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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

Leukemia, 2009-01, Vol.23 (1), p.25-42

2009

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Clusterin enhances AKT2‐mediated motility of normal and cancer prostate cells through a PTEN and PHLPP1 circuit

Journal of cellular physiology, 2019-07, Vol.234 (7), p.11188-11199

2019

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CTLA‐4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction

International journal of cancer, 2005-11, Vol.117 (4), p.538-550

2005

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A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

Leukemia, 2003-09, Vol.17 (9), p.1794-1805

2003

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The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system

BBA - Molecular and Cell Biology of Lipids, 2002-10, Vol.1584 (2), p.73-80

2002

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Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients

Leukemia, 2006-02, Vol.20 (2), p.230-238

2006

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Nuclear inositides: facts and perspectives

Pharmacology & therapeutics (Oxford), 2004-01, Vol.101 (1), p.47-64

2004

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Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells

Journal of cellular physiology, 2005-02, Vol.202 (2), p.623-634

2005

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Nuclear phospholipase C: Involvement in signal transduction

Progress in lipid research, 2005-07, Vol.44 (4), p.185-206

2005

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Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

British journal of haematology, 2005-06, Vol.129 (5), p.677-686

2005

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Metabolism and signaling activities of nuclear lipids

Cellular and molecular life sciences : CMLS, 2004-05, Vol.61 (10), p.1143-1156

2004

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Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells

Journal of cellular physiology, 2006-06, Vol.207 (3), p.836-844

2006

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Nuclear apoptotic changes: An overview

Journal of cellular biochemistry, 2001-01, Vol.82 (4), p.634-646

2001

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RELATIONSHIPS BETWEEN PHENOLIC COMPOSITION OF OLIVE FRUIT AND OLIVE OIL: THE IMPORTANCE OF THE ENDOGENOUS ENZYMES

Acta horticulturae, 2002 (586), p.551-556

2002

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Diacylglycerol kinase-θ is localized in the speckle domains of the nucleus

Experimental cell research, 2003-07, Vol.287 (1), p.143-154

2003

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Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors

FEBS letters, 2000-07, Vol.477 (1), p.27-32

2000

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Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-κB activation and cFLIP up-regulation

Leukemia, 2003-02, Vol.17 (2), p.379-389

2003

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Phosphoinositide 3‐kinase/Akt inhibition increases arsenic trioxide‐induced apoptosis of acute promyelocytic and T‐cell leukaemias

British journal of haematology, 2005-09, Vol.130 (5), p.716-725

2005

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Nuclear inositol lipid metabolism: More than just second messenger generation?

Journal of cellular biochemistry, 2005-10, Vol.96 (2), p.285-292

2005

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Threonine 308 phosphorylated form of akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin

Journal of cellular physiology, 2003-07, Vol.196 (1), p.79-88

2003

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Nuclear protein kinase C isoforms and apoptosis

European journal of histochemistry, 2004-01, Vol.48 (1), p.89-94

2004

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Nuclear Diacylglycerol Produced by Phosphoinositide-specific Phospholipase C Is Responsible for Nuclear Translocation of Protein Kinase C-α

The Journal of biological chemistry, 1998-11, Vol.273 (45), p.29738-29744

1998

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The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells

Molecular cancer research, 2003, Vol.1 (3), p.234-246

2003

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Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation

Journal of cellular physiology, 2004-08, Vol.200 (2), p.291-296

2004

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Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells

Nature (London), 1992-07, Vol.358 (6383), p.242-245

1992

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Targeting the leukemic stem cell: the Holy Grail of leukemia therapy

Clusterin enhances AKT2‐mediated motility of normal and cancer prostate cells through a PTEN and PHLPP1 circuit

CTLA‐4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system

Frequent elevation of Akt kinase phosphorylation in blood marrow and peripheral blood mononuclear cells from high-risk myelodysplastic syndrome patients

Nuclear inositides: facts and perspectives

Phosphoinositide 3-kinase/Akt involvement in arsenic trioxide resistance of human leukemia cells

Nuclear phospholipase C: Involvement in signal transduction

Deguelin, A PI3K/AKT inhibitor, enhances chemosensitivity of leukaemia cells with an active PI3K/AKT pathway

Metabolism and signaling activities of nuclear lipids

Caspase-dependent cleavage of 170-kDa P-glycoprotein during apoptosis of human T-lymphoblastoid CEM cells

Nuclear apoptotic changes: An overview

RELATIONSHIPS BETWEEN PHENOLIC COMPOSITION OF OLIVE FRUIT AND OLIVE OIL: THE IMPORTANCE OF THE ENDOGENOUS ENZYMES

Diacylglycerol kinase-θ is localized in the speckle domains of the nucleus

Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors

Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-κB activation and cFLIP up-regulation

Phosphoinositide 3‐kinase/Akt inhibition increases arsenic trioxide‐induced apoptosis of acute promyelocytic and T‐cell leukaemias

Nuclear inositol lipid metabolism: More than just second messenger generation?

Threonine 308 phosphorylated form of akt translocates to the nucleus of PC12 cells under nerve growth factor stimulation and associates with the nuclear matrix protein nucleolin

Nuclear protein kinase C isoforms and apoptosis

Nuclear Diacylglycerol Produced by Phosphoinositide-specific Phospholipase C Is Responsible for Nuclear Translocation of Protein Kinase C-α

The phosphoinositide 3-kinase/AKT1 pathway involvement in drug and all-trans-retinoic acid resistance of leukemia cells

Expression of phospholipase C beta family isoenzymes in C2C12 myoblasts during terminal differentiation

Nuclear localization and signalling activity of phosphoinositidase Cβ in Swiss 3T3 cells

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