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Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR genes are clinically significant predictors of fluoropyrimidine toxicity

British journal of cancer, 2013-06, Vol.108 (12), p.2505-2515

2013

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Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease

Alimentary pharmacology & therapeutics, 2010-07, Vol.32 (2), p.119-130

2010

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Novel pharmacogenetic markers for treatment outcome in azathioprine‐treated inflammatory bowel disease

Alimentary pharmacology & therapeutics, 2009-08, Vol.30 (4), p.375-384

2009

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Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

Alimentary pharmacology & therapeutics, 2007-05, Vol.25 (9), p.1069-1077

2007

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Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single-centre prospective study

British journal of dermatology (1951), 2012-07, Vol.167 (1), p.165-173

2012

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Mechanism of allopurinol induced TPMT inhibition

Biochemical pharmacology, 2013-08, Vol.86 (4), p.539-547

2013

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Genotyping before azathioprine administration in dermatology

Clinical and experimental dermatology, 2022-02, Vol.47 (2), p.503-504

2022

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unusual genetic variant in the MOCS1 gene leads to complete missplicing of an alternatively spliced exon in a patient with molybdenum cofactor deficiency

Journal of inherited metabolic disease, 2009-08, Vol.32 (4), p.560-569

2009

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The effect of pre‐operative anxiety on induction of anaesthesia with propofol

Anaesthesia, 2008-05, Vol.63 (5), p.467-473

2008

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Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations

The pharmacogenomics journal, 2014-10, Vol.14 (5), p.411-417

2014

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A practical guide to the use of thiopurines in oral medicine

Journal of oral pathology & medicine, 2015-11, Vol.44 (10), p.761-768

2015

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Do ITPA and TPMT genotypes predict the development of side effects to AZA?

Gut, 2006-07, Vol.55 (7), p.1048-1049

2006

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Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency

Human genetics, 2002-10, Vol.111 (4-5), p.360-367

2002

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Mutation in the ITPA Gene Predicts Intolerance to Azathioprine

Nucleosides, nucleotides & nucleic acids, 2004-10, Vol.23 (8-9), p.1393-1397

2004

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Deoxyuridine accumulation in urine in thymidine phosphorylase deficiency (MNGIE)

Journal of inherited metabolic disease, 2002-11, Vol.25 (7), p.603-604

2002

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HPLC/Tandem Ion Trap Mass Detector Methods for Determination of Inosine Monophosphate Dehydrogenase (IMPDH) and Thiopurine Methyltransferase (TPMT)

Nucleosides, nucleotides & nucleic acids, 2006-06, Vol.25 (9-11), p.1241-1244

2006

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Does genetic variability in aldehyde oxidase and molybdenum cofactor sulfurase predict nonresponse to allopurinol?

Alimentary pharmacology & therapeutics, 2010-07, Vol.32 (2), p.310-311

2010

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A biochemical mechanism for the role of allopurinol in TMPT inhibition

Gut, 2011-04, Vol.60 (Suppl 1), p.A132-A133

2011

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Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene

Leukemia, 2001-11, Vol.15 (11), p.1792-1793

2001

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Allele Frequency of Inosine Triphosphate Pyrophosphatase Gene Polymorphisms in a Japanese Population

Nucleosides, nucleotides & nucleic acids, 2004-10, Vol.23 (8-9), p.1399-1401

2004

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Genetic Determinants of the Pre- and Post-Azathioprine Therapy Thiopurine Methyltransferase Activity Phenotype

Nucleosides, nucleotides & nucleic acids, 2004-10, Vol.23 (8-9), p.1403-1405

2004

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Familial juvenile hyperuricaemic nephropathy

QJM : An International Journal of Medicine, 2004-02, Vol.97 (2), p.106-107

2004

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Adenylosuccinate Lyase Deficiency-First British Case

Nucleosides, nucleotides & nucleic acids, 2004-10, Vol.23 (8-9), p.1231-1233

2004

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An Unusual Pyridine Nucleotide Accumulating in Erythrocytes: Its Identity, and Positive Correlation with Degree of Renal Failure

Nucleosides, nucleotides & nucleic acids, 2004-10, Vol.23 (8-9), p.1135-1139

2004

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GTP Concentrations are Elevated in Erythrocytes of Renal Transplant Recipients when Conventional Immunosuppression is Replaced by the Inosine Monophosphate Dehydrogenase Inhibitor Mycophenolic Acid Mofetil (MMF)

Nucleosides, nucleotides & nucleic acids, 2004-10, Vol.23 (8-9), p.1407-1409

2004

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Pharmacogenetic variants in the DPYD, TYMS, CDA and MTHFR genes are clinically significant predictors of fluoropyrimidine toxicity

Review article: malignancy on thiopurine treatment with special reference to inflammatory bowel disease

Novel pharmacogenetic markers for treatment outcome in azathioprine‐treated inflammatory bowel disease

Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease

Methotrexate polyglutamates as a marker of patient compliance and clinical response in psoriasis: a single-centre prospective study

Mechanism of allopurinol induced TPMT inhibition

Genotyping before azathioprine administration in dermatology

unusual genetic variant in the MOCS1 gene leads to complete missplicing of an alternatively spliced exon in a patient with molybdenum cofactor deficiency

The effect of pre‐operative anxiety on induction of anaesthesia with propofol

Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations

A practical guide to the use of thiopurines in oral medicine

Do ITPA and TPMT genotypes predict the development of side effects to AZA?

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency

Mutation in the ITPA Gene Predicts Intolerance to Azathioprine

Deoxyuridine accumulation in urine in thymidine phosphorylase deficiency (MNGIE)

HPLC/Tandem Ion Trap Mass Detector Methods for Determination of Inosine Monophosphate Dehydrogenase (IMPDH) and Thiopurine Methyltransferase (TPMT)

Does genetic variability in aldehyde oxidase and molybdenum cofactor sulfurase predict nonresponse to allopurinol?

A biochemical mechanism for the role of allopurinol in TMPT inhibition

Pitfalls in the determination of mutant alleles of the thiopurine methyltransferase gene

Allele Frequency of Inosine Triphosphate Pyrophosphatase Gene Polymorphisms in a Japanese Population

Genetic Determinants of the Pre- and Post-Azathioprine Therapy Thiopurine Methyltransferase Activity Phenotype

Familial juvenile hyperuricaemic nephropathy

Adenylosuccinate Lyase Deficiency-First British Case

An Unusual Pyridine Nucleotide Accumulating in Erythrocytes: Its Identity, and Positive Correlation with Degree of Renal Failure

GTP Concentrations are Elevated in Erythrocytes of Renal Transplant Recipients when Conventional Immunosuppression is Replaced by the Inosine Monophosphate Dehydrogenase Inhibitor Mycophenolic Acid Mofetil (MMF)

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