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Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (17), p.E2253-E2262

2015

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Advances in targeting cyclic nucleotide phosphodiesterases

Nature reviews. Drug discovery, 2014-04, Vol.13 (4), p.290-314

2014

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Tumor Necrosis Factor-α Stimulates Lipolysis in Differentiated Human Adipocytes Through Activation of Extracellular Signal-Related Kinase and Elevation of Intracellular cAMP

Diabetes (New York, N.Y.), 2002-10, Vol.51 (10), p.2929-2935

2002

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Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets

PloS one, 2010-12, Vol.5 (12), p.e14191-e14191

2010

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Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice

The Journal of clinical investigation, 2006-12, Vol.116 (12), p.3240-3251

2006

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Structure, Localization, and Regulation of cGMP-inhibited Phosphodiesterase (PDE3)

The Journal of biological chemistry, 1997-03, Vol.272 (11), p.6823-6826

1997

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Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB

Biochemical journal, 2007-06, Vol.404 (2), p.257-268

2007

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Phosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism

PloS one, 2009-03, Vol.4 (3), p.e4671-e4671

2009

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Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (49), p.19778-19783

2013

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Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3 and Their Contribution to cAMP Hydrolytic Activity in Subcellular Fractions of Human Myocardium

The Journal of biological chemistry, 2005-11, Vol.280 (47), p.39168-39174

2005

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SFPQ, a multifunctional nuclear protein, regulates the transcription of PDE3A

Bioscience reports, 2017-08, Vol.37 (4)

2017

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Phosphodiesterase 3A (PDE3A) Deletion Suppresses Proliferation of Cultured Murine Vascular Smooth Muscle Cells (VSMCs) via Inhibition of Mitogen-activated Protein Kinase (MAPK) Signaling and Alterations in Critical Cell Cycle Regulatory Proteins

The Journal of biological chemistry, 2011-07, Vol.286 (29), p.26238-26249

2011

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Foxp3-dependent programme of regulatory T-cell differentiation

Nature, 2007-02, Vol.445 (7129), p.771-775

2007

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Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3A in Cardiac Myocytes

The Journal of biological chemistry, 2002-10, Vol.277 (41), p.38072-38078

2002

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Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (15), p.6158-6163

2009

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Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST)

Oncotarget, 2017-06, Vol.8 (25), p.41026-41043

2017

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Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue

Scientific reports, 2016-06, Vol.6 (1), p.28056-28056, Article 28056

2016

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White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function

Scientific reports, 2017-01, Vol.7 (1), p.40445-40445, Article 40445

2017

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Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells

Cellular signalling, 2014-09, Vol.26 (9), p.1807-1817

2014

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Modulation of Polycystic Kidney Disease Severity by Phosphodiesterase 1 and 3 Subfamilies

Journal of the American Society of Nephrology, 2016-05, Vol.27 (5), p.1312-1320

2016

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Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

Cellular signalling, 2007-08, Vol.19 (8), p.1765-1771

2007

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Effects of heterologous expression of human cyclic nucleotide phosphodiesterase 3A (hPDE3A) on redox regulation in yeast

Biochemical journal, 2016-11, Vol.473 (22), p.4205-4225

2016

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Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the β3-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes

Biochemical journal, 2009-12, Vol.424 (3), p.399-410

2009

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Dual Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Isoproterenol on Lipid Metabolism and Signaling in Primary Rat Adipocytes

Endocrinology (Philadelphia), 2003-12, Vol.144 (12), p.5293-5299

2003

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Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury

Advances in targeting cyclic nucleotide phosphodiesterases

Tumor Necrosis Factor-α Stimulates Lipolysis in Differentiated Human Adipocytes Through Activation of Extracellular Signal-Related Kinase and Elevation of Intracellular cAMP

Expression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets

Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null mice

Structure, Localization, and Regulation of cGMP-inhibited Phosphodiesterase (PDE3)

Insulin-induced formation of macromolecular complexes involved in activation of cyclic nucleotide phosphodiesterase 3B (PDE3B) and its interaction with PKB

Phosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolism

Selective regulation of cyclic nucleotide phosphodiesterase PDE3A isoforms

Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3 and Their Contribution to cAMP Hydrolytic Activity in Subcellular Fractions of Human Myocardium

SFPQ, a multifunctional nuclear protein, regulates the transcription of PDE3A

Phosphodiesterase 3A (PDE3A) Deletion Suppresses Proliferation of Cultured Murine Vascular Smooth Muscle Cells (VSMCs) via Inhibition of Mitogen-activated Protein Kinase (MAPK) Signaling and Alterations in Critical Cell Cycle Regulatory Proteins

Foxp3-dependent programme of regulatory T-cell differentiation

Isoforms of Cyclic Nucleotide Phosphodiesterase PDE3A in Cardiac Myocytes

Interaction of phosphodiesterase 3A with brefeldin A-inhibited guanine nucleotide-exchange proteins BIG1 and BIG2 and effect on ARF1 activity

Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST)

Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue

White to beige conversion in PDE3B KO adipose tissue through activation of AMPK signaling and mitochondrial function

Role of phosphodiesterase 2 in growth and invasion of human malignant melanoma cells

Modulation of Polycystic Kidney Disease Severity by Phosphodiesterase 1 and 3 Subfamilies

Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice

Effects of heterologous expression of human cyclic nucleotide phosphodiesterase 3A (hPDE3A) on redox regulation in yeast

Differential regulation of adipocyte PDE3B in distinct membrane compartments by insulin and the β3-adrenergic receptor agonist CL316243: effects of caveolin-1 knockdown on formation/maintenance of macromolecular signalling complexes

Dual Effects of Pituitary Adenylate Cyclase-Activating Polypeptide and Isoproterenol on Lipid Metabolism and Signaling in Primary Rat Adipocytes

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