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Linezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive Infections

Journal of medicinal chemistry, 2008-04, Vol.51 (7), p.1981-1990

2008

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Discovery of 6‑(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl‑1H‑indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9768-9772

2015

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Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

Journal of medicinal chemistry, 1996-02, Vol.39 (3), p.673-679

1996

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Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6), p.1478-1483

2017

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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19), p.4824-4828

2016

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7-Oxo-4,7-dihydrothieno[3,2- b]pyridine-6-carboxamides: Synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase

Bioorganic & medicinal chemistry letters, 2007-07, Vol.17 (14), p.3840-3844

2007

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Asymmetric Synthesis of the C3α Fragment of 5,6-Dihydro-α-pyrone Nonpeptidic HIV-1 Protease Inhibitors

Journal of organic chemistry, 1999-06, Vol.64 (13), p.4980-4984

1999

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Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1 H -indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia

Journal of medicinal chemistry, 2015-12, Vol.58 (24), p.9768-9772

2015

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Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6)

2017

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Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2016-10, Vol.26 (19)

2016

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Asymmetric Synthesis of the C3alpha Fragment of 5,6-Dihydro-alpha-pyrone Nonpeptidic HIV-1 Protease Inhibitors

Journal of organic chemistry, 1999-06, Vol.64 (13), p.4980-4984

1999

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PREPARATION OF N-ARYL-5R-HYDROXYMETHYL-2-OXAZOLIDINONES FROM N-ARYL CARBAMATES: N-PHENYL-(5R)-HYDROXYMETHYL- 2-OXAZOLIDINONE

Organic syntheses, 2005, Vol.81, p.112

2005

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N-ACYL 3-ALKYLIDENYL-AND 3-ALKYL AZETIDIN-2-ONES: A NEW CLASS OF MONOCYCLIC β-LACTAM ANTIBACTERIAL AGENTS: 1. STRUCTURE-ACTIVITY RELATIONSHIPS OF 3-ISOPROPYLIDENE AND 3-ISOPROPYL ANALOGS

The Journal of Antibiotics, 1992/02/25, Vol.45(2), pp.213-226

1992

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Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones

Bioorganic & medicinal chemistry letters, 1998-05, Vol.8 (10), p.1231-1236

1998

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N-acyl-3-alkylidenyl- and 3-alkyl azeitidin-2-ones: a new class of monocyclic β-lactam antibacterial agents 2. Synthesis and structure-activity relationships of heteroatom substituted 3-isopropylidene and 3-isopropyl analogs

Bioorganic & medicinal chemistry letters, 1993, Vol.3 (11), p.2241-2246

1993

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TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes

Nature communications, 2019-10, Vol.10 (1), p.4671-4671, Article 4671

2019

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The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease

Journal of Crohn's & colitis, 2016-03, Vol.10 (3), p.239-254

2016

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Author Correction: TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes

Nature communications, 2020-05, Vol.11 (1), p.2387-2387, Article 2387

2020

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Critical assessment of automated flow cytometry data analysis techniques

Nature methods, 2013-03, Vol.10 (3), p.228-238

2013

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European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies

Journal of Crohn's & colitis, 2015-11, Vol.9 (11), p.945-965

2015

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Earth Virtualization Engines (EVE)

Earth system science data, 2024-04, Vol.16 (4), p.2113-2122

2024

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Genome-wide SNP-Based Linkage Scan Identifies a Locus on 8q24 for an Age-Related Hearing Impairment Trait

American journal of human genetics, 2008-09, Vol.83 (3), p.401-407

2008

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Su1316 Unchanged Surgery and Hospitalization Rates in an East-West European Inception Cohort Despite Differences in Use of Biologicals - 3-Year Follow-Up of the ECCO-EpiCom Cohort

Gastroenterology (New York, N.Y. 1943), 2015-04, Vol.148 (4), p.S-472-S-472

2015

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Linezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive Infections

Discovery of 6‑(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl‑1H‑indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia

Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections

Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

7-Oxo-4,7-dihydrothieno[3,2- b]pyridine-6-carboxamides: Synthesis and biological activity of a new class of highly potent inhibitors of human cytomegalovirus DNA polymerase

Asymmetric Synthesis of the C3α Fragment of 5,6-Dihydro-α-pyrone Nonpeptidic HIV-1 Protease Inhibitors

Discovery of 6-(4-{[5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl]methoxy}piperidin-1-yl)-1-methyl-1 H -indole-3-carboxylic Acid: A Novel FXR Agonist for the Treatment of Dyslipidemia

Discovery and characterization of [(cyclopentyl)ethyl]benzoic acid inhibitors of microsomal prostaglandin E synthase-1

Characterization of 3,3-dimethyl substituted N-aryl piperidines as potent microsomal prostaglandin E synthase-1 inhibitors

Asymmetric Synthesis of the C3alpha Fragment of 5,6-Dihydro-alpha-pyrone Nonpeptidic HIV-1 Protease Inhibitors

PREPARATION OF N-ARYL-5R-HYDROXYMETHYL-2-OXAZOLIDINONES FROM N-ARYL CARBAMATES: N-PHENYL-(5R)-HYDROXYMETHYL- 2-OXAZOLIDINONE

N-ACYL 3-ALKYLIDENYL-AND 3-ALKYL AZETIDIN-2-ONES: A NEW CLASS OF MONOCYCLIC β-LACTAM ANTIBACTERIAL AGENTS: 1. STRUCTURE-ACTIVITY RELATIONSHIPS OF 3-ISOPROPYLIDENE AND 3-ISOPROPYL ANALOGS

Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones

N-acyl-3-alkylidenyl- and 3-alkyl azeitidin-2-ones: a new class of monocyclic β-lactam antibacterial agents 2. Synthesis and structure-activity relationships of heteroatom substituted 3-isopropylidene and 3-isopropyl analogs

TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes

The First European Evidence-based Consensus on Extra-intestinal Manifestations in Inflammatory Bowel Disease

Author Correction: TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes

Critical assessment of automated flow cytometry data analysis techniques

European Evidence-based Consensus: Inflammatory Bowel Disease and Malignancies

No general support for functional diversity enhancing resilience across terrestrial plant communities

Earth Virtualization Engines (EVE)

Genome-wide SNP-Based Linkage Scan Identifies a Locus on 8q24 for an Age-Related Hearing Impairment Trait

The Cost of Medical Management, Surgery and Clinical Investigations in a European Population-Based Inception Cohort From the Biological Era: An ECCO-Epicom Study

Su1316 Unchanged Surgery and Hospitalization Rates in an East-West European Inception Cohort Despite Differences in Use of Biologicals - 3-Year Follow-Up of the ECCO-EpiCom Cohort

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