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Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.699-726

2019

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Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Nature chemical biology, 2021-11, Vol.17 (11), p.1157

2021

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Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

Nature communications, 2017-10, Vol.8 (1), p.830-14, Article 830

2017

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Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

Cell chemical biology, 2020-09, Vol.27 (9), p.1164-1180.e5

2020

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Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms

Nature communications, 2022-04, Vol.13 (1), p.2073-2073, Article 2073

2022

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Bifunctional chemical probes inducing protein–protein interactions

Current opinion in chemical biology, 2019-10, Vol.52, p.145-156

2019

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New molecular and therapeutic insights into canine diffuse large B-cell lymphoma elucidates the role of the dog as a model for human disease

Haematologica (Roma), 2019-06, Vol.104 (6), p.e256

2019

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The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type

Exploration of targeted anti-tumor therapy, 2021, Vol.2 (6), p.586-601

2021

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Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Bioorganic & medicinal chemistry, 2019-06, Vol.27 (12), p.2466-2479

2019

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Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader

ACS chemical biology, 2019-05, Vol.14 (5), p.882-892

2019

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Understanding and Improving the Membrane Permeability of VH032-Based PROTACs

ACS medicinal chemistry letters, 2020-09, Vol.11 (9), p.1732-1738

2020

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Targeted protein degradation via intramolecular bivalent glues

Nature (London), 2024-03, Vol.627 (8002), p.204

2024

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New Molecular and Therapeutic Insights into Canine Diffuse Large B Cell Lymphoma Elucidates the Role of the Dog As a Model for Human Disease

Blood, 2018-11, Vol.132 (Supplement 1), p.4173-4173

2018

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Translating PROTAC chemical series optimization into functional outcomes underlying BRD7 and BRD9 protein degradation

Current research in chemical biology, 2021, Vol.1, p.100009, Article 100009

2021

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Trends in Statistical Codicology

Maniaci, Marilena

2021

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From the Thames to the Euphrates de la Tamise à L'Euphrate: Intersecting Perspectives on Greek, Latin and Hebrew Bibles Regards Croisés Sur les Bibles Grecques, Latines et Hébraïques

1, 2023

Volltextzugriff (PDF)

Single‐nucleotide polymorphism in chronic rhinosinusitis: A systematic review

Clinical otolaryngology, 2022-01, Vol.47 (1), p.14-23

2022

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Psychological Counseling among University Students Worldwide: A Systematic Review

European journal of investigation in health, psychology and education, 2023-09, Vol.13 (9), p.1831-1849

2023

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Equus caballus Papillomavirus Type-9 (EcPV9): First Detection in Asymptomatic Italian Horses

Viruses, 2022-09, Vol.14 (9), p.2050

2022

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Resistant and susceptible rainbow trout (Oncorhynchus mykiss) lines show distinctive immune response to Lactococcus garvieae

Fish & shellfish immunology, 2020-10, Vol.105, p.457-468

2020

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Evaluation of internal reference genes for quantitative expression analysis by real-time PCR in ovine whole blood

International journal of molecular sciences, 2011-11, Vol.12 (11), p.7732-7747

2011

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Impact of COVID-19 pandemic on the incidence of otitis media with effusion in adults and children: a multicenter study

European archives of oto-rhino-laryngology, 2022-05, Vol.279 (5), p.2383-2389

2022

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A single nucleotide variant in the promoter region of the CCR5 gene increases susceptibility to arthritis encephalitis virus in goats

BMC veterinary research, 2019-07, Vol.15 (1), p.230-230, Article 230

2019

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Validation of a DNA biochip for species identification in food forensic science

Food control, 2017-08, Vol.78, p.366-373

2017

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Iterative Design and Optimization of Initially Inactive Proteolysis Targeting Chimeras (PROTACs) Identify VZ185 as a Potent, Fast, and Selective von Hippel–Lindau (VHL) Based Dual Degrader Probe of BRD9 and BRD7

Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System

Development of NanoLuc-targeting protein degraders and a universal reporter system to benchmark tag-targeted degradation platforms

Bifunctional chemical probes inducing protein–protein interactions

New molecular and therapeutic insights into canine diffuse large B-cell lymphoma elucidates the role of the dog as a model for human disease

The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type

Cereblon versus VHL: Hijacking E3 ligases against each other using PROTACs

Rapid and Reversible Knockdown of Endogenously Tagged Endosomal Proteins via an Optimized HaloPROTAC Degrader

Understanding and Improving the Membrane Permeability of VH032-Based PROTACs

Targeted protein degradation via intramolecular bivalent glues

New Molecular and Therapeutic Insights into Canine Diffuse Large B Cell Lymphoma Elucidates the Role of the Dog As a Model for Human Disease

Translating PROTAC chemical series optimization into functional outcomes underlying BRD7 and BRD9 protein degradation

Trends in Statistical Codicology

From the Thames to the Euphrates de la Tamise à L'Euphrate: Intersecting Perspectives on Greek, Latin and Hebrew Bibles Regards Croisés Sur les Bibles Grecques, Latines et Hébraïques

Single‐nucleotide polymorphism in chronic rhinosinusitis: A systematic review

Psychological Counseling among University Students Worldwide: A Systematic Review

Equus caballus Papillomavirus Type-9 (EcPV9): First Detection in Asymptomatic Italian Horses

Resistant and susceptible rainbow trout (Oncorhynchus mykiss) lines show distinctive immune response to Lactococcus garvieae

Evaluation of internal reference genes for quantitative expression analysis by real-time PCR in ovine whole blood

Impact of COVID-19 pandemic on the incidence of otitis media with effusion in adults and children: a multicenter study

A single nucleotide variant in the promoter region of the CCR5 gene increases susceptibility to arthritis encephalitis virus in goats

Quality of Life and Excessive Daytime Sleepiness in Adults with Obstructive Sleep Apnea Who Are Treated with Multilevel Surgery or Adherent to Continuous Positive Airway Pressure

Validation of a DNA biochip for species identification in food forensic science

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