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Selective Protein Synthesis by Ribosomes with a Drug-Obstructed Exit Tunnel

Cell, 2012-10, Vol.151 (3), p.508-520

2012

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Context-Specific Action of Ribosomal Antibiotics

Annual review of microbiology, 2018-09, Vol.72, p.185

2018

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A synthetic antibiotic class overcoming bacterial multidrug resistance

Nature (London), 2021-11, Vol.599 (7885), p.507-512

2021

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Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action

Annals of the New York Academy of Sciences, 2011-12, Vol.1241 (1), p.33-47

2011

Volltextzugriff (PDF)

Regulation of Gene Expression by Macrolide-Induced Ribosomal Frameshifting

Molecular cell, 2013-12, Vol.52 (5), p.629-642

2013

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Molecular Mechanism of Drug-Dependent Ribosome Stalling

Molecular cell, 2008-04, Vol.30 (2), p.190-202

2008

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Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (43), p.12150-12155

2016

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Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (40), p.17152-17157

2010

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general mode of translation inhibition by macrolide antibiotics

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (45), p.15958-15963

2014

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Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics

Nature communications, 2021-07, Vol.12 (1), p.4466-15, Article 4466

2021

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Engineered ribosomes with tethered subunits for expanding biological function

Nature communications, 2019-09, Vol.10 (1), p.3920-13, Article 3920

2019

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Dynamics of the context-specific translation arrest by chloramphenicol and linezolid

Nature chemical biology, 2020-03, Vol.16 (3), p.310

2020

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A fully orthogonal system for protein synthesis in bacterial cells

Nature communications, 2020-04, Vol.11 (1), p.1858-1858, Article 1858

2020

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Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

Nature structural & molecular biology, 2022-02, Vol.29 (2), p.162

2022

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Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

Nature communications, 2014-03, Vol.5 (1), p.3501-3501, Article 3501

2014

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Macrolide antibiotics allosterically predispose the ribosome for translation arrest

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (27), p.9804-9809

2014

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Assembly and functionality of the ribosome with tethered subunits

Nature communications, 2019-02, Vol.10 (1), p.930-930, Article 930

2019

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Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size

Cell reports (Cambridge), 2016-08, Vol.16 (7), p.1789-1799

2016

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The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

The EMBO journal, 2010-09, Vol.29 (18), p.3108-3117

2010

Volltextzugriff (PDF)

Context-specific action of macrolide antibiotics on the eukaryotic ribosome

Nature communications, 2021-05, Vol.12 (1), p.2803-2803, Article 2803

2021

Volltextzugriff (PDF)

Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center

Molecular cell, 2011-02, Vol.41 (3), p.321-330

2011

Volltextzugriff (PDF)

Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly

Nature communications, 2020-06, Vol.11 (1), p.2900-2900, Article 2900

2020

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Transcriptional and Translational Control of the mlr Operon, Which Confers Resistance to Seven Classes of Protein Synthesis Inhibitors

Antimicrobial Agents and Chemotherapy, 2008-05, Vol.52 (5), p.1703-1712

2008

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Nucleotide biosynthesis is critical for growth of bacteria in human blood

PLoS pathogens, 2008-02, Vol.4 (2), p.e37

2008

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Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis

Antimicrobial Agents and Chemotherapy, 2010-12, Vol.54 (12), p.4961-4970

2010

Volltextzugriff (PDF)

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Selective Protein Synthesis by Ribosomes with a Drug-Obstructed Exit Tunnel

Context-Specific Action of Ribosomal Antibiotics

A synthetic antibiotic class overcoming bacterial multidrug resistance

Macrolide antibiotics in the ribosome exit tunnel: species-specific binding and action

Regulation of Gene Expression by Macrolide-Induced Ribosomal Frameshifting

Molecular Mechanism of Drug-Dependent Ribosome Stalling

Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center

Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action

general mode of translation inhibition by macrolide antibiotics

Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics

Engineered ribosomes with tethered subunits for expanding biological function

Dynamics of the context-specific translation arrest by chloramphenicol and linezolid

A fully orthogonal system for protein synthesis in bacterial cells

Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide

Macrolide antibiotics allosterically predispose the ribosome for translation arrest

Assembly and functionality of the ribosome with tethered subunits

Binding of Macrolide Antibiotics Leads to Ribosomal Selection against Specific Substrates Based on Their Charge and Size

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide

Context-specific action of macrolide antibiotics on the eukaryotic ribosome

Nascent Peptide in the Ribosome Exit Tunnel Affects Functional Properties of the A-Site of the Peptidyl Transferase Center

Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly

Transcriptional and Translational Control of the mlr Operon, Which Confers Resistance to Seven Classes of Protein Synthesis Inhibitors

Nucleotide biosynthesis is critical for growth of bacteria in human blood

Binding and Action of CEM-101, a New Fluoroketolide Antibiotic That Inhibits Protein Synthesis

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