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Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway

PloS one, 2015-10, Vol.10 (10), p.e0139657-e0139657

2015

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Influence of polymorphisms in TNF-α and IL1β on susceptibility to alcohol induced liver diseases and therapeutic potential of miR-124-3p impeding TNF-α/IL1β mediated multi-cellular signaling in liver microenvironment

Frontiers in immunology, 2023-12, Vol.14, p.1241755-1241755

2023

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Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages

PloS one, 2011-04, Vol.6 (4), p.e18467

2011

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AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma

Cancers, 2023-01, Vol.15 (2), p.477

2023

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Malabaricone-A induces a redox imbalance that mediates apoptosis in U937 cell line

PloS one, 2012-05, Vol.7 (5), p.e36938

2012

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Generation of Redox Imbalance Mediates the Cytotoxic Effect of Malabaricone-A in a Multidrug Resistant Cell Line

Anti-cancer agents in medicinal chemistry, 2015-01, Vol.15 (9), p.1156

2015

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Therapeutic targeting of CD38 enhances temozolomide activity in glioblastoma cells and modulates their tumor microenvironment by eliciting an enhanced CD8+ T cell response

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.91-91.21

2020

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Translational development of BAFF-R-specific chimeric antigen receptor T-cell therapy targeting B-cell lymphoid malignancies

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.e19501-e19501

2023

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Prospect of CAR T-cell therapy in acute myeloid leukemia

Expert opinion on investigational drugs, 2022-02, Vol.31 (2), p.211-220

2022

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Translational development of a novel BAFF-R CAR-T therapy targeting B-cell lymphoid malignancies

Cancer Immunology, Immunotherapy, 2023-12, Vol.72 (12), p.4031-4047

2023

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CD38hi B-regulatory (B-reg) cells maintain pathological immune tolerance in chronic lymphocytic leukemia (CLL)/B cell diseases: Potential therapeutic considerations

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.71-71.13

2019

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Lenolidamide and IL-15 enhance natural killer cell-mediated immunity and augments the anti-tumor effect of an anti-CD30/CD16A bispecific antibody against Hodgkin’s lymphoma B-cells

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.71-71.12

2019

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Allylpyrocatechol Attenuates Collagen-Induced Arthritis via Attenuation of Oxidative Stress Secondary to Modulation of the MAPK, JAK/STAT, and Nrf2/HO-1 Pathways

The Journal of pharmacology and experimental therapeutics, 2017-02, Vol.360 (2), p.249

2017

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Oncogenic potential of hepatitis B virus subgenotype D1 surpasses D3: significance in the development of hepatocellular carcinoma

Carcinogenesis (New York), 2018-02, Vol.39 (2), p.283-292

2018

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Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy

Clinical cancer research, 2022-12, Vol.28 (24), p.5455-5468

2022

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Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia

Clinical cancer research, 2019-07, Vol.25 (13), p.3974-3985

2019

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Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay

Journal of fluorine chemistry, 2018-02, Vol.206, p.82-98

2018

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PSMB9 Mediates Resistance to Bortezomib in Multiple Myeloma

Blood, 2017-12, Vol.130, p.3836-3836

2017

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Comparative Analysis on the Anti-Tumor Activity of Venetoclax and Obinutuzumab (VO) Versus Venetoclax and Rituximab (VR) in Primary CLL Cells, Ex Vivo

Blood, 2018-11, Vol.132 (Supplement 1), p.5558-5558

2018

Volltextzugriff (PDF)

Novel tumor-targeted liposomes comprised of an MDM2 antagonist plus proteasome inhibitor display anti-tumor activity in a xenograft model of bortezomib-resistant Waldenstrom macroglobulinemia

Leukemia & lymphoma, 2020-08, Vol.61 (10), p.2399-2408

2020

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CD38-targeted therapy in glioblastoma: A step forward

Journal of clinical oncology, 2018-05, Vol.36 (15_suppl), p.e14030-e14030

2018

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Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells

Immunobiology (1979), 2013-05, Vol.218 (5), p.718-724

2013

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Comparative Analysis of Gene Expression Status to Predict Response to Initial Multiple Myeloma Treatment: Utility of the Mmrf Commpass Database in Validating Historical Findings

Blood, 2017-12, Vol.130, p.2178-2178

2017

Volltextzugriff (PDF)

The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance

Phytomedicine (Stuttgart), 2015-07, Vol.22 (7-8), p.713-723

2015

Volltextzugriff (PDF)

Phase I Study of a Novel Bcl-2 Inhibitor, at-101 in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM)

Blood, 2019-11, Vol.134 (Supplement_1), p.3137-3137

2019

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Andrographolide Analogue Induces Apoptosis and Autophagy Mediated Cell Death in U937 Cells by Inhibition of PI3K/Akt/mTOR Pathway

Influence of polymorphisms in TNF-α and IL1β on susceptibility to alcohol induced liver diseases and therapeutic potential of miR-124-3p impeding TNF-α/IL1β mediated multi-cellular signaling in liver microenvironment

Berberine chloride mediates its anti-leishmanial activity via differential regulation of the mitogen activated protein kinase pathway in macrophages

AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma

Malabaricone-A induces a redox imbalance that mediates apoptosis in U937 cell line

Generation of Redox Imbalance Mediates the Cytotoxic Effect of Malabaricone-A in a Multidrug Resistant Cell Line

Therapeutic targeting of CD38 enhances temozolomide activity in glioblastoma cells and modulates their tumor microenvironment by eliciting an enhanced CD8+ T cell response

Translational development of BAFF-R-specific chimeric antigen receptor T-cell therapy targeting B-cell lymphoid malignancies

Prospect of CAR T-cell therapy in acute myeloid leukemia

Translational development of a novel BAFF-R CAR-T therapy targeting B-cell lymphoid malignancies

CD38hi B-regulatory (B-reg) cells maintain pathological immune tolerance in chronic lymphocytic leukemia (CLL)/B cell diseases: Potential therapeutic considerations

Lenolidamide and IL-15 enhance natural killer cell-mediated immunity and augments the anti-tumor effect of an anti-CD30/CD16A bispecific antibody against Hodgkin’s lymphoma B-cells

Allylpyrocatechol Attenuates Collagen-Induced Arthritis via Attenuation of Oxidative Stress Secondary to Modulation of the MAPK, JAK/STAT, and Nrf2/HO-1 Pathways

Oncogenic potential of hepatitis B virus subgenotype D1 surpasses D3: significance in the development of hepatocellular carcinoma

Lisaftoclax (APG-2575) Is a Novel BCL-2 Inhibitor with Robust Antitumor Activity in Preclinical Models of Hematologic Malignancy

Targeting CD38 Enhances the Antileukemic Activity of Ibrutinib in Chronic Lymphocytic Leukemia

Novel fluorinated curcuminoids and their pyrazole and isoxazole derivatives: Synthesis, structural studies, Computational/Docking and in-vitro bioassay

PSMB9 Mediates Resistance to Bortezomib in Multiple Myeloma

Comparative Analysis on the Anti-Tumor Activity of Venetoclax and Obinutuzumab (VO) Versus Venetoclax and Rituximab (VR) in Primary CLL Cells, Ex Vivo

Novel tumor-targeted liposomes comprised of an MDM2 antagonist plus proteasome inhibitor display anti-tumor activity in a xenograft model of bortezomib-resistant Waldenstrom macroglobulinemia

CD38-targeted therapy in glioblastoma: A step forward

Myeloid derived suppressor cells (MDSCs) can induce the generation of Th17 response from naïve CD4+ T cells

Comparative Analysis of Gene Expression Status to Predict Response to Initial Multiple Myeloma Treatment: Utility of the Mmrf Commpass Database in Validating Historical Findings

The variable chemotherapeutic response of Malabaricone-A in leukemic and solid tumor cell lines depends on the degree of redox imbalance

Phase I Study of a Novel Bcl-2 Inhibitor, at-101 in Combination with Lenalidomide and Dexamethasone in Patients with Relapsed and/or Refractory Multiple Myeloma (RRMM)

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