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The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Molecular and Cellular Biology, 2000-11, Vol.20 (22), p.8513-8525

2000

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Snake venom serine proteinases: sequence homology vs. substrate specificity, a paradox to be solved

Toxicon (Oxford), 2005-06, Vol.45 (8), p.1115-1132

2005

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Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

Nature (London), 1990-09, Vol.347 (6290), p.286-289

1990

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Identification of the substrate-binding exosites of two snake venom serine proteinases: molecular basis for the partition of two essential functions of thrombin

Journal of molecular recognition, 2004-01, Vol.17 (1), p.51-61

2004

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The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Molecular and Cellular Biology, 1999-03, Vol.19 (3), p.1784-1799

1999

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Distinct roles for CD4 and CD8 as co‐receptors in T cell receptor signalling

European journal of immunology, 1994-04, Vol.24 (4), p.959-966

1994

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A Conserved Inositol Phospholipid Binding Site within the Pleckstrin Homology Domain of the Gab1 Docking Protein Is Required for Epithelial Morphogenesis

The Journal of biological chemistry, 1999-10, Vol.274 (44), p.31719-31726

1999

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Distinct involvement of CD45 in antigen receptor signalling in CD4+ and CD8+ primary T cells

European journal of immunology, 1994-04, Vol.24 (4), p.967-973

1994

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Toxicity evolution of Vipera aspis aspis venom: identification and molecular modeling of a novel phospholipase A(2) heterodimer neurotoxin

FEBS letters, 2002-09, Vol.527 (1-3), p.263

2002

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The Gab1 Docking Protein Links the B Cell Antigen Receptor to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and to the SHP2 Tyrosine Phosphatase

The Journal of biological chemistry, 2001-04, Vol.276 (15), p.12257-12265

2001

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Structural Basis of the gp120 Superantigen-Binding Site on Human Immunoglobulins

The Journal of immunology (1950), 1998-12, Vol.161 (12), p.6681-6688

1998

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Entamoeba histolytica: inhibition of cellular functions by overexpression of EhGEF1, a novel Rho/Rac guanine nucleotide exchange factor

Experimental parasitology, 2005-03, Vol.109 (3), p.150-162

2005

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Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion

Molecular biology of the cell, 2000-10, Vol.11 (10), p.3397-3410

2000

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Trimeresurus stejnegeri snake venom plasminogen activator. Site-directed mutagenesis and molecular modeling

The Journal of biological chemistry, 1997-08, Vol.272 (33), p.20531-20537

1997

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Induction of DNA bending by bifunctional intercalating agents of the 7H-pyridocarbazole family

Biophysical chemistry, 1991, Vol.39 (1), p.45-56

1991

Volltextzugriff (PDF)

Physical Association of CD4 and CD45 in Primary, Resting CD4+T Cells

Cellular immunology, 1997-01, Vol.175 (1), p.1-11

1997

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Molecular basis for the partition of the essential functions of thrombin among snake venom serine proteinases: the case of thrombin-like enzymes

Haemostasis, 2001-05, Vol.31 (3-6), p.247-256

Maroun, R C

2001

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Potent preclinical antitumor activity of MGCD265, an oral Met/VEGFR kinase inhibitor in phase II clinical development, in combination with taxanes or erlotinib

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.e13595-e13595

2010

Volltextzugriff (PDF)

Molecular Modeling of an Active Loop Structure in Lysozyme. Sequence Effects or Crystal Packing?

Journal of biomolecular structure & dynamics, 1999-02, Vol.16 (4), p.873-889

Maroun, Rachid C.

1999

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A phase I study of oral administration of MGCD265 in patients with advanced malignancies (study 265-102)

Journal of clinical oncology, 2010-05, Vol.28 (15_suppl), p.3108-3108

2010

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MGCD265, an oral Met/VEGFR multitargeted receptor tyrosine kinase inhibitor, in combination with erlotinib: Phase I clinical experience

Journal of clinical oncology, 2011-05, Vol.29 (15_suppl), p.3083-3083

2011

Volltextzugriff (PDF)

Determination of the maximum tolerated dose (MTD) of MGCD265, an oral Met/VEGFR multitargeted receptor tyrosine kinase inhibitor, in combination with docetaxel

Journal of clinical oncology, 2011-05, Vol.29 (15_suppl), p.3032-3032

2011

Volltextzugriff (PDF)

Identification and molecular structural prediction analysis of a toxicity determinant in the Bacillus sphaericus crystal larvicidal toxin

European Journal of Biochemistry, 2001-05, Vol.268 (9), p.2751-2760

2001

Volltextzugriff (PDF)

Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling

Immunology today (Amsterdam. Regular ed.), 1993-04, Vol.14 (4), p.177-183

1993

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Combining phage display and molecular modeling to map the epitope of a neutralizing antitoxin antibody

European journal of biochemistry, 2000-04, Vol.267 (8), p.2345-2353

2000

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The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Snake venom serine proteinases: sequence homology vs. substrate specificity, a paradox to be solved

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

Identification of the substrate-binding exosites of two snake venom serine proteinases: molecular basis for the partition of two essential functions of thrombin

The Gab1 PH Domain Is Required for Localization of Gab1 at Sites of Cell-Cell Contact and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase

Distinct roles for CD4 and CD8 as co‐receptors in T cell receptor signalling

A Conserved Inositol Phospholipid Binding Site within the Pleckstrin Homology Domain of the Gab1 Docking Protein Is Required for Epithelial Morphogenesis

Distinct involvement of CD45 in antigen receptor signalling in CD4+ and CD8+ primary T cells

Toxicity evolution of Vipera aspis aspis venom: identification and molecular modeling of a novel phospholipase A(2) heterodimer neurotoxin

The Gab1 Docking Protein Links the B Cell Antigen Receptor to the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and to the SHP2 Tyrosine Phosphatase

Structural Basis of the gp120 Superantigen-Binding Site on Human Immunoglobulins

Entamoeba histolytica: inhibition of cellular functions by overexpression of EhGEF1, a novel Rho/Rac guanine nucleotide exchange factor

Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion

Trimeresurus stejnegeri snake venom plasminogen activator. Site-directed mutagenesis and molecular modeling

Induction of DNA bending by bifunctional intercalating agents of the 7H-pyridocarbazole family

Physical Association of CD4 and CD45 in Primary, Resting CD4+T Cells

Molecular basis for the partition of the essential functions of thrombin among snake venom serine proteinases: the case of thrombin-like enzymes

Potent preclinical antitumor activity of MGCD265, an oral Met/VEGFR kinase inhibitor in phase II clinical development, in combination with taxanes or erlotinib

Molecular Modeling of an Active Loop Structure in Lysozyme. Sequence Effects or Crystal Packing?

A phase I study of oral administration of MGCD265 in patients with advanced malignancies (study 265-102)

MGCD265, an oral Met/VEGFR multitargeted receptor tyrosine kinase inhibitor, in combination with erlotinib: Phase I clinical experience

Determination of the maximum tolerated dose (MTD) of MGCD265, an oral Met/VEGFR multitargeted receptor tyrosine kinase inhibitor, in combination with docetaxel

Identification and molecular structural prediction analysis of a toxicity determinant in the Bacillus sphaericus crystal larvicidal toxin

Distinct roles for CD4 and CD8 as co-receptors in antigen receptor signalling

Combining phage display and molecular modeling to map the epitope of a neutralizing antitoxin antibody

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