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Cytokine signaling modulates blood-brain barrier function

Current pharmaceutical design, 2011-11, Vol.17 (33), p.3729-3740

2011

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Evaluation of in vitro absorption, distribution, metabolism, and excretion (ADME) properties of mitragynine, 7-hydroxymitragynine, and mitraphylline

Planta medica, 2014-05, Vol.80 (7), p.568-576

2014

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Characterization of in vitro ADME properties of diosgenin and dioscin from Dioscorea villosa

Planta medica, 2013-10, Vol.79 (15), p.1421-1428

2013

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Modulation of Cytochrome P450, P-glycoprotein and Pregnane X Receptor by Selected Antimalarial Herbs-Implication for Herb-Drug Interaction

Molecules (Basel, Switzerland), 2017-11, Vol.22 (12), p.2049

2017

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PXR mediated induction of CYP3A4, CYP1A2, and P‐gp by Mitragyna speciosa and its alkaloids

Phytotherapy research, 2017-12, Vol.31 (12), p.1935-1945

2017

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Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P‑gp

Journal of agricultural and food chemistry, 2019-05, Vol.67 (17), p.4967-4975

2019

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Pharmacokinetics and Tissue Distribution of Aegeline after Oral Administration in Mice

Planta medica, 2019-04, Vol.85 (6), p.491-495

2019

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Modulation of CYPs, P-gp, and PXR by Eschscholzia californica (California Poppy) and Its Alkaloids

Planta medica, 2016-04, Vol.82 (6), p.551-558

2016

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Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway

Xenobiotica, 2015-03, Vol.45 (3), p.218-229

2015

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Pharmacokinetics and cytotoxic study of euphol from Euphorbia umbellata (Bruyns) Pax latex

Phytomedicine (Stuttgart), 2018-08, Vol.47, p.105-112

2018

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Chronic exposure to nicotine and saquinavir decreases endothelial Notch‐4 expression and disrupts blood‐brain barrier integrity

Journal of neurochemistry, 2010-10, Vol.115 (2), p.515-525

2010

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Quantification of mesembrine and mesembrenone in mouse plasma using UHPLC‐QToF‐MS: Application to a pharmacokinetic study

Biomedical chromatography, 2017-03, Vol.31 (3), p.np-n/a

2017

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P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

Frontiers in pharmacology, 2013-01, Vol.4, p.136-136

2013

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Nicotine and cotinine increases the brain penetration of saquinavir in rat

Journal of neurochemistry, 2010-12, Vol.115 (6), p.1495-1507

2010

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In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities

Drug metabolism letters, 2015-01, Vol.9 (1), p.48-62

2015

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Inhibition of CYP3A4 and CYP1A2 by Aegle marmelos and its constituents

Xenobiotica, 2016-02, Vol.46 (2), p.117-125

2016

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Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A

Journal of ethnopharmacology, 2017-02, Vol.197, p.211-217

2017

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Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood–brain barrier

Journal of neuroscience methods, 2013-09, Vol.219 (1), p.188-195

2013

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Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents

Frontiers in pharmacology, 2014-08, Vol.5, p.178

2014

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N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity

The Journal of pharmacology and experimental therapeutics, 2008-08, Vol.326 (2), p.563-576

2008

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Exploiting nutrient transporters at the blood-brain barrier to improve brain distribution of small molecules

Therapeutic delivery, 2010-12, Vol.1 (6), p.775-784

2010

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Predictive screening model for potential vector-mediated transport of cationic substrates at the blood–brain barrier choline transporter

Bioorganic & medicinal chemistry letters, 2010-02, Vol.20 (3), p.870-877

2010

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Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine

Medicines (Basel, Switzerland), 2015-06, Vol.2 (2), p.93-105

2015

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Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier

The Journal of pharmacology and experimental therapeutics, 2008-01, Vol.324 (1), p.244-250

2008

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Bulbine natalensis (currently Bulbine latifolia) and select bulbine knipholones modulate the activity of AhR, CYP1A2, CYP2B6, and P-gp

Planta medica, 2022-10, Vol.88 (12), p.975-984

2022

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Cytokine signaling modulates blood-brain barrier function

Evaluation of in vitro absorption, distribution, metabolism, and excretion (ADME) properties of mitragynine, 7-hydroxymitragynine, and mitraphylline

Characterization of in vitro ADME properties of diosgenin and dioscin from Dioscorea villosa

Modulation of Cytochrome P450, P-glycoprotein and Pregnane X Receptor by Selected Antimalarial Herbs-Implication for Herb-Drug Interaction

PXR mediated induction of CYP3A4, CYP1A2, and P‐gp by Mitragyna speciosa and its alkaloids

Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) through Interaction with CYP, PXR, and P‑gp

Pharmacokinetics and Tissue Distribution of Aegeline after Oral Administration in Mice

Modulation of CYPs, P-gp, and PXR by Eschscholzia californica (California Poppy) and Its Alkaloids

Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway

Pharmacokinetics and cytotoxic study of euphol from Euphorbia umbellata (Bruyns) Pax latex

Chronic exposure to nicotine and saquinavir decreases endothelial Notch‐4 expression and disrupts blood‐brain barrier integrity

Quantification of mesembrine and mesembrenone in mouse plasma using UHPLC‐QToF‐MS: Application to a pharmacokinetic study

P-glycoprotein mediated efflux limits substrate and drug uptake in a preclinical brain metastases of breast cancer model

Nicotine and cotinine increases the brain penetration of saquinavir in rat

In Vitro Evaluation of Reversible and Time-Dependent Inhibitory Effects of Kalanchoe crenata on CYP2C19 and CYP3A4 Activities

Inhibition of CYP3A4 and CYP1A2 by Aegle marmelos and its constituents

Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A

Quantitative fluorescence microscopy provides high resolution imaging of passive diffusion and P-gp mediated efflux at the in vivo blood–brain barrier

Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents

N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity

Exploiting nutrient transporters at the blood-brain barrier to improve brain distribution of small molecules

Predictive screening model for potential vector-mediated transport of cationic substrates at the blood–brain barrier choline transporter

Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine

Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier

Bulbine natalensis (currently Bulbine latifolia) and select bulbine knipholones modulate the activity of AhR, CYP1A2, CYP2B6, and P-gp

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