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Telencephalon‐specific Alkbh1 conditional knockout mice display hippocampal atrophy and impaired learning

FEBS letters, 2021-06, Vol.595 (12), p.1671-1680

2021

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PDGF‐dependent β‐catenin activation is associated with abnormal pulmonary artery smooth muscle cell proliferation in pulmonary arterial hypertension

FEBS letters, 2016-01, Vol.590 (1), p.101-109

2016

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The pluripotency transcription factor OCT4 represses heme oxygenase‐1 gene expression

FEBS letters, 2021-07, Vol.595 (14), p.1949-1961

2021

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A subset of enteroendocrine cells is activated by amino acids in the Drosophila midgut

FEBS letters, 2016-02, Vol.590 (4), p.493-500

2016

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Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway

FEBS letters, 2016-02, Vol.590 (4), p.559-570

2016

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MRP 1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum

FEBS letters, 2016-02, Vol.590 (4), p.482-492

2016

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The potential role of regulator of G‐protein signaling 16 in cell motility mediated by δ EF 1 family proteins

FEBS letters, 2016-01, Vol.590 (2), p.270-278

2016

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Letter: gastritis in paediatric patients with coeliac disease

Alimentary pharmacology & therapeutics, 2016-11, Vol.44 (9), p.1003-1004

2016

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Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467

Journal of organic chemistry, 2023-11, Vol.88 (22), p.15562-15568

2023

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C/EBP homologous protein (CHOP) up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform

FEBS letters, 2003-04, Vol.541 (1), p.33-39

2003

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Influence of Weld Heat Input on the Fracture and Metallurgy of HSLA-65

Canadian metallurgical quarterly, 2009-09, Vol.48 (3), p.311-316

2009

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Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitors

Bioorganic & medicinal chemistry letters, 2018-06, Vol.28 (10), p.1804-1810

2018

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Methylpyrrole inhibitors of BET bromodomains

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (10), p.2225-2233

2017

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1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyano- pyrazi-2-yl)ureas as Potent and Selective Inhibitors of Chk1 Kinase: Synthesis, Preliminary SAR, and Biological Activities

Journal of medicinal chemistry, 2005-05, Vol.48 (9), p.3118-3121

2005

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2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ETA Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

Journal of medicinal chemistry, 1996-03, Vol.39 (5), p.1039-1048

1996

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An initiator and its flanking elements function as a core promoter driving transcription of the Hepatopoietin gene

FEBS letters, 2003-04, Vol.540 (1), p.58-64

2003

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Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases

Bioorganic & medicinal chemistry letters, 2010-10, Vol.20 (20), p.6067-6071

2010

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Discovery and Optimization of Anthranilic Acid Sulfonamides as Inhibitors of Methionine Aminopeptidase-2: A Structural Basis for the Reduction of Albumin Binding

Journal of medicinal chemistry, 2006-06, Vol.49 (13), p.3832-3849

2006

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Nonpeptide Renin Inhibitors with Good Intraduodenal Bioavailability and Efficacy in Dog

Journal of medicinal chemistry, 1994-09, Vol.37 (19), p.2991-3007

1994

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Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (10), p.2817-2822

2007

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Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ET A receptor selectivity

Bioorganic & medicinal chemistry, 1999-06, Vol.7 (6), p.991-1002

1999

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C-Terminal modifications of nonpeptide renin inhibitors: improved oral bioavailability via modification of physicochemical properties

Journal of medicinal chemistry, 1992-05, Vol.35 (10), p.1735-1746

1992

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Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ETA receptor selectivity

Bioorganic & medicinal chemistry, 1999-06, Vol.7 (6), p.991-1002

1999

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Telencephalon‐specific Alkbh1 conditional knockout mice display hippocampal atrophy and impaired learning

PDGF‐dependent β‐catenin activation is associated with abnormal pulmonary artery smooth muscle cell proliferation in pulmonary arterial hypertension

The pluripotency transcription factor OCT4 represses heme oxygenase‐1 gene expression

A subset of enteroendocrine cells is activated by amino acids in the Drosophila midgut

Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway

MRP 1 mediates folate transport and antifolate sensitivity in Plasmodium falciparum

The potential role of regulator of G‐protein signaling 16 in cell motility mediated by δ EF 1 family proteins

Letter: gastritis in paediatric patients with coeliac disease

Discovery of N‑(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro‑1H‑pyrrolo[2,3‑c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor

Enabling, Decagram-Scale Synthesis of Macrocyclic MCL‑1 Inhibitor ABBV-467

Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors

C/EBP homologous protein (CHOP) up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform

Influence of Weld Heat Input on the Fracture and Metallurgy of HSLA-65

Discovery and optimization of novel constrained pyrrolopyridone BET family inhibitors

Methylpyrrole inhibitors of BET bromodomains

1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyano- pyrazi-2-yl)ureas as Potent and Selective Inhibitors of Chk1 Kinase: Synthesis, Preliminary SAR, and Biological Activities

2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ETA Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722

An initiator and its flanking elements function as a core promoter driving transcription of the Hepatopoietin gene

Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases

Discovery and Optimization of Anthranilic Acid Sulfonamides as Inhibitors of Methionine Aminopeptidase-2: A Structural Basis for the Reduction of Albumin Binding

Nonpeptide Renin Inhibitors with Good Intraduodenal Bioavailability and Efficacy in Dog

Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids

Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ET A receptor selectivity

C-Terminal modifications of nonpeptide renin inhibitors: improved oral bioavailability via modification of physicochemical properties

Discovery of a series of pyrrolidine-based endothelin receptor antagonists with enhanced ETA receptor selectivity

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