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In vitro and in vivo SAR of pyrido[3,4- d]pyramid-4-ylamine based mGluR1 antagonists

Bioorganic & medicinal chemistry letters, 2009-04, Vol.19 (8), p.2190-2194

2009

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SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4471-4475

2009

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SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4471

2009

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Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1284-1287

2008

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Structure–activity relationships of novel non-competitive mGluR1 antagonists: A potential treatment for chronic pain

Bioorganic & medicinal chemistry letters, 2007-01, Vol.17 (2), p.486-490

2007

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Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry letters, 2008-02, Vol.18 (4), p.1284-1287

2008

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Dearomatizing Disrotatory Electrocyclic Ring Closure of Lithiated N-Benzoyloxazolidines

Angewandte Chemie (International ed.), 2002-03, Vol.41 (6), p.1049-1051

2002

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SAR of a series of inhaled A sub(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (15), p.4471-4475

2009

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Inhaled adenosine A sub(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry, 2008-02, Vol.18 (4), p.1284-1287

2008

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Inhaled adenosine A 2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (4), p.1284-1287

2008

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Dearomatizing Disrotatory Electrocyclic Ring Closure of LithiatedN-Benzoyloxazolidines

Angewandte Chemie, 2002-03, Vol.114 (6), p.1091-1093

2002

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Dearomatizing Disrotatory Electrocyclic Ring Closure of Lithiated N-Benzoyloxazolidines

Angewandte Chemie, 2002-03, Vol.114 (6), p.1091-1093

2002

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3-Hydroxymuscarines from L-Rhamnose

Tetrahedron, 1993-04, Vol.49 (16), p.3343-3358

1993

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Acid-catalysed transformation of α-trifluoromethanesulfonates of γ- and δ-lactones into 2,5-disubstituted homochiral tetrahydrofurans

Journal of the Chemical Society. Chemical communications, 1993 (13), p.1065-1067

1993

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(+)-muscarine from L-rhamnose

Journal of the Chemical Society. Chemical communications, 1991 (21), p.1563-1564

1991

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A radical route to 2( [formula omitted])-4-exomethylene proline

Tetrahedron, 1992, Vol.48 (31), p.6529-6536

1992

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The ring contraction of δ-lactones with leaving group α-substituents : a strategy for the synthesis of 2,5-disubstituted highly functionalised homochiral tetrahydrofurans

Journal of the Chemical Society. Chemical communications, 1992 (21), p.1605-1607

1992

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3R-Hydroxymuscarine from L-rhamnose without protection

Tetrahedron letters, 1992-07, Vol.33 (31), p.4503-4506

1992

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Synthesis of highly functionalised homochiral compounds

Mantell, Simon J

1993

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ChemInform Abstract: Dearomatizing Disrotatory Electrocyclic Ring Closure of Lithiated N-Benzoyloxazolidines

ChemInform, 2002-08, Vol.33 (31), p.no-no

2002

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Major Clinical Outcomes in Antiretroviral Therapy (ART)–Naive Participants and in Those Not Receiving ART at Baseline in the SMART Study

The Journal of infectious diseases, 2008-04, Vol.197 (8), p.1133-1144

2008

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Inferior Clinical Outcome of the CD4+ Cell Count–Guided Antiretroviral Treatment Interruption Strategy in the SMART Study: Role of CD4+ Cell Counts and HIV RNA Levels during Follow-up

The Journal of infectious diseases, 2008-04, Vol.197 (8), p.1145-1155

2008

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Activation and Coagulation Biomarkers Are Independent Predictors of the Development of Opportunistic Disease in Patients with HIV Infection

The Journal of infectious diseases, 2009-09, Vol.200 (6), p.973-983

2009

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Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trial

Annals of internal medicine, 2008-09, Vol.149 (5), p.289

2008

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Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study

PloS one, 2015-10, Vol.10 (10), p.e0139981-e0139981

2015

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In vitro and in vivo SAR of pyrido[3,4- d]pyramid-4-ylamine based mGluR1 antagonists

SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Structure–activity relationships of novel non-competitive mGluR1 antagonists: A potential treatment for chronic pain

Inhaled adenosine A(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Dearomatizing Disrotatory Electrocyclic Ring Closure of Lithiated N-Benzoyloxazolidines

SAR of a series of inhaled A sub(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Inhaled adenosine A sub(2A) receptor agonists for the treatment of chronic obstructive pulmonary disease

Inhaled adenosine A 2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Dearomatizing Disrotatory Electrocyclic Ring Closure of LithiatedN-Benzoyloxazolidines

Dearomatizing Disrotatory Electrocyclic Ring Closure of Lithiated N-Benzoyloxazolidines

3-Hydroxymuscarines from L-Rhamnose

Acid-catalysed transformation of α-trifluoromethanesulfonates of γ- and δ-lactones into 2,5-disubstituted homochiral tetrahydrofurans

(+)-muscarine from L-rhamnose

A radical route to 2( [formula omitted])-4-exomethylene proline

The ring contraction of δ-lactones with leaving group α-substituents : a strategy for the synthesis of 2,5-disubstituted highly functionalised homochiral tetrahydrofurans

3R-Hydroxymuscarine from L-rhamnose without protection

Synthesis of highly functionalised homochiral compounds

ChemInform Abstract: Dearomatizing Disrotatory Electrocyclic Ring Closure of Lithiated N-Benzoyloxazolidines

Major Clinical Outcomes in Antiretroviral Therapy (ART)–Naive Participants and in Those Not Receiving ART at Baseline in the SMART Study

Inferior Clinical Outcome of the CD4+ Cell Count–Guided Antiretroviral Treatment Interruption Strategy in the SMART Study: Role of CD4+ Cell Counts and HIV RNA Levels during Follow-up

Activation and Coagulation Biomarkers Are Independent Predictors of the Development of Opportunistic Disease in Patients with HIV Infection

Risk for opportunistic disease and death after reinitiating continuous antiretroviral therapy in patients with HIV previously receiving episodic therapy: a randomized trial

Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study

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