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Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers

PLoS computational biology, 2015-08, Vol.11 (8), p.e1004405-e1004405

2015

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The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity

PLoS pathogens, 2013-07, Vol.9 (7), p.e1003518

2013

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Identification of Novel Inhibitors of DLK Palmitoylation and Signaling by High Content Screening

Scientific reports, 2019-03, Vol.9 (1), p.3632-3632, Article 3632

2019

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Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

Acta neuropathologica communications, 2018-03, Vol.6 (1), p.16-16, Article 16

2018

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Fatty links between multisystem proteinopathy and small VCP-interacting protein

Cell death discovery, 2024-08, Vol.10 (1), p.358-14, Article 358

2024

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Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog

The FASEB journal, 2008-03, Vol.22 (3), p.797-806

2008

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Altered Protein Palmitoylation as Disease Mechanism in Neurodegenerative Disorders

The Journal of neuroscience, 2024-10, Vol.44 (40), p.e1225242024

2024

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Lost in traffic: consequences of altered palmitoylation in neurodegeneration

Frontiers in physiology, 2023-05, Vol.14, p.1166125-1166125

2023

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Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage

Frontiers in physiology, 2023-01, Vol.14, p.1086112-1086112

2023

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Protective Proteolysis in Huntington’s Disease: Unraveling the Role of Post-Translational Myristoylation of Huntingtin in Autophagy

Journal of Huntington's disease, 2024-01, Vol.13 (3), p.267-277

2024

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Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin

Human molecular genetics, 2014-06, Vol.23 (12), p.3166-3179

2014

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Neurodegeneration: Role of repeats in protein clearance

Nature (London), 2017-05, Vol.545 (7652), p.33-34

2017

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Autophagy in Huntington disease and huntingtin in autophagy

Trends in neurosciences (Regular ed.), 2015-01, Vol.38 (1), p.26-35

2015

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human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes

Proceedings of the National Academy of Sciences - PNAS, 2009-07, Vol.106 (30), p.12365-12370

2009

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Let's get fat: emergence of S -acylation as a therapeutic target in Huntington disease

Biochemical Society transactions, 2024-06, Vol.52 (3), p.1385-1392

2024

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Post-translational myristoylation: Fat matters in cellular life and death

Biochimie, 2011, Vol.93 (1), p.18-31

2011

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Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance

The FASEB journal, 2019-03, Vol.33 (3), p.3190-3197

2019

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Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks

Journal of controlled release, 2023-08, Vol.360, p.913-927

2023

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Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease

Journal of controlled release, 2024-03, Vol.367, p.27-44

2024

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Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity

Neurobiology of disease, 2021-10, Vol.158, p.105479-105479, Article 105479

2021

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Surface study of apoB1694–1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable

Journal of lipid research, 2009-07, Vol.50 (7), p.1340-1352

2009

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Role of repeats in protein clearance

Nature (London), 2017-05, Vol.545 (7652), p.33-34

2017

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Structure−Function Studies of Human Apolipoprotein A-V: A Regulator of Plasma Lipid Homeostasis

Biochemistry (Easton), 2003-08, Vol.42 (31), p.9416-9423

2003

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Post-translational myristoylation at the cross roads of cell death, autophagy and neurodegeneration

Biochemical Society transactions, 2015-04, Vol.43 (2), p.229-234

2015

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Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry[S]

Journal of lipid research, 2010-06, Vol.51 (6), p.1566-1580

2010

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Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers

The Salmonella type III effector SspH2 specifically exploits the NLR co-chaperone activity of SGT1 to subvert immunity

Identification of Novel Inhibitors of DLK Palmitoylation and Signaling by High Content Screening

Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease

Fatty links between multisystem proteinopathy and small VCP-interacting protein

Rapid detection, discovery, and identification of post-translationally myristoylated proteins during apoptosis using a bio-orthogonal azidomyristate analog

Altered Protein Palmitoylation as Disease Mechanism in Neurodegenerative Disorders

Lost in traffic: consequences of altered palmitoylation in neurodegeneration

Full-length huntingtin is palmitoylated at multiple sites and post-translationally myristoylated following caspase-cleavage

Protective Proteolysis in Huntington’s Disease: Unraveling the Role of Post-Translational Myristoylation of Huntingtin in Autophagy

Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin

Neurodegeneration: Role of repeats in protein clearance

Autophagy in Huntington disease and huntingtin in autophagy

human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes

Let's get fat: emergence of S -acylation as a therapeutic target in Huntington disease

Post-translational myristoylation: Fat matters in cellular life and death

Identification of a novel caspase cleavage site in huntingtin that regulates mutant huntingtin clearance

Delivery of mutant huntingtin-lowering antisense oligonucleotides to the brain by intranasally administered apolipoprotein A-I nanodisks

Systemic delivery of mutant huntingtin lowering antisense oligonucleotides to the brain using apolipoprotein A-I nanodisks for Huntington disease

Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity

Surface study of apoB1694–1880, a sequence that can anchor apoB to lipoproteins and make it nonexchangeable

Role of repeats in protein clearance

Structure−Function Studies of Human Apolipoprotein A-V: A Regulator of Plasma Lipid Homeostasis

Post-translational myristoylation at the cross roads of cell death, autophagy and neurodegeneration

Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry[S]

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