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Understanding TERT Promoter Mutations: A Common Path to Immortality

Molecular cancer research, 2016-04, Vol.14 (4), p.315-323

2016

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The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Science (American Association for the Advancement of Science), 2015-05, Vol.348 (6238), p.1036-1039

2015

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Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

Cancer cell, 2018-09, Vol.34 (3), p.513-528.e8

2018

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ORAOV1, CCND1, and MIR548K Are the Driver Oncogenes of the 11q13 Amplicon in Squamous Cell Carcinoma

Molecular cancer research, 2024-02, Vol.22 (2), p.152-168

2024

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Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

Molecular cancer, 2023-06, Vol.22 (1), p.100-100, Article 100

2023

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Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process

Cancer research (Chicago, Ill.), 2016-11, Vol.76 (22), p.6680-6689

2016

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Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

Proceedings of the National Academy of Sciences - PNAS, 2021-03, Vol.118 (13)

2021

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Abstract 1474: Hippo-mediated control of the mutant TERT promoter via MYC and GABP

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1474-1474

2023

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GENE-43. TARGETING GABPb1L INHIBITS IN VIVO GROWTH OF TERT PROMOTER MUTANT GLIOBLASTOMA

Neuro-oncology (Charlottesville, Va.), 2019-11, Vol.21 (Supplement_6), p.vi106-vi107

2019

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Reducing risk for cell therapy manufacturing with a battle-tested electroporation platform

Cell and Gene Therapy Insights, 2023-08, Vol.9 (5), p.809-809

Mancini, Andrew

2023

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Evaluation of Post-Stroke Facial Movements Using 3D Depth-Sensing Facial Motion Tracking

Mancini, Andrew

2018

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CSIG-38. REVERSAL OF GLIOBLASTOMA REPLICATIVE IMMORTALITY IN A TERT PROMOTER MUTATION-DEPENDENT MANNER

Neuro-oncology (Charlottesville, Va.), 2017-11, Vol.19 (suppl_6), p.vi57-vi58

2017

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CBIO-18. HAPLOINSUFFICIENCY OF THE REGULATOR OF THE MUTANT TERT PROMOTER REVERSES GLIOBLASTOMA REPLICATIVE IMMORTALITY

Neuro-oncology (Charlottesville, Va.), 2016-11, Vol.18 (suppl_6), p.vi39-vi39

2016

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Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis

Blood advances, 2023-02, Vol.7 (4), p.491-507

2023

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Regulation of Replicative Immortality by GABPβ1L in TERT Promoter Mutant Glioblastoma

Mancini, Andrew Guy

2018

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CBIO-02. MUTANT IDH EXPRESSION DRIVES TERT PROMOTER REACTIVATION AS PART OF THE CELLULAR TRANSFORMATION PROCESS

Neuro-oncology (Charlottesville, Va.), 2016-11, Vol.18 (suppl_6), p.vi35-vi35

2016

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Abstract B12: GABP selectively binds and activates the mutant TERT promoter across multiple cancer types

Cancer research (Chicago, Ill.), 2015-12, Vol.75 (23_Supplement), p.B12-B12

2015

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GENO-07A MECHANISM OF MUTANT TERT PROMOTER ACTIVATION SHARED ACROSS CANCER TYPES

Neuro-oncology (Charlottesville, Va.), 2015-11, Vol.17 (suppl 5), p.v92.3-v92

2015

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Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Science (American Association for the Advancement of Science), 2015-05, Vol.348 (6238), p.1036-1039

2015

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Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence

Journal of the American College of Cardiology, 2017-08, Vol.70 (9), p.1148-1158

2017

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Angiographic appearance of spontaneous coronary artery dissection with intramural hematoma proven on intracoronary imaging

Catheterization and cardiovascular interventions, 2016-02, Vol.87 (2), p.E54-E61

2016

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Spontaneous Coronary Artery Dissection: Association With Predisposing Arteriopathies and Precipitating Stressors and Cardiovascular Outcomes

Circulation. Cardiovascular interventions, 2014-10, Vol.7 (5), p.645-655

2014

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Bioimaging Second window for in vivo imaging

Nature nanotechnology, 2009-11, Vol.4 (11), p.710-711

2009

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Catheter-Induced Iatrogenic Coronary Artery Dissection in Patients With Spontaneous Coronary Artery Dissection

JACC. Cardiovascular interventions, 2016-09, Vol.9 (17), p.1851-1853

2016

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Understanding TERT Promoter Mutations: A Common Path to Immortality

Antibody targeting of E3 ubiquitin ligases for receptor degradation

The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner

ORAOV1, CCND1, and MIR548K Are the Driver Oncogenes of the 11q13 Amplicon in Squamous Cell Carcinoma

Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing

Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

Abstract 1474: Hippo-mediated control of the mutant TERT promoter via MYC and GABP

GENE-43. TARGETING GABPb1L INHIBITS IN VIVO GROWTH OF TERT PROMOTER MUTANT GLIOBLASTOMA

Reducing risk for cell therapy manufacturing with a battle-tested electroporation platform

Evaluation of Post-Stroke Facial Movements Using 3D Depth-Sensing Facial Motion Tracking

CSIG-38. REVERSAL OF GLIOBLASTOMA REPLICATIVE IMMORTALITY IN A TERT PROMOTER MUTATION-DEPENDENT MANNER

CBIO-18. HAPLOINSUFFICIENCY OF THE REGULATOR OF THE MUTANT TERT PROMOTER REVERSES GLIOBLASTOMA REPLICATIVE IMMORTALITY

Disruption of stem cell niche–confined R-spondin 3 expression leads to impaired hematopoiesis

Regulation of Replicative Immortality by GABPβ1L in TERT Promoter Mutant Glioblastoma

CBIO-02. MUTANT IDH EXPRESSION DRIVES TERT PROMOTER REACTIVATION AS PART OF THE CELLULAR TRANSFORMATION PROCESS

Abstract B12: GABP selectively binds and activates the mutant TERT promoter across multiple cancer types

GENO-07A MECHANISM OF MUTANT TERT PROMOTER ACTIVATION SHARED ACROSS CANCER TYPES

Cancer. The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer

Spontaneous Coronary Artery Dissection: Clinical Outcomes and Risk of Recurrence

Angiographic appearance of spontaneous coronary artery dissection with intramural hematoma proven on intracoronary imaging

Spontaneous Coronary Artery Dissection: Association With Predisposing Arteriopathies and Precipitating Stressors and Cardiovascular Outcomes

Bioimaging Second window for in vivo imaging

Catheter-Induced Iatrogenic Coronary Artery Dissection in Patients With Spontaneous Coronary Artery Dissection

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