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Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools

Frontiers in immunology, 2020-04, Vol.11, p.442-442

2020

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Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy

Expert review of vaccines, 2022-02, Vol.21 (2), p.173-184

2022

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Neoadjuvant personalized cancer vaccines: the final frontier?

Expert review of vaccines, 2024, Vol.23 (1), p.205-212

2024

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Does human homology reduce the potential immunogenicity of non-antibody scaffolds?

Frontiers in immunology, 2023, Vol.14, p.1215939-1215939

2023

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In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies

mAbs, 2024, Vol.16 (1), p.2333729-2333729

2024

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Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

Scientific reports, 2021-05, Vol.11 (1), p.9983-9983, Article 9983

2021

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Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods

Frontiers in pharmacology, 2024-08, Vol.15, p.1363139

2024

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A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines

Scientific reports, 2017-04, Vol.7 (1), p.1283-11, Article 1283

2017

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In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model

PloS one, 2016-07, Vol.11 (7), p.e0159237-e0159237

2016

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Identification of immunodominant T cell epitopes induced by natural Zika virus infection

Frontiers in immunology, 2023-08, Vol.14, p.1247876

2023

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Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine

Frontiers in immunology, 2019-02, Vol.10, p.207-207

2019

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New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand

Frontiers in immunology, 2020-10, Vol.11, p.563362-563362

2020

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Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease

Frontiers in immunology, 2021-06, Vol.12, p.636731-636731

2021

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Modeling of the Hydrologic Performance of Distributed LID Stormwater under a Changing Climate: Municipal-Scale Performance Improvements

Journal of sustainable water in the built environment, 2023-05, Vol.9 (2)

2023

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In silico identification and modification of T cell epitopes in pertussis antigens associated with tolerance

Human vaccines & immunotherapeutics, 2020-02, Vol.16 (2), p.277-285

2020

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Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization

Frontiers in immunology, 2021-07, Vol.12, p.690348-690348

2021

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A physics-based routing model for modular green roof systems

Proceedings of the Institution of Civil Engineers. Water management, 2020-06, Vol.173 (3), p.142-151

2020

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Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse Plasmodium falciparum Strains

Frontiers in immunology, 2021-06, Vol.12, p.689920-689920

2021

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Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi

Human vaccines & immunotherapeutics, 2020-02, Vol.16 (2), p.214-227

2020

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Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method

BMC bioinformatics, 2015-09, Vol.16 (1), p.290-290, Article 290

2015

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Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

Frontiers in immunology, 2021-05, Vol.12, p.684116-684116

2021

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Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods

PloS one, 2014-04, Vol.9 (4), p.e94974-e94974

2014

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Immunogenicity risk assessment of synthetic peptide drugs and their impurities

Drug discovery today, 2023-10, Vol.28 (10), p.103714-103714, Article 103714

2023

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Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice

PloS one, 2014-08, Vol.9 (8), p.e104606-e104606

2014

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An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

Human vaccines & immunotherapeutics, 2017-12, Vol.13 (12), p.2824-2836

2017

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Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools

Neoantigen-based personalized cancer vaccines: the emergence of precision cancer immunotherapy

Neoadjuvant personalized cancer vaccines: the final frontier?

Does human homology reduce the potential immunogenicity of non-antibody scaffolds?

In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies

Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

Assessing the immunogenicity risk of salmon calcitonin peptide impurities using in silico and in vitro methods

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines

In Vivo Validation of Predicted and Conserved T Cell Epitopes in a Swine Influenza Model

Identification of immunodominant T cell epitopes induced by natural Zika virus infection

Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine

New Immunoinformatics Tools for Swine: Designing Epitope-Driven Vaccines, Predicting Vaccine Efficacy, and Making Vaccines on Demand

Immune Tolerance-Adjusted Personalized Immunogenicity Prediction for Pompe Disease

Modeling of the Hydrologic Performance of Distributed LID Stormwater under a Changing Climate: Municipal-Scale Performance Improvements

In silico identification and modification of T cell epitopes in pertussis antigens associated with tolerance

Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization

A physics-based routing model for modular green roof systems

Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse Plasmodium falciparum Strains

Immune escape and immune camouflage may reduce the efficacy of RTS,S vaccine in Malawi

Development and validation of an epitope prediction tool for swine (PigMatrix) based on the pocket profile method

Identification, Selection and Immune Assessment of Liver Stage CD8 T Cell Epitopes From Plasmodium falciparum

Human immune responses to H. pylori HLA Class II epitopes identified by immunoinformatic methods

Immunogenicity risk assessment of synthetic peptide drugs and their impurities

Dendritic cell-mediated, DNA-based vaccination against hepatitis C induces the multi-epitope-specific response of humanized, HLA transgenic mice

An immunoinformatics-derived DNA vaccine encoding human class II T cell epitopes of Ebola virus, Sudan virus, and Venezuelan equine encephalitis virus is immunogenic in HLA transgenic mice

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