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Biological characteristics of the Trypanosoma cruzi Arequipa strain make it a good model for Chagas disease drug discovery

Acta tropica, 2022-12, Vol.236, p.106679-106679, Article 106679

2022

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What are the translational challenges associated with Chagas disease drug discovery?

Expert opinion on drug discovery, 2024-11, Vol.19 (11), p.1-1296

2024

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An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment

ACS infectious diseases, 2022-06, Vol.8 (6), p.1107-1115

2022

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In Vivo Biological Evaluation of a Synthetic Royleanone Derivative as a Promising Fast-Acting Trypanocidal Agent by Inducing Mitochondrial-Dependent Necrosis

Journal of natural products (Washington, D.C.), 2020-12, Vol.83 (12), p.3571-3583

2020

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Avian Plasmodium in invasive and native mosquitoes from southern Spain

Parasites & vectors, 2024-01, Vol.17 (1), p.40-40, Article 40

2024

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First-Row Transition 7-Oxo-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidine Metal Complexes: Antiparasitic Activity and Release Studies

Pharmaceuticals (Basel, Switzerland), 2023-09, Vol.16 (10), p.1380

2023

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Assessing the effectiveness of AS-48 in experimental mice models of Chagas' disease

Journal of antimicrobial chemotherapy, 2020-06, Vol.75 (6), p.1537-1545

2020

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Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation

Bioorganic & medicinal chemistry, 2019-09, Vol.27 (17), p.3902-3917

2019

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Repositioning of leishmanicidal [1,2,3]Triazolo[1,5-a]pyridinium salts for Chagas disease treatment: Trypanosoma cruzi cell death involving mitochondrial membrane depolarisation and Fe-SOD inhibition

Parasitology research (1987), 2020-09, Vol.119 (9), p.2943-2954

2020

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The Bioactivity of Xylene, Pyridine, and Pyrazole Aza Macrocycles against Three Representative Leishmania Species

Pharmaceutics, 2023-03, Vol.15 (3), p.992

2023

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5-Nitroindazole derivatives as potential therapeutic alternatives against Acanthamoeba castellanii

Acta tropica, 2022-08, Vol.232, p.106538-106538, Article 106538

2022

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In vitro anti-Acanthamoeba activity of flavonoid glycosides isolated from Delphinium gracile, D. staphisagria, Consolida oliveriana and Aconitum napellus

Parasitology, 2021-09, Vol.148 (11), p.1392-1400

2021

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Correction: Avian Plasmodium in invasive and native mosquitoes from southern Spain

Parasites & vectors, 2024-03, Vol.17 (1), p.133-133, Article 133

2024

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Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies

ACS infectious diseases, 2021-06, Vol.7 (6), p.1727-1738

2021

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Phthalazine Derivatives Containing Imidazole Rings Behave as Fe-SOD Inhibitors and Show Remarkable Anti-T. cruzi Activity in Immunodeficient-Mouse Mode of Infection

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.9900-9913

2012

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Synthesis and biological evaluation of new long-chain squaramides as anti-chagasic agents in the BALB/c mouse model

Bioorganic & medicinal chemistry, 2019-03, Vol.27 (5), p.865-879

2019

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Library of Seleno-Compounds as Novel Agents against Leishmania Species

Antimicrobial agents and chemotherapy, 2017-06, Vol.61 (6)

2017

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Insights into Chagas treatment based on the potential of bacteriocin AS-48

International journal for parasitology -- drugs and drug resistance, 2019-08, Vol.10, p.1-8

2019

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A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives

European journal of medicinal chemistry, 2019-02, Vol.163, p.569-582

2019

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Triazolopyrimidine compounds containing first-row transition metals and their activity against the neglected infectious Chagas disease and leishmaniasis

European journal of medicinal chemistry, 2014-10, Vol.85, p.526-534

2014

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New perspectives on the synthesis and antichagasic activity of 3-alkoxy-1-alkyl-5-nitroindazoles

European journal of medicinal chemistry, 2014-03, Vol.74, p.124-134

2014

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In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species

Journal of antimicrobial chemotherapy, 2012-02, Vol.67 (2), p.387-397

2012

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In Vitro and in Vivo Trypanosomicidal Activity of Pyrazole-Containing Macrocyclic and Macrobicyclic Polyamines: Their Action on Acute and Chronic Phases of Chagas Disease

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4231-4243

2012

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Excreted Leishmania peruviana and Leishmania amazonensis iron-superoxide dismutase purification: specific antibody detection in Colombian patients with cutaneous leishmaniasis

Free radical biology & medicine, 2014-04, Vol.69, p.26-34

2014

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New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases

European journal of medicinal chemistry, 2019-02, Vol.164, p.27-46

2019

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Biological characteristics of the Trypanosoma cruzi Arequipa strain make it a good model for Chagas disease drug discovery

What are the translational challenges associated with Chagas disease drug discovery?

An Updated View of the Trypanosoma cruzi Life Cycle: Intervention Points for an Effective Treatment

In Vivo Biological Evaluation of a Synthetic Royleanone Derivative as a Promising Fast-Acting Trypanocidal Agent by Inducing Mitochondrial-Dependent Necrosis

Avian Plasmodium in invasive and native mosquitoes from southern Spain

First-Row Transition 7-Oxo-5-phenyl-1,2,4-triazolo[1,5-a]pyrimidine Metal Complexes: Antiparasitic Activity and Release Studies

Assessing the effectiveness of AS-48 in experimental mice models of Chagas' disease

Rational modification of Mannich base-type derivatives as novel antichagasic compounds: Synthesis, in vitro and in vivo evaluation

Repositioning of leishmanicidal [1,2,3]Triazolo[1,5-a]pyridinium salts for Chagas disease treatment: Trypanosoma cruzi cell death involving mitochondrial membrane depolarisation and Fe-SOD inhibition

The Bioactivity of Xylene, Pyridine, and Pyrazole Aza Macrocycles against Three Representative Leishmania Species

5-Nitroindazole derivatives as potential therapeutic alternatives against Acanthamoeba castellanii

In vitro anti-Acanthamoeba activity of flavonoid glycosides isolated from Delphinium gracile, D. staphisagria, Consolida oliveriana and Aconitum napellus

Correction: Avian Plasmodium in invasive and native mosquitoes from southern Spain

Selenium Derivatives as Promising Therapy for Chagas Disease: In Vitro and In Vivo Studies

Phthalazine Derivatives Containing Imidazole Rings Behave as Fe-SOD Inhibitors and Show Remarkable Anti-T. cruzi Activity in Immunodeficient-Mouse Mode of Infection

Synthesis and biological evaluation of new long-chain squaramides as anti-chagasic agents in the BALB/c mouse model

Library of Seleno-Compounds as Novel Agents against Leishmania Species

Insights into Chagas treatment based on the potential of bacteriocin AS-48

A step towards development of promising trypanocidal agents: Synthesis, characterization and in vitro biological evaluation of ferrocenyl Mannich base-type derivatives

Triazolopyrimidine compounds containing first-row transition metals and their activity against the neglected infectious Chagas disease and leishmaniasis

New perspectives on the synthesis and antichagasic activity of 3-alkoxy-1-alkyl-5-nitroindazoles

In vitro leishmanicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against Leishmania infantum and Leishmania braziliensis species

In Vitro and in Vivo Trypanosomicidal Activity of Pyrazole-Containing Macrocyclic and Macrobicyclic Polyamines: Their Action on Acute and Chronic Phases of Chagas Disease

Excreted Leishmania peruviana and Leishmania amazonensis iron-superoxide dismutase purification: specific antibody detection in Colombian patients with cutaneous leishmaniasis

New polyamine drugs as more effective antichagas agents than benznidazole in both the acute and chronic phases

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