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Discovery and Structure–Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions

Journal of medicinal chemistry, 2016-04, Vol.59 (7), p.2962-2972

2016

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Insights on Structure–Passive Permeability Relationship in Pyrrole and Furan-Containing Macrocycles

Journal of medicinal chemistry, 2024-03, Vol.67 (5), p.3711-3726

2024

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Macrocyclic Cell Penetrating Peptides: A Study of Structure-Penetration Properties

Bioconjugate chemistry, 2015-03, Vol.26 (3), p.405-411

2015

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C‑Terminal Modifications of Apelin-13 Significantly Change Ligand Binding, Receptor Signaling, and Hypotensive Action

Journal of medicinal chemistry, 2015-03, Vol.58 (5), p.2431-2440

2015

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Modulation of the Passive Permeability of Semipeptidic Macrocycles: N- and C‑Methylations Fine-Tune Conformation and Properties

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5365-5383

2021

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The apelinergic system as an alternative to catecholamines in low-output septic shock

Critical care (London, England), 2018-01, Vol.22 (1), p.10-10, Article 10

2018

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Size-Reduced Macrocyclic Analogues of [Pyr1]‑apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.531-551

2022

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A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2266-2277

2018

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Constraining the Side Chain of C‑Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5345-5364

2021

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Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8–13)

Journal of medicinal chemistry, 2018-08, Vol.61 (16), p.7103-7115

2018

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Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid

Biopolymers, 2014-07, Vol.102 (4), p.297-303

2014

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Tomatidine Inhibits Replication of Staphylococcus aureus Small-Colony Variants in Cystic Fibrosis Airway Epithelial Cells

Antimicrobial Agents and Chemotherapy, 2011-05, Vol.55 (5), p.1937-1945

2011

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Bis-Michael Acceptors as Novel Probes to Study the Keap1/Nrf2/ARE Pathway

Journal of medicinal chemistry, 2016-10, Vol.59 (20), p.9431-9442

2016

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Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery

Journal of medicinal chemistry, 2011-04, Vol.54 (7), p.1961-2004

2011

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Modular sub-monomeric cell-penetrating guanidine-rich peptoids – synthesis, assembly and biological evaluation

RSC advances, 2017, Vol.7 (10), p.6059-6063

2017

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In Search of the Optimal Macrocyclization Site for Neurotensin

ACS medicinal chemistry letters, 2018-03, Vol.9 (3), p.227-232

2018

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Structure–Activity Relationship and Signaling of New Chimeric CXCR4 Agonists

Journal of medicinal chemistry, 2016-08, Vol.59 (16), p.7512-7524

2016

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Simultaneous Ligand and Receptor Tracking through NMR Spectroscopy Enabled by Distinct 19F Labels

International journal of molecular sciences, 2019-07, Vol.20 (15), p.3658

2019

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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

Nature (London), 2022-05, Vol.605 (7909), p.340-348

2022

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Localized apelin-17 analogue-bicelle interactions as a facilitator of membrane-catalyzed receptor recognition and binding

Biochimica et biophysica acta. Biomembranes, 2024-03, Vol.1866 (3), p.184289, Article 184289

2024

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Discovery of a CCR2-targeting pepducin therapy for chronic pain

Pharmacological research, 2024-07, Vol.205, p.107242, Article 107242

2024

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ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock

Critical care medicine, 2017-11, Vol.45 (11), p.e1139-e1148

2017

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Une nouvelle classe de macromolécules polycationiques à l’assaut des pathogènes multirésistants

M.S. Médecine sciences, 2018-10, Vol.34 (10), p.791-795

Marsault, Éric

2018

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Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C

Antimicrobial agents and chemotherapy, 2018-06, Vol.62 (6)

2018

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Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes

Cell chemical biology, 2019-11, Vol.26 (11), p.1559-1572.e9

2019

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Discovery and Structure–Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions

Insights on Structure–Passive Permeability Relationship in Pyrrole and Furan-Containing Macrocycles

Macrocyclic Cell Penetrating Peptides: A Study of Structure-Penetration Properties

C‑Terminal Modifications of Apelin-13 Significantly Change Ligand Binding, Receptor Signaling, and Hypotensive Action

Modulation of the Passive Permeability of Semipeptidic Macrocycles: N- and C‑Methylations Fine-Tune Conformation and Properties

The apelinergic system as an alternative to catecholamines in low-output septic shock

Size-Reduced Macrocyclic Analogues of [Pyr1]‑apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects

A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects

Constraining the Side Chain of C‑Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile

Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8–13)

Stability and degradation patterns of chemically modified analogs of apelin-13 in plasma and cerebrospinal fluid

Tomatidine Inhibits Replication of Staphylococcus aureus Small-Colony Variants in Cystic Fibrosis Airway Epithelial Cells

Bis-Michael Acceptors as Novel Probes to Study the Keap1/Nrf2/ARE Pathway

Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery

Modular sub-monomeric cell-penetrating guanidine-rich peptoids – synthesis, assembly and biological evaluation

In Search of the Optimal Macrocyclization Site for Neurotensin

Structure–Activity Relationship and Signaling of New Chimeric CXCR4 Agonists

Simultaneous Ligand and Receptor Tracking through NMR Spectroscopy Enabled by Distinct 19F Labels

A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

Localized apelin-17 analogue-bicelle interactions as a facilitator of membrane-catalyzed receptor recognition and binding

Discovery of a CCR2-targeting pepducin therapy for chronic pain

ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock

Une nouvelle classe de macromolécules polycationiques à l’assaut des pathogènes multirésistants

Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C

Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes

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