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In silico trials: Verification, validation and uncertainty quantification of predictive models used in the regulatory evaluation of biomedical products

Methods (San Diego, Calif.), 2021-01, Vol.185, p.120-127

2021

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The Virtual Physiological Human: Ten Years After

Annual review of biomedical engineering, 2016-07, Vol.18 (1), p.103-123

2016

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The effect of boundary and loading conditions on patient classification using finite element predicted risk of fracture

Clinical biomechanics (Bristol), 2019-08, Vol.68, p.137-143

2019

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Subject-specific finite element models implementing a maximum principal strain criterion are able to estimate failure risk and fracture location on human femurs tested in vitro

Journal of biomechanics, 2008-01, Vol.41 (2), p.356-367

2008

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In silico trial to test COVID-19 candidate vaccines: a case study with UISS platform

BMC bioinformatics, 2020-12, Vol.21 (Suppl 17), p.527-527, Article 527

2020

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Three-dimensional local measurements of bone strain and displacement: comparison of three digital volume correlation approaches

Journal of biomechanical engineering, 2015-07, Vol.137 (7)

2015

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Effect of Suboptimal Neuromuscular Control on the Risk of Massive Wear in Total Knee Replacement

Annals of biomedical engineering, 2021-12, Vol.49 (12), p.3349-3355

2021

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Are subject-specific musculoskeletal models robust to the uncertainties in parameter identification?

PloS one, 2014-11, Vol.9 (11), p.e112625

2014

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Experimental validation of a subject-specific finite element model of lumbar spine segment using digital image correlation

PloS one, 2022-09, Vol.17 (9), p.e0272529-e0272529

2022

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A systematic approach to the scale separation problem in the development of multiscale models

PloS one, 2021-05, Vol.16 (5), p.e0251297-e0251297

2021

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Micro Finite Element models of the vertebral body: Validation of local displacement predictions

PloS one, 2017-07, Vol.12 (7), p.e0180151-e0180151

2017

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Myobolica: A Stochastic Approach to Estimate Physiological Muscle Control Variability

IEEE transactions on neural systems and rehabilitation engineering, 2024, Vol.32, p.3270-3277

2024

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Phantomless calibration of CT scans for hip fracture risk prediction in silico: Comparison with phantom-based calibration

PloS one, 2024-06, Vol.19 (6), p.e0305474

2024

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Toward a Regulatory Qualification of Real-World Mobility Performance Biomarkers in Parkinson's Patients Using Digital Mobility Outcomes

Sensors (Basel, Switzerland), 2020-10, Vol.20 (20), p.5920

2020

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Image-Based Musculoskeletal Models to Accurately Reproduce a Maximum Voluntary Isometric Contraction Test In Silico

Applied sciences, 2024-10, Vol.14 (19), p.8678

2024

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Mathematical relationships between bone density and mechanical properties: A literature review

Clinical biomechanics (Bristol), 2008-02, Vol.23 (2), p.135-146

2008

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Finite Element Models to Predict the Risk of Aseptic Loosening in Cementless Femoral Stems: A Literature Review

Applied sciences, 2024-04, Vol.14 (8), p.3200

2024

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The human proximal femur behaves linearly elastic up to failure under physiological loading conditions

Journal of biomechanics, 2011-08, Vol.44 (12), p.2259-2266

2011

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The material mapping strategy influences the accuracy of CT-based finite element models of bones: An evaluation against experimental measurements

Medical engineering & physics, 2007-11, Vol.29 (9), p.973-979

2007

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A new method to monitor bone geometry changes at different spatial scales in the longitudinal in vivo μCT studies of mice bones

PloS one, 2019-07, Vol.14 (7), p.e0219404-e0219404

2019

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Personalised 3D Assessment of Trochanteric Soft Tissues Improves HIP Fracture Classification Accuracy

Annals of biomedical engineering, 2022-03, Vol.50 (3), p.303-313

2022

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Generation of digital patients for the simulation of tuberculosis with UISS-TB

BMC bioinformatics, 2020-12, Vol.21 (Suppl 17), p.449-449, Article 449

2020

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An accurate estimation of bone density improves the accuracy of subject-specific finite element models

Journal of biomechanics, 2008, Vol.41 (11), p.2483-2491

2008

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Predicting the artificial immunity induced by RUTI® vaccine against tuberculosis using universal immune system simulator (UISS)

BMC bioinformatics, 2019-12, Vol.20 (Suppl 6), p.504-10, Article 504

2019

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Development and validation of a semi-automated and unsupervised method for femur segmentation from CT

Scientific reports, 2024-03, Vol.14 (1), p.7403-7403, Article 7403

2024

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In silico trials: Verification, validation and uncertainty quantification of predictive models used in the regulatory evaluation of biomedical products

The Virtual Physiological Human: Ten Years After

The effect of boundary and loading conditions on patient classification using finite element predicted risk of fracture

Subject-specific finite element models implementing a maximum principal strain criterion are able to estimate failure risk and fracture location on human femurs tested in vitro

In silico trial to test COVID-19 candidate vaccines: a case study with UISS platform

Three-dimensional local measurements of bone strain and displacement: comparison of three digital volume correlation approaches

Effect of Suboptimal Neuromuscular Control on the Risk of Massive Wear in Total Knee Replacement

Are subject-specific musculoskeletal models robust to the uncertainties in parameter identification?

Experimental validation of a subject-specific finite element model of lumbar spine segment using digital image correlation

A systematic approach to the scale separation problem in the development of multiscale models

Micro Finite Element models of the vertebral body: Validation of local displacement predictions

Myobolica: A Stochastic Approach to Estimate Physiological Muscle Control Variability

Phantomless calibration of CT scans for hip fracture risk prediction in silico: Comparison with phantom-based calibration

Toward a Regulatory Qualification of Real-World Mobility Performance Biomarkers in Parkinson's Patients Using Digital Mobility Outcomes

Image-Based Musculoskeletal Models to Accurately Reproduce a Maximum Voluntary Isometric Contraction Test In Silico

Mathematical relationships between bone density and mechanical properties: A literature review

Finite Element Models to Predict the Risk of Aseptic Loosening in Cementless Femoral Stems: A Literature Review

The human proximal femur behaves linearly elastic up to failure under physiological loading conditions

The material mapping strategy influences the accuracy of CT-based finite element models of bones: An evaluation against experimental measurements

A new method to monitor bone geometry changes at different spatial scales in the longitudinal in vivo μCT studies of mice bones

Personalised 3D Assessment of Trochanteric Soft Tissues Improves HIP Fracture Classification Accuracy

Generation of digital patients for the simulation of tuberculosis with UISS-TB

An accurate estimation of bone density improves the accuracy of subject-specific finite element models

Predicting the artificial immunity induced by RUTI® vaccine against tuberculosis using universal immune system simulator (UISS)

Development and validation of a semi-automated and unsupervised method for femur segmentation from CT

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