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Tumor Angiogenesis: A Key Target for Cancer Therapy

1st ed. 2019., 2019

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Migration of Human Monocytes in Response to Vascular Endothelial Growth Factor (VEGF) Is Mediated via the VEGF Receptor flt-1

Blood, 1996-04, Vol.87 (8), p.3336-3343

1996

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Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model

Cancer research (Chicago, Ill.), 2000-09, Vol.60 (17), p.4819-4824

2000

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Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials

Annals of oncology, 2005-04, Vol.16 (4), p.558-565

2005

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Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9194-9197

1993

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Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease

Cancer, 1999-01, Vol.85 (1), p.178-187

1999

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Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein

Cancer research (Chicago, Ill.), 1996-05, Vol.56 (10), p.2299-2301

1996

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Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells

Cancer research (Chicago, Ill.), 1997-12, Vol.57 (23), p.5421-5425

1997

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Two independent mechanisms essential for tumor angiogenesis : Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway

Cancer research (Chicago, Ill.), 1999-07, Vol.59 (13), p.3185-3191

1999

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Hypoxia-Induced Transcription of the Vascular Endothelial Growth Factor Gene Is Independent of Functional Ap-1 Transcription Factor

Biochemical and biophysical research communications, 1995-03, Vol.208 (1), p.432-439

1995

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Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells (∗)

The Journal of biological chemistry, 1995-10, Vol.270 (43), p.25915-25919

1995

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Protein kinase C α activates RAF-1 by direct phosphorylation

Nature (London), 1993-07, Vol.364 (6434), p.249-252

1993

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Expression of the vascular endothelial growth factor gene is inhibited by p73

Oncogene, 2000-07, Vol.19 (31), p.3470-3476

2000

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Human chorionic gonadotropin-dependent expression of vascular endothelial growth factor/vascular permeability factor in human granulosa cells: importance in ovarian hyperstimulation syndrome

The journal of clinical endocrinology and metabolism, 1995-06, Vol.80 (6), p.1967

1995

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Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression

Oncogene, 1994-03, Vol.9 (3), p.963-969

1994

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Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression

Oncogene, 1997-08, Vol.15 (6), p.669-676

1997

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Oncogenes as inducers of tumor angiogenesis

Cancer and metastasis reviews, 1995-12, Vol.14 (4), p.263-277

1995

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Oncogenes as inducers of tumor angiogenesis

Cancer and metastasis reviews, 1995-12, Vol.14 (4), p.263

1995

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The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities

Cancer and metastasis reviews, 1998-06, Vol.17 (2), p.241-248

1998

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Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1

The Journal of biological chemistry, 1997-04, Vol.272 (16), p.10382-10388

1997

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Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy

1. Aufl., 2008

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Differentiation and Definition of Vascular-Targeted Therapies

Clinical cancer research, 2005-01, Vol.11 (2), p.416-420

2005

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VEGF-mediated tumour angiogenesis: a new target for cancer therapy

Current opinion in biotechnology, 1995, Vol.6 (6), p.675-680

1995

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Go 6976, a Selective Inhibitor of Protein Kinase C, is a Potent Antagonist of Human Immunodeficiency Virus 1 Induction from Latent/Low-Level-Producing Reservoir Cells in vitro

Proceedings of the National Academy of Sciences - PNAS, 1993-05, Vol.90 (10), p.4674-4678

1993

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Tumor Angiogenesis: A Key Target for Cancer Therapy

Migration of Human Monocytes in Response to Vascular Endothelial Growth Factor (VEGF) Is Mediated via the VEGF Receptor flt-1

Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model

Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease

Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells

Two independent mechanisms essential for tumor angiogenesis : Inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway

Hypoxia-Induced Transcription of the Vascular Endothelial Growth Factor Gene Is Independent of Functional Ap-1 Transcription Factor

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells (∗)

Protein kinase C α activates RAF-1 by direct phosphorylation

Expression of the vascular endothelial growth factor gene is inhibited by p73

Human chorionic gonadotropin-dependent expression of vascular endothelial growth factor/vascular permeability factor in human granulosa cells: importance in ovarian hyperstimulation syndrome

Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression

Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression

Oncogenes as inducers of tumor angiogenesis

Oncogenes as inducers of tumor angiogenesis

The pivotal role of VEGF in tumor angiogenesis: molecular facts and therapeutic opportunities

Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1

Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy

Differentiation and Definition of Vascular-Targeted Therapies

VEGF-mediated tumour angiogenesis: a new target for cancer therapy

Go 6976, a Selective Inhibitor of Protein Kinase C, is a Potent Antagonist of Human Immunodeficiency Virus 1 Induction from Latent/Low-Level-Producing Reservoir Cells in vitro

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