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Channeling a complex question

Nature chemical biology, 2020-09, Vol.16 (9), p.935

St Maurice, Martin

2020

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Structure, mechanism and regulation of pyruvate carboxylase

Biochemical journal, 2008-08, Vol.413 (3), p.369-387

2008

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Solving the Conundrum: Widespread Proteins Annotated for Urea Metabolism in Bacteria Are Carboxyguanidine Deiminases Mediating Nitrogen Assimilation from Guanidine

Biochemistry (Easton), 2020-09, Vol.59 (35), p.3258-3270

2020

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Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors

Pharmaceuticals (Basel, Switzerland), 2024-05, Vol.17 (5), p.570

2024

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Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase

Biochemistry (Easton), 2022-09, Vol.61 (17), p.1824-1835

2022

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Chronic pain patients' perspectives of medical cannabis

Pain (Amsterdam), 2017-07, Vol.158 (7), p.1373-1379

2017

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Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center

Biochemistry (Easton), 2020-08, Vol.59 (33), p.3026-3037

2020

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Allosteric regulation alters carrier domain translocation in pyruvate carboxylase

Nature communications, 2018-04, Vol.9 (1), p.1384-13, Article 1384

2018

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The Structure of Allophanate Hydrolase from Granulibacter bethesdensis Provides Insights into Substrate Specificity in the Amidase Signature Family

Biochemistry (Easton), 2013-01, Vol.52 (4), p.690-700

2013

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Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs

Biochemical and biophysical research communications, 2013-11, Vol.441 (2), p.377-382

2013

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A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase

The Journal of biological chemistry, 2013-07, Vol.288 (27), p.19915-19925

2013

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The enzymes of biotin dependent CO2 metabolism: What structures reveal about their reaction mechanisms

Protein science, 2012-11, Vol.21 (11), p.1597-1619

2012

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A high-throughput screening assay for pyruvate carboxylase

Analytical biochemistry, 2018-06, Vol.550, p.90-98

2018

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Domain Architecture of Pyruvate Carboxylase, a Biotin-Dependent Multifunctional Enzyme

Science (American Association for the Advancement of Science), 2007-08, Vol.317 (5841), p.1076-1079

2007

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Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase

ACS medicinal chemistry letters, 2024-07, Vol.15 (7), p.1088-1093

2024

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The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent

Protein science, 2016-10, Vol.25 (10), p.1812-1824

2016

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A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex

The Journal of cell biology, 2012-11, Vol.199 (4), p.639-651

2012

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Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase

Biochemistry (Easton), 2023-09, Vol.62 (17), p.2632-2644

2023

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Examination of the Catalytic Role of the Axial Cystine Ligand in the Co-Type Nitrile Hydratase from Pseudonocardia thermophila JCM 3095

Catalysts, 2021-11, Vol.11 (11), p.1381

2021

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Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course

CBE life sciences education, 2014-06, Vol.13 (2), p.311-321

2014

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Slow-Onset, Potent Inhibition of Mandelate Racemase by 2‑Formylphenylboronic Acid. An Unexpected Adduct Clasps the Catalytic Machinery

Biochemistry (Easton), 2021-08, Vol.60 (32), p.2508-2518

2021

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Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni

Journal of Bacteriology, 2007-07, Vol.189 (13), p.4764-4773

2007

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Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity

Archives of biochemistry and biophysics, 2014-02, Vol.544, p.75-86

2014

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The role of biotin and oxamate in the carboxyltransferase reaction of pyruvate carboxylase

Archives of biochemistry and biophysics, 2014-11, Vol.562, p.70-79

2014

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Potent Inhibition of Mandelate Racemase by a Fluorinated Substrate-Product Analogue with a Novel Binding Mode

Biochemistry (Easton), 2014-02, Vol.53 (7), p.1169-1178

2014

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Channeling a complex question

Structure, mechanism and regulation of pyruvate carboxylase

Solving the Conundrum: Widespread Proteins Annotated for Urea Metabolism in Bacteria Are Carboxyguanidine Deiminases Mediating Nitrogen Assimilation from Guanidine

Synthesis and Evaluation of 5-(Heteroarylmethylene)hydantoins as Glycogen Synthase Kinase-3β Inhibitors

Conformational Selection Governs Carrier Domain Positioning in Staphylococcus aureus Pyruvate Carboxylase

Chronic pain patients' perspectives of medical cannabis

Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center

Allosteric regulation alters carrier domain translocation in pyruvate carboxylase

The Structure of Allophanate Hydrolase from Granulibacter bethesdensis Provides Insights into Substrate Specificity in the Amidase Signature Family

Insights into the carboxyltransferase reaction of pyruvate carboxylase from the structures of bound product and intermediate analogs

A Substrate-induced Biotin Binding Pocket in the Carboxyltransferase Domain of Pyruvate Carboxylase

The enzymes of biotin dependent CO2 metabolism: What structures reveal about their reaction mechanisms

A high-throughput screening assay for pyruvate carboxylase

Domain Architecture of Pyruvate Carboxylase, a Biotin-Dependent Multifunctional Enzyme

Synthesis and Evaluation of 1,3-Disubstituted Imidazolidine-2,4,5-triones as Inhibitors of Pyruvate Carboxylase

The urea carboxylase and allophanate hydrolase activities of urea amidolyase are functionally independent

A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex

Allosteric Site at the Biotin Carboxylase Dimer Interface Mediates Activation and Inhibition in Staphylococcus aureus Pyruvate Carboxylase

Examination of the Catalytic Role of the Axial Cystine Ligand in the Co-Type Nitrile Hydratase from Pseudonocardia thermophila JCM 3095

Writing Assignments with a Metacognitive Component Enhance Learning in a Large Introductory Biology Course

Slow-Onset, Potent Inhibition of Mandelate Racemase by 2‑Formylphenylboronic Acid. An Unexpected Adduct Clasps the Catalytic Machinery

Flavodoxin:Quinone Reductase (FqrB): a Redox Partner of Pyruvate:Ferredoxin Oxidoreductase That Reversibly Couples Pyruvate Oxidation to NADPH Production in Helicobacter pylori and Campylobacter jejuni

Functionally diverse biotin-dependent enzymes with oxaloacetate decarboxylase activity

The role of biotin and oxamate in the carboxyltransferase reaction of pyruvate carboxylase

Potent Inhibition of Mandelate Racemase by a Fluorinated Substrate-Product Analogue with a Novel Binding Mode

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