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Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers

Cancer discovery, 2018-06, Vol.8 (6), p.686-695

2018

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

The Journal of clinical investigation, 2007-04, Vol.117 (4), p.1068-1077

2007

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Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor-Prolyl Hydroxylase Inhibitor for Anemia

The Journal of pharmacology and experimental therapeutics, 2017-12, Vol.363 (3), p.336-347

2017

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Hypoxic induction of Ctgf is directly mediated by Hif-1

American journal of physiology. Renal physiology, 2004-12, Vol.287 (6), p.F1223-F1232

2004

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Vhlh Gene Deletion Induces Hif-1-Mediated Cell Death in Thymocytes

Molecular and Cellular Biology, 2004-10, Vol.24 (20), p.9038-9047

2004

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Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis : Involvement of mitochondrial inhibition and p53 suppression

Journal of the American Society of Nephrology, 2006-07, Vol.17 (7), p.1875-1885

2006

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Decreased Growth of Vhl−/− Fibrosarcomas Is Associated with Elevated Levels of Cyclin Kinase Inhibitors p21 and p27

Molecular and Cellular Biology, 2005-06, Vol.25 (11), p.4565-4578

2005

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Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent

American journal of physiology. Renal physiology, 2005-12, Vol.289 (6), p.F1217-F1226

2005

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Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas

Biochemical journal, 2004-01, Vol.377 (Pt 2), p.317-326

2004

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Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions

The Journal of clinical investigation, 2004-01, Vol.113 (2), p.285-301

2004

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Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14391-14408

2022

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Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells

Bioorganic & medicinal chemistry letters, 2023-08, Vol.92, p.129385-129385, Article 129385

2023

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Hepatic GABAA receptor functional regulation during rat liver cell proliferation

Hepatology research, 2001-10, Vol.21 (2), p.136-146

2001

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Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c‑MYC Protein Levels in Cells

Journal of medicinal chemistry, 2021-11, Vol.64 (21), p.16056-16087

2021

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Identification and Optimization of Novel Small c‑Abl Kinase Activators Using Fragment and HTS Methodologies

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.2154-2171

2019

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Abstract 1192: Preclinical evaluation of HER3 mutations and rational combinations with AKT inhibition in enhancing anti-tumor activity of HER3 inhibition in gastric cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1192-1192

2016

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Brain stem GABA receptor functional regulation during rat liver cell proliferation

Neurochemical research, 2002-09, Vol.27 (9), p.905-910

2002

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Abstract 2919: Discovery of small-molecule compounds targeting c-MYC using a novel cell-based screen

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2919-2919

2018

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Abstract 1637: MAT2A inhibition in MTAP-/- tumors confers mechanistic vulnerabilities to multiple clinically actionable synthetic lethal drug combinations

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1637-1637

2023

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Hepatic GABA A receptor functional regulation during rat liver cell proliferation

Hepatology research, 2001-10, Vol.21 (2), p.136-146

2001

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Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

Chemistry & biology, 2011-02, Vol.18 (2), p.177-186

2011

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High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells

SLAS discovery, 2021-02, Vol.26 (2), p.216-229

2021

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Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent

American journal of physiology. Renal physiology, 2005-12, Vol.58 (6), p.F1217-F1226

2005

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Decreased Growth of Vhl super(-/-) Fibrosarcomas Is Associated with Elevated Levels of Cyclin Kinase Inhibitors p21 and p27

Molecular and cellular biology, 2005-06, Vol.25 (11), p.4565-4578

2005

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Hypoxic induction of Ctgf is directly mediated by Hif-1

American journal of physiology. Renal physiology, 2004-12, Vol.56 (6), p.F1223-F1232

2004

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Response to ERBB3-Directed Targeted Therapy in NRG1 -Rearranged Cancers

Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor-Prolyl Hydroxylase Inhibitor for Anemia

Hypoxic induction of Ctgf is directly mediated by Hif-1

Vhlh Gene Deletion Induces Hif-1-Mediated Cell Death in Thymocytes

Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis : Involvement of mitochondrial inhibition and p53 suppression

Decreased Growth of Vhl−/− Fibrosarcomas Is Associated with Elevated Levels of Cyclin Kinase Inhibitors p21 and p27

Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent

Characterization of human brain nicotinamide 5'-mononucleotide adenylyltransferase-2 and expression in human pancreas

Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions

Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening

Design and synthesis of aminopyridine containing biaryls reducing c-MYC protein levels in cells

Hepatic GABAA receptor functional regulation during rat liver cell proliferation

Cell-Based Drug Discovery: Identification and Optimization of Small Molecules that Reduce c‑MYC Protein Levels in Cells

Identification and Optimization of Novel Small c‑Abl Kinase Activators Using Fragment and HTS Methodologies

Abstract 1192: Preclinical evaluation of HER3 mutations and rational combinations with AKT inhibition in enhancing anti-tumor activity of HER3 inhibition in gastric cancer

Brain stem GABA receptor functional regulation during rat liver cell proliferation

Abstract 2919: Discovery of small-molecule compounds targeting c-MYC using a novel cell-based screen

Abstract 1637: MAT2A inhibition in MTAP-/- tumors confers mechanistic vulnerabilities to multiple clinically actionable synthetic lethal drug combinations

Hepatic GABA A receptor functional regulation during rat liver cell proliferation

Discovery and Characterization of a Cell-Permeable, Small-Molecule c-Abl Kinase Activator that Binds to the Myristoyl Binding Site

High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells

Protection of HIF-1-deficient primary renal tubular epithelial cells from hypoxia-induced cell death is glucose dependent

Decreased Growth of Vhl super(-/-) Fibrosarcomas Is Associated with Elevated Levels of Cyclin Kinase Inhibitors p21 and p27

Hypoxic induction of Ctgf is directly mediated by Hif-1

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