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How mass spectrometry can be exploited to study AMPK

Essays in biochemistry, 2024-07

2024

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Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2019-07, Vol.1864 (7), p.1017-1030

2019

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A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle

Biochemical journal, 2012-10, Vol.447 (1), p.137-147

2012

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Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies

Nature communications, 2023-06, Vol.14 (1), p.3706-3706, Article 3706

2023

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PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

Biochemical journal, 2013-06, Vol.452 (3), p.531-543

2013

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A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

Biochemical journal, 2014-06, Vol.460 (3), p.363-375

2014

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AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Biochemical journal, 2012-04, Vol.443 (1), p.193-203

2012

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Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling

Molecular and cellular biology, 2014-11, Vol.34 (22), p.4088-4103

2014

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Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle

Cellular signalling, 2013-09, Vol.25 (9), p.1877-1886

2013

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Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

American journal of physiology: endocrinology and metabolism, 2016-10, Vol.311 (4), p.E706-E719

2016

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Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

Biochemical journal, 2012-03, Vol.442 (3), p.681-692

2012

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6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

Biochemical journal, 2004-08, Vol.381 (Pt 3), p.561-579

2004

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AMPK inhibits liver gluconeogenesis: fact or fiction?

Biochemical journal, 2023-01, Vol.480 (1), p.105-125

2023

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Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

Biochemical journal, 2013-10, Vol.455 (2), p.195-206

2013

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AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase

The Journal of biological chemistry, 2008-07, Vol.283 (27), p.18505-18512

2008

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Metabolic control by AMPK in white adipose tissue

Trends in endocrinology and metabolism, 2023-11, Vol.34 (11), p.704-717

2023

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Identification of a dehydrogenase acting on D-2-hydroxyglutarate

Biochemical journal, 2004-07, Vol.381 (Pt 1), p.35-42

2004

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Role of AMP-activated protein kinase in metabolic depression in animals

Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology, 2016, Vol.186 (1), p.1-16

Rider, Mark H.

2016

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Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (12), p.4727-4732

2008

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Identification of Phosphorylation Sites in AMP-activated Protein Kinase (AMPK) for Upstream AMPK Kinases and Study of Their Roles by Site-directed Mutagenesis

The Journal of biological chemistry, 2003-08, Vol.278 (31), p.28434-28442

2003

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Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells

FEBS letters, 2002-08, Vol.526 (1), p.38-42

2002

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Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei

Molecular and biochemical parasitology, 2008-04, Vol.158 (2), p.189-201

2008

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The synthesis of branched-chain fatty acids is limited by enzymatic decarboxylation of ethyl- and methylmalonyl-CoA

Biochemical journal, 2019-08, Vol.476 (16), p.2427-2447

2019

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Myocardial Ischemia and Increased Heart Work Modulate the Phosphorylation State of Eukaryotic Elongation Factor-2

The Journal of biological chemistry, 2003-10, Vol.278 (43), p.41970-41976

2003

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TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Nature (London), 2020-02, Vol.578 (7796), p.605-609

2020

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How mass spectrometry can be exploited to study AMPK

Saturated fatty acids induce NLRP3 activation in human macrophages through K+ efflux resulting from phospholipid saturation and Na, K-ATPase disruption

A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle

Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

Eukaryotic Elongation Factor 2 Kinase Activity Is Controlled by Multiple Inputs from Oncogenic Signaling

Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle

Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle

Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

AMPK inhibits liver gluconeogenesis: fact or fiction?

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle

AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase

Metabolic control by AMPK in white adipose tissue

Identification of a dehydrogenase acting on D-2-hydroxyglutarate

Role of AMP-activated protein kinase in metabolic depression in animals

Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis

Identification of Phosphorylation Sites in AMP-activated Protein Kinase (AMPK) for Upstream AMPK Kinases and Study of Their Roles by Site-directed Mutagenesis

Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells

Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei

The synthesis of branched-chain fatty acids is limited by enzymatic decarboxylation of ethyl- and methylmalonyl-CoA

Myocardial Ischemia and Increased Heart Work Modulate the Phosphorylation State of Eukaryotic Elongation Factor-2

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

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