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Mechanisms and Consequences of Alternative Polyadenylation

Molecular cell, 2011-09, Vol.43 (6), p.853-866

2011

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The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site

Genes & development, 2015-05, Vol.29 (9), p.889-897

2015

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Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

Nature reviews. Molecular cell biology, 2009-11, Vol.10 (11), p.741-754

2009

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RNA-binding proteins in neurodegeneration: mechanisms in aggregate

Genes & development, 2017-08, Vol.31 (15), p.1509-1528

2017

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The RNA polymerase II CTD coordinates transcription and RNA processing

Genes & development, 2012-10, Vol.26 (19), p.2119-2137

2012

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Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

Genes & development, 2010-11, Vol.24 (21), p.2343-2364

2010

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Misregulation of pre-mRNA alternative splicing in cancer

Cancer discovery, 2013-11, Vol.3 (11), p.1228-1237

2013

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Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation

PLoS genetics, 2015-04, Vol.11 (4), p.e1005166-e1005166

2015

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Transcription termination by nuclear RNA polymerases

Genes & development, 2009-06, Vol.23 (11), p.1247-1269

2009

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Molecular basis for the recognition of the human AAUAAA polyadenylation signal

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (7), p.E1419-E1428

2018

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CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing

Genes & development, 2014-11, Vol.28 (21), p.2370-2380

2014

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HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

Nature (London), 2010-01, Vol.463 (7279), p.364-368

2010

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Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses

Cell reports (Cambridge), 2024-03, Vol.43 (3), p.113886-113886, Article 113886

2024

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Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA

Cancer research (Chicago, Ill.), 2010-11, Vol.70 (22), p.8977-8980

2010

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R-loop-mediated genomic instability is caused by impairment of replication fork progression

Genes & development, 2011-10, Vol.25 (19), p.2041-2056

2011

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Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (34), p.E4726-E4734

2015

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XRN2 Links Transcription Termination to DNA Damage and Replication Stress

PLoS genetics, 2016-07, Vol.12 (7), p.e1006107-e1006107

2016

Volltextzugriff (PDF)

Alternative polyadenylation of mRNA precursors

Nature reviews. Molecular cell biology, 2017-01, Vol.18 (1), p.18

2017

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The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains

eLife, 2016-09, Vol.5

2016

Volltextzugriff (PDF)

SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors

Cell reports (Cambridge), 2016-11, Vol.17 (8), p.1990-2003

2016

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Inactivation of the SR Protein Splicing Factor ASF/SF2 Results in Genomic Instability

Cell, 2005-08, Vol.122 (3), p.365-378

2005

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PARP1 Represses PAP and Inhibits Polyadenylation during Heat Shock

Molecular cell, 2013-01, Vol.49 (1), p.7-17

2013

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A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage

Genes & development, 2013-10, Vol.27 (20), p.2227-2232

2013

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RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3' End Processing

Science (American Association for the Advancement of Science), 2011-11, Vol.334 (6056), p.683-686

2011

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SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

Proceedings of the National Academy of Sciences - PNAS, 2022-01, Vol.119 (1)

2022

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Mechanisms and Consequences of Alternative Polyadenylation

The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

RNA-binding proteins in neurodegeneration: mechanisms in aggregate

The RNA polymerase II CTD coordinates transcription and RNA processing

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

Misregulation of pre-mRNA alternative splicing in cancer

Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation

Transcription termination by nuclear RNA polymerases

Molecular basis for the recognition of the human AAUAAA polyadenylation signal

CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing

HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer

Non-canonical isoforms of the mRNA polyadenylation factor WDR33 regulate STING-mediated immune responses

Turning on a Fuel Switch of Cancer: hnRNP Proteins Regulate Alternative Splicing of Pyruvate Kinase mRNA

R-loop-mediated genomic instability is caused by impairment of replication fork progression

Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities

XRN2 Links Transcription Termination to DNA Damage and Replication Stress

Alternative polyadenylation of mRNA precursors

The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains

SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors

Inactivation of the SR Protein Splicing Factor ASF/SF2 Results in Genomic Instability

PARP1 Represses PAP and Inhibits Polyadenylation during Heat Shock

A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage

RNAP II CTD Phosphorylated on Threonine-4 Is Required for Histone mRNA 3' End Processing

SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

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