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Robust, universal biomarker assay to detect senescent cells in biological specimens

Aging cell, 2017-02, Vol.16 (1), p.192-197

2017

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Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues

Molecules (Basel, Switzerland), 2020-10, Vol.25 (19), p.4531

2020

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Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

Molecules (Basel, Switzerland), 2021-12, Vol.27 (1), p.247

2021

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Fused xanthone derivatives as antiproliferative agents

Anti-cancer agents in medicinal chemistry, 2009-01, Vol.9 (1), p.77-98

2009

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Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives

Molecules (Basel, Switzerland), 2020-10, Vol.25 (19), p.4584

2020

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Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors

Molecules (Basel, Switzerland), 2020-08, Vol.25 (16), p.3739

2020

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Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer

Pharmaceutics, 2023-02, Vol.15 (3), p.787

2023

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The pyrazolo[4,3-c]pyrazole core as a novel and versatile scaffold for developing dual DYRK1A-CLK1 inhibitors targeting key processes of Alzheimer's disease pathology

European journal of medicinal chemistry reports, 2024-12, Vol.12, p.100193, Article 100193

2024

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Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines

Chemical and Pharmaceutical Bulletin, 2017/01/01, Vol.65(1), pp.66-81

2017

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Synthesis of New Nebularine Analogues and Their Inhibitory Activity against Adenosine Deaminase

Chemical and Pharmaceutical Bulletin, 2015/02/01, Vol.63(2), pp.134-142

2015

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Design and Synthesis of New Substituted Pyrazolopyridines with Potent Antiproliferative Activity

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2020-01, Vol.16 (2), p.176-191

2020

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Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities

Arabian journal of chemistry, 2020-11, Vol.13 (11), p.7953-7969

2020

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One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16

STAR protocols, 2024-03, Vol.5 (1), p.102929-102929, Article 102929

2024

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Synthesis of New Nebularine Analogues and Their Inhibitory Activity against Adenosine Deaminase

Chemical and Pharmaceutical Bulletin, 2015-02, Vol.63 (2), p.134-142

2015

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Synthesis and Antiviral Activity Evaluation of some Novel Acyclic C-Nucleosides

Chemical and Pharmaceutical Bulletin, 2008/06/01, Vol.56(6), pp.775-780

2008

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Synthesis and free radical scavenging activity of some new spiropyranocoumarins

Bioorganic & medicinal chemistry, 2008-11, Vol.18 (21), p.5781-5784

2008

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Discovery of New Aminosubstituted Pyrrolopyrimidines with Antiproliferative Activity Against Breast Cancer Cells and Investigation of their Effect Towards the PI3Kα Enzyme

Anti-cancer agents in medicinal chemistry, 2017-01, Vol.17 (7), p.990

2017

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Synthesis and Antiproliferative Activity of New pyrazolo[3,4-c]pyridines

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2017-06, Vol.13 (4), p.365-374

2017

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Design and synthesis of new C-nucleosides as potential adenosine deaminase inhibitors

Tetrahedron, 2010-12, Vol.66 (50), p.9620-9628

2010

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The Synthesis of the New C-Nucleoside 6-Deazaformycin B

Synlett, 2008-01, Vol.2008 (2), p.181-184

2008

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Design, synthesis and cytotoxic activity evaluation of new aminosubstituted benzofurans

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2014-01, Vol.10 (6), p.619-627

2014

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Design, Synthesis, and Evaluation of the Antiproliferative Activity of a Series of Novel Fused Xanthenone Aminoderivatives in Human Breast Cancer Cells

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1716-1719

2007

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Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure−Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.13305-13327

2022

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Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor

Journal of medicinal chemistry, 2024-08, Vol.67 (15), p.13117-13146

2024

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New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships

European journal of medicinal chemistry, 2021-06, Vol.218, p.113387-113387, Article 113387

2021

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Robust, universal biomarker assay to detect senescent cells in biological specimens

Synthesis of New Imidazopyridine Nucleoside Derivatives Designed as Maribavir Analogues

Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation

Fused xanthone derivatives as antiproliferative agents

Synthesis, Biological Evaluation and Stability Studies of Some Novel Aza-Acridine Aminoderivatives

Screening of Heteroaromatic Scaffolds against Cystathionine Beta-Synthase Enables Identification of Substituted Pyrazolo[3,4-c]Pyridines as Potent and Selective Orthosteric Inhibitors

Discovery of New 1,4,6-Trisubstituted-1H-pyrazolo[3,4-b]pyridines with Anti-Tumor Efficacy in Mouse Model of Breast Cancer

The pyrazolo[4,3-c]pyrazole core as a novel and versatile scaffold for developing dual DYRK1A-CLK1 inhibitors targeting key processes of Alzheimer's disease pathology

Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines

Synthesis of New Nebularine Analogues and Their Inhibitory Activity against Adenosine Deaminase

Design and Synthesis of New Substituted Pyrazolopyridines with Potent Antiproliferative Activity

Synthesis of novel xanthone and acridone carboxamides with potent antiproliferative activities

One-step rapid tracking and isolation of senescent cells in cellular systems, tissues, or animal models via GLF16

Synthesis of New Nebularine Analogues and Their Inhibitory Activity against Adenosine Deaminase

Synthesis and Antiviral Activity Evaluation of some Novel Acyclic C-Nucleosides

Synthesis and free radical scavenging activity of some new spiropyranocoumarins

Discovery of New Aminosubstituted Pyrrolopyrimidines with Antiproliferative Activity Against Breast Cancer Cells and Investigation of their Effect Towards the PI3Kα Enzyme

Synthesis and Antiproliferative Activity of New pyrazolo[3,4-c]pyridines

Design and synthesis of new C-nucleosides as potential adenosine deaminase inhibitors

The Synthesis of the New C-Nucleoside 6-Deazaformycin B

Design, synthesis and cytotoxic activity evaluation of new aminosubstituted benzofurans

Design, Synthesis, and Evaluation of the Antiproliferative Activity of a Series of Novel Fused Xanthenone Aminoderivatives in Human Breast Cancer Cells

Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure−Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations

Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor

New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships

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