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Mechanistic Insights on the Cycloisomerization of Polyunsaturated Precursors Catalyzed by Platinum and Gold Complexes

Accounts of chemical research, 2009-08, Vol.42 (8), p.1026-1036

2009

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Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

Journal of medicinal chemistry, 2011-12, Vol.54 (24), p.8251-8270

2011

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α-Phenyl- N-tert -Butylnitrone and Analogous α-Aryl- N -alkylnitrones as Neuroprotective Antioxidant Agents for Stroke

Antioxidants, 2024-04, Vol.13 (4), p.440

Marco-Contelles, José

2024

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Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

Angewandte Chemie International Edition, 2017-10, Vol.56 (41), p.12765-12769

International ed. in English, 2017

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Synthesis and Antioxidant Activity of N-Benzyl-2-[4-(aryl)-1H-1,2,3-triazol-1-yl]ethan-1-imine Oxides

International journal of molecular sciences, 2024-06, Vol.25 (11), p.5908

2024

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Mechanisms of the Transition Metal-Mediated Hydroarylation of Alkynes and Allenes

Organometallics, 2006-09, Vol.25 (19), p.4542-4553

2006

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Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

Medicinal research reviews, 2013-01, Vol.33 (1), p.139-189

2013

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Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

Molecules (Basel, Switzerland), 2023-01, Vol.28 (1), p.71

2023

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N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

Molecules (Basel, Switzerland), 2022-11, Vol.27 (21), p.7437

2022

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Neuroprotective and antioxidant properties of new quinolylnitrones in in vitro and in vivo cerebral ischemia models

Scientific reports, 2023-02, Vol.13 (1), p.2865-2865, Article 2865

2023

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Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties

Molecules (Basel, Switzerland), 2022-11, Vol.27 (22), p.7878

2022

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Efficacy of Acetylcholinesterase Inhibitors on Cognitive Function in Alzheimer’s Disease. Review of Reviews

Biomedicines, 2021-11, Vol.9 (11), p.1689

2021

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Recent Advances on Nitrones Design for Stroke Treatment: Miniperspective

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13413-13427

Marco-Contelles, José

2020

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Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7652

2020

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Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment

International journal of molecular sciences, 2023-06, Vol.24 (11), p.9742

2023

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Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

Journal of enzyme inhibition and medicinal chemistry, 2022-12, Vol.37 (1), p.2605-2620

2022

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Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7449

2022

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Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (5), p.588

2024

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Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal Injury

Pharmaceuticals (Basel, Switzerland), 2022-11, Vol.15 (11), p.1363

2022

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Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy

Molecules (Basel, Switzerland), 2020-07, Vol.25 (14), p.3190

2020

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The Proof-of-Concept of MBA121, a Tacrine-Ferulic Acid Hybrid, for Alzheimer's Disease Therapy

International journal of molecular sciences, 2023-07, Vol.24 (15), p.12254

2023

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Homo-Tris-Nitrones Derived from α-Phenyl- N-tert -butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties

International journal of molecular sciences, 2020-10, Vol.21 (21), p.7949

2020

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Naturally Occurring Cyclohexane Epoxides: Sources, Biological Activities, and Synthesis

Chemical reviews, 2004-06, Vol.104 (6), p.2857-2900

2004

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Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

Molecules (Basel, Switzerland), 2020-03, Vol.25 (6), p.1329

2020

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Highlights of ASS234: a novel and promising therapeutic agent for Alzheimer's disease therapy

Neural regeneration research, 2020-01, Vol.15 (1), p.30-35

2020

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Mechanistic Insights on the Cycloisomerization of Polyunsaturated Precursors Catalyzed by Platinum and Gold Complexes

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

α-Phenyl- N-tert -Butylnitrone and Analogous α-Aryl- N -alkylnitrones as Neuroprotective Antioxidant Agents for Stroke

Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3R Antagonism for Neurodegenerative Diseases

Synthesis and Antioxidant Activity of N-Benzyl-2-[4-(aryl)-1H-1,2,3-triazol-1-yl]ethan-1-imine Oxides

Mechanisms of the Transition Metal-Mediated Hydroarylation of Alkynes and Allenes

Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease

Biginelli Reaction Synthesis of Novel Multitarget-Directed Ligands with Ca2+ Channel Blocking Ability, Cholinesterase Inhibition, Antioxidant Capacity, and Nrf2 Activation

N-Hydroxy-N-Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases

Neuroprotective and antioxidant properties of new quinolylnitrones in in vitro and in vivo cerebral ischemia models

Benzochromenopyrimidines: Synthesis, Antiproliferative Activity against Colorectal Cancer and Physicochemical Properties

Efficacy of Acetylcholinesterase Inhibitors on Cognitive Function in Alzheimer’s Disease. Review of Reviews

Recent Advances on Nitrones Design for Stroke Treatment: Miniperspective

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives

Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment

Privileged multi-target directed propargyl-tacrines combining cholinesterase and monoamine oxidase inhibition activities

Postischemic Neuroprotection of Aminoethoxydiphenyl Borate Associates Shortening of Peri-Infarct Depolarizations

Cholesterol Oxime Olesoxime Assessed as a Potential Ligand of Human Cholinesterases

Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal Injury

Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy

The Proof-of-Concept of MBA121, a Tacrine-Ferulic Acid Hybrid, for Alzheimer's Disease Therapy

Homo-Tris-Nitrones Derived from α-Phenyl- N-tert -butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties

Naturally Occurring Cyclohexane Epoxides: Sources, Biological Activities, and Synthesis

Design, Synthesis and Biological Evaluation of New Antioxidant and Neuroprotective Multitarget Directed Ligands Able to Block Calcium Channels

Highlights of ASS234: a novel and promising therapeutic agent for Alzheimer's disease therapy

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