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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4462-4475

2016

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Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

Organic letters, 2011-01, Vol.13 (2), p.320-323

2011

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Drugging an undruggable pocket on KRAS

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (32), p.15823-15829

2019

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Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition

Nature chemical biology, 2016-09, Vol.12 (9), p.672-679

2016

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Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays

Journal of medicinal chemistry, 2024-07, Vol.67 (14), p.11701-11711

2024

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Development of fluorination methods using continuous-flow microreactors

Tetrahedron, 2009-08, Vol.65 (33), p.6611-6625

2009

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KRAS Binders Hidden in Nature

Chemistry : a European journal, 2019-09, Vol.25 (52), p.12037-12041

2019

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Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments

ChemMedChem, 2023-03, Vol.18 (6), p.e202200686-n/a

2023

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KRAS Binders Hidden in Nature

Chemistry : a European journal, 2019-09, Vol.25 (52), p.12002-12002

2019

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REPLY TO TRAN ET AL: Dimeric KRAS protein–protein interaction stabilizers

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (7), p.3365-3367

2020

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Abstract LB-206: A bromodomain-swap allele demonstrates that on-target chemical inhibition of BRD9 limits the proliferation of acute myeloid leukemia cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.LB-206-LB-206

2016

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(±)-trans,cis-4-Hydroxy-5,6-di-O-isopropylidenecyclohex-2-ene-1-one: Synthesis and Facile Dimerization to Decahydrodibenzofurans

Journal of organic chemistry, 2011-03, Vol.76 (5), p.1483-1486

2011

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A strategy for isotope containment during radiosynthesis--devolatilisation of bromobenzene by fluorous-tagging-Ir-catalysed borylation en route to the 4-phenylpiperidine pharmacophore

Organic & biomolecular chemistry, 2008-01, Vol.6 (22), p.4093-4095

2008

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Cis and Trans Selective 1,4-Addition of a Lithium Dithioester Enolate to 4-O-TBS-2-cyclohexenone

Organic letters, 2006-08, Vol.8 (18), p.3891-3894

2006

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Front Cover: KRAS Binders Hidden in Nature (Chem. Eur. J. 52/2019)

Chemistry : a European journal, 2019-09, Vol.25 (52), p.11998-11998

2019

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Abstract 5769: Target identification of T-cell activating immunomodulatory tetrahydrothiazepines: DGKα and DGKζ inhibitors

Cancer research (Chicago, Ill.), 2024-03, Vol.84 (6_Supplement), p.5769-5769

2024

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Opportunities for isotopic labelling via phase-tagged synthesis with organogermanium linkers

Journal of labelled compounds & radiopharmaceuticals, 2007-04, Vol.50 (5-6), p.281-285

2007

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The devolatilization of [14C]-labelled aromatics towards the synthesis of [14C]-labelled NK antagonists for PK studies

Journal of labelled compounds & radiopharmaceuticals, 2007-04, Vol.50 (5-6), p.607-608

2007

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Development of fluorination methods using continuous-flow microreactors: 2008 Tetrahedron Prize for Creativity in Organic Chemistry. The Art of Synthesis: Methods, Strategies and Applications

Tetrahedron, 2009, Vol.65 (33)

2009

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ChemInform Abstract: Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

ChemInform, 2011-04, Vol.42 (16), p.no-no

2011

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ChemInform Abstract: Development of Fluorination Methods Using Continuous-Flow Microreactors

ChemInform, 2009-12, Vol.40 (51), p.no-no

2009

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High-resolution spatiotemporal transcriptome mapping of tomato fruit development and ripening

Nature communications, 2018-01, Vol.9 (1), p.364-13, Article 364

2018

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Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree

Science (American Association for the Advancement of Science), 2023-03, Vol.379 (6638), p.1252-1264

2023

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Physical Activity Reduces Systemic Blood Pressure and Improves Early Markers of Atherosclerosis in Pre-Pubertal Obese Children

Journal of the American College of Cardiology, 2009-12, Vol.54 (25), p.2396-2406

2009

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The identification of cutin synthase: formation of the plant polyester cutin

Nature chemical biology, 2012-07, Vol.8 (7), p.609-611

2012

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Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor

Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

Drugging an undruggable pocket on KRAS

Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition

Chasing Red Herrings: Palladium Metal Salt Impurities Feigning KRAS Activity in Biochemical Assays

Development of fluorination methods using continuous-flow microreactors

KRAS Binders Hidden in Nature

Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments

KRAS Binders Hidden in Nature

REPLY TO TRAN ET AL: Dimeric KRAS protein–protein interaction stabilizers

Abstract LB-206: A bromodomain-swap allele demonstrates that on-target chemical inhibition of BRD9 limits the proliferation of acute myeloid leukemia cells

(±)-trans,cis-4-Hydroxy-5,6-di-O-isopropylidenecyclohex-2-ene-1-one: Synthesis and Facile Dimerization to Decahydrodibenzofurans

A strategy for isotope containment during radiosynthesis--devolatilisation of bromobenzene by fluorous-tagging-Ir-catalysed borylation en route to the 4-phenylpiperidine pharmacophore

Cis and Trans Selective 1,4-Addition of a Lithium Dithioester Enolate to 4-O-TBS-2-cyclohexenone

Front Cover: KRAS Binders Hidden in Nature (Chem. Eur. J. 52/2019)

Abstract 5769: Target identification of T-cell activating immunomodulatory tetrahydrothiazepines: DGKα and DGKζ inhibitors

Opportunities for isotopic labelling via phase-tagged synthesis with organogermanium linkers

The devolatilization of [14C]-labelled aromatics towards the synthesis of [14C]-labelled NK antagonists for PK studies

Development of fluorination methods using continuous-flow microreactors: 2008 Tetrahedron Prize for Creativity in Organic Chemistry. The Art of Synthesis: Methods, Strategies and Applications

ChemInform Abstract: Safe and Reliable Synthesis of Diazoketones and Quinoxalines in a Continuous Flow Reactor

ChemInform Abstract: Development of Fluorination Methods Using Continuous-Flow Microreactors

High-resolution spatiotemporal transcriptome mapping of tomato fruit development and ripening

Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree

Physical Activity Reduces Systemic Blood Pressure and Improves Early Markers of Atherosclerosis in Pre-Pubertal Obese Children

The identification of cutin synthase: formation of the plant polyester cutin

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