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PFunkel: efficient, expansive, user-defined mutagenesis

PloS one, 2012-12, Vol.7 (12), p.e52031

2012

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Shifting Fitness and Epistatic Landscapes Reflect Trade-offs along an Evolutionary Pathway

Journal of molecular biology, 2016-07, Vol.428 (13), p.2730-2743

2016

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A bacterial dual positive and negative selection system for dCas9 activity

PloS one, 2022-06, Vol.17 (6), p.e0269270-e0269270

2022

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Environmental changes bridge evolutionary valleys

Science advances, 2016-01, Vol.2 (1), p.e1500921-e1500921

2016

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Directed evolution of improved zinc finger methyltransferases

PloS one, 2014-05, Vol.9 (5), p.e96931-e96931

2014

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Targeted DNA methylation in human cells using engineered dCas9-methyltransferases

Scientific reports, 2017-07, Vol.7 (1), p.6732-14, Article 6732

2017

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Design of protein switches based on an ensemble model of allostery

Nature communications, 2015-04, Vol.6 (1), p.6968-6968, Article 6968

2015

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Multifunctional "Clickates" as Versatile Extended Heteroaromatic Building Blocks: Efficient Synthesis via Click Chemistry, Conformational Preferences, and Metal Coordination

Chemistry : a European journal, 2007-01, Vol.13 (35), p.9834-9840

2007

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Dual column approach for the purification of zinc finger proteins by immobilized metal affinity chromatography

Process biochemistry (1991), 2018-10, Vol.73, p.204-210

2018

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Directed Evolution of Protein Switches and Their Application to the Creation of Ligand-Binding Proteins

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (32), p.11224-11229

2005

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Molecular Imprinting of Maltose Binding Protein: Tuning Protein Recognition at the Molecular Level

Macromolecules, 2011-05, Vol.44 (10), p.3966-3972

2011

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A Positive Selection for Nucleoside Kinases in E. coli

PloS one, 2016-09, Vol.11 (9), p.e0162921

2016

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Circular permutation in the Ω-loop of TEM-1 β-lactamase results in improved activity and altered substrate specificity

PloS one, 2012-04, Vol.7 (4), p.e35998

2012

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Fitness and Functional Landscapes of the E. coli RNase III Gene rnc

Molecular biology and evolution, 2023-03, Vol.40 (3)

2023

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Protein engineering strategies for improving the selective methylation of target CpG sites by a dCas9-directed cytosine methyltransferase in bacteria

PloS one, 2018-12, Vol.13 (12), p.e0209408

2018

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externally tunable bacterial band-pass filter

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (25), p.10135-10140

2009

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Targeted DNA methylation using an artificially bisected M.HhaI fused to zinc fingers

PloS one, 2012-09, Vol.7 (9), p.e44852-e44852

2012

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Designing switchable enzymes

Current opinion in structural biology, 2009-08, Vol.19 (4), p.442-448

Ostermeier, Marc

2009

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protein therapeutic modality founded on molecular regulation

Proceedings of the National Academy of Sciences - PNAS, 2011-09, Vol.108 (39), p.16206-16211

2011

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Engineered protein switches for exogenous control of gene expression

Biochemical Society transactions, 2020-10, Vol.48 (5), p.2205-2212

2020

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Rational Design of a Fusion Protein to Exhibit Disulfide-Mediated Logic Gate Behavior

ACS synthetic biology, 2015-04, Vol.4 (4), p.400-406

2015

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Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy

PloS one, 2014-11, Vol.9 (11), p.e114032

2014

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The genetic code constrains yet facilitates Darwinian evolution

Nucleic acids research, 2013-08, Vol.41 (15), p.7420-7428

2013

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A comprehensive, high-resolution map of a gene's fitness landscape

Molecular biology and evolution, 2014-06, Vol.31 (6), p.1581-1592

2014

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PFunkel: efficient, expansive, user-defined mutagenesis

Shifting Fitness and Epistatic Landscapes Reflect Trade-offs along an Evolutionary Pathway

A bacterial dual positive and negative selection system for dCas9 activity

Environmental changes bridge evolutionary valleys

Directed evolution of improved zinc finger methyltransferases

Targeted DNA methylation in human cells using engineered dCas9-methyltransferases

Design of protein switches based on an ensemble model of allostery

Multifunctional "Clickates" as Versatile Extended Heteroaromatic Building Blocks: Efficient Synthesis via Click Chemistry, Conformational Preferences, and Metal Coordination

Dual column approach for the purification of zinc finger proteins by immobilized metal affinity chromatography

Directed Evolution of Protein Switches and Their Application to the Creation of Ligand-Binding Proteins

Molecular Imprinting of Maltose Binding Protein: Tuning Protein Recognition at the Molecular Level

A Positive Selection for Nucleoside Kinases in E. coli

Circular permutation in the Ω-loop of TEM-1 β-lactamase results in improved activity and altered substrate specificity

Fitness and Functional Landscapes of the E. coli RNase III Gene rnc

Comprehensive Analysis of Aspergillus nidulans PKA Phosphorylome Identifies a Novel Mode of CreA Regulation

Protein engineering strategies for improving the selective methylation of target CpG sites by a dCas9-directed cytosine methyltransferase in bacteria

externally tunable bacterial band-pass filter

Targeted DNA methylation using an artificially bisected M.HhaI fused to zinc fingers

Designing switchable enzymes

protein therapeutic modality founded on molecular regulation

Engineered protein switches for exogenous control of gene expression

Rational Design of a Fusion Protein to Exhibit Disulfide-Mediated Logic Gate Behavior

Advancements in the development of HIF-1α-activated protein switches for use in enzyme prodrug therapy

The genetic code constrains yet facilitates Darwinian evolution

A comprehensive, high-resolution map of a gene's fitness landscape

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