin cells

British journal of pharmacology, 2024-08, Vol.181 (16), p.2905-2922

2024

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Redox-mediated regulation of connexin proteins; focus on nitric oxide

Biochimica et biophysica acta. Biomembranes, 2018-01, Vol.1860 (1), p.91-95

2018

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MATE1 expression in the cochlea and its potential involvement in cisplatin cellular uptake and ototoxicity

Acta oto-laryngologica, 2023-03, Vol.143 (3), p.242-249

2023

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Diseases associated with leaky hemichannels

Frontiers in cellular neuroscience, 2015-07, Vol.9, p.267-267

2015

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Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity

Biomolecules (Basel, Switzerland), 2023-05, Vol.13 (6), p.887

2023

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Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3)

Frontiers in physiology, 2020-01, Vol.10, p.1574-1574

2020

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Correlative light and X-ray tomography jointly unveil the critical role of connexin43 channels on inflammation-induced cellular ultrastructural alterations

Heliyon, 2024-04, Vol.10 (7), p.e27888-e27888, Article e27888

2024

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Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice

Frontiers in molecular neuroscience, 2018-04, Vol.11, p.114-114

2018

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The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels

The Journal of general physiology, 2018-05, Vol.150 (5), p.697-711

2018

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Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules

Stretch-Induced Activation of Pannexin 1 Channels Can Be Prevented by PKA-Dependent Phosphorylation

Differential Regulation of Hemichannels and Gap Junction Channels by RhoA GTPase and Actin Cytoskeleton: A Comparative Analysis of Cx43 and Cx26

Gap-junction channels dysfunction in deafness and hearing loss

β-catenin aggregation in models of ALS motor neurons: GSK3β inhibition effect and neuronal differentiation

An Update on Connexin Gap Junction and Hemichannels in Diabetic Retinopathy

From Hyperactive Connexin26 Hemichannels to Impairments in Epidermal Calcium Gradient and Permeability Barrier in the Keratitis-Ichthyosis-Deafness Syndrome

A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII

Supporting Cells and Their Potential Roles in Cisplatin-Induced Ototoxicity

Unnexin is a protein subunit of a large-pore channel expressed by unicellular organisms

Keratitis-Ichthyosis-Deafness Syndrome-Associated Cx26 Mutants Produce Nonfunctional Gap Junctions but Hyperactive Hemichannels When Co-Expressed With Wild Type Cx43

Connexin channels and hemichannels are modulated differently by charge reversal at residues forming the intracellular pocket

Dynamin-2 regulates fusion pore expansion and quantal release through a mechanism that involves actin dynamics in neuroendocrine chromaffin cells

Pannexin-1 Channels Are Essential for Mast Cell Degranulation Triggered During Type I Hypersensitivity Reactions

Gain-of-Function Dynamin-2 Mutations Linked to Centronuclear Myopathy Impair Ca2+-Induced Exocytosis in Human Myoblasts

Restraint of Human Skin Fibroblast Motility, Migration, and Cell Surface Actin Dynamics, by Pannexin 1 and P2X7 Receptor Signaling

Autocrine activation of P2X7 receptors mediates catecholamine secretion in chromaffin cells

Redox-mediated regulation of connexin proteins; focus on nitric oxide

MATE1 expression in the cochlea and its potential involvement in cisplatin cellular uptake and ototoxicity

Diseases associated with leaky hemichannels

Pannexin-1 Modulates Inhibitory Transmission and Hippocampal Synaptic Plasticity

Contribution of Connexin Hemichannels to the Decreases in Cell Viability Induced by Linoleic Acid in the Human Lens Epithelial Cells (HLE-B3)

Correlative light and X-ray tomography jointly unveil the critical role of connexin43 channels on inflammation-induced cellular ultrastructural alterations

Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice

The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels

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