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Kinetic and Data-Driven Reaction Analysis for Pharmaceutical Process Development

Industrial & engineering chemistry research, 2020-02, Vol.59 (6), p.2409-2421

2020

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Development of an Efficient Synthesis of the Pyrrolquinolone PHA-529311

Organic process research & development, 2006-05, Vol.10 (3), p.493-499

2006

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Development and Application of Laboratory Tools To Predict Particle Properties upon Scale-Up in Agitated Filter-Dryers

Organic process research & development, 2013-10, Vol.17 (10), p.1345-1358

2013

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Ir-Catalyzed Borylation as an Efficient Route to a Nicotine Hapten

Organic process research & development, 2018-04, Vol.22 (4), p.527-534

2018

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Special Feature Section: Engineering Contributions to Process Chemistry

Organic process research & development, 2015-09, Vol.19 (9), p.1075-1075

2015

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Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability

Organic process research & development, 2016-07, Vol.20 (7), p.1203-1216

2016

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The Synthesis of OSU 6162: Efficient, Large-Scale Implementation of a Suzuki Coupling

Organic process research & development, 2003-05, Vol.7 (3), p.385-392

2003

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Special Feature Section: Engineering Contributions to Chemical Process Development

Organic process research & development, 2013-10, Vol.17 (10), p.1261-1261

2013

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Chromatography- and Lyophilization-Free Synthesis of a Peptide-Linker Conjugate

Organic process research & development, 2014-01, Vol.18 (1), p.142-151

2014

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Synthesis of a novel analytical reagent for the determination of active sites for conjugation on a catalytic aldolase monoclonal antibody

Tetrahedron letters, 2012-03, Vol.53 (11), p.1385-1389

2012

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Chemoselective Saponification in the Synthesis of Danuglipron Facilitated with Trifluoroethanol

Organic process research & development, 2024-07, Vol.28 (7), p.2702-2707

2024

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Development of a Pilot-Scale Preparation of N-[[(5S)-3-[4-(1,1-Dioxido-4- thiomorpholinyl)-3,5-difluorophenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide, PNU-288034, an Oxazolidinone Antibacterial Agent

Organic process research & development, 2006-03, Vol.10 (2), p.272-277

2006

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Process Development and Scale-Up of the Potential Thiazolidinedione Antidiabetic Candidate PNU-91325

Organic process research & development, 2002-09, Vol.6 (5), p.721-728

2002

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Scalable and Cost-Effective Synthesis of a Linker for Bioconjugation with a Peptide and a Monoclonal Antibody

Synthesis (Stuttgart), 2014-06, Vol.46 (10), p.1399-1406

2014

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Synthesis of an H 3 Antagonist via Sequential One-Pot Additions of a Magnesium Ate Complex and an Amine to a 1,4-Ketoester followed by Carbonyl-Directed Fluoride Addition

Organic process research & development, 2012-08, Vol.16 (8), p.1393-1403

2012

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The Synthesis of N-Aryl-5(S)-aminomethyl-2-oxazolidinone Antibacterials and Derivatives in One Step from Aryl Carbamates

Organic process research & development, 2003-07, Vol.7 (4), p.533-546

2003

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Synthesis of an H3 Antagonist via Sequential One-Pot Additions of a Magnesium Ate Complex and an Amine to a 1,4-Ketoester followed by Carbonyl-Directed Fluoride Addition

Organic process research & development, 2012-08, Vol.16 (8), p.1393-1403

2012

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Dilute acid hydrolysis of paper birch: kinetics studies of xylan and acetyl-group hydrolysis

Biotechnology and bioengineering, 1985-03, Vol.27 (3), p.355-361

1985

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An engineering analysis of the production of xylose by dilute acid hydrolysis of hardwood hemicellulose

Biotechnology progress, 1986-12, Vol.2 (4), p.192-202

1986

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KDM5 histone demethylases repress immune response via suppression of STING

PLoS biology, 2018-08, Vol.16 (8), p.e2006134

2018

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Nitric Oxide Therapy for Diabetic Wound Healing

Advanced healthcare materials, 2019-06, Vol.8 (12), p.e1801210-n/a

2019

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Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6470), p.1255-1259

2019

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Avalanches in strained amorphous solids: does inertia destroy critical behavior?

Physical review letters, 2012-09, Vol.109 (10), p.105703-105703, Article 105703

2012

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Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy

Nature communications, 2020-01, Vol.11 (1), p.219-13, Article 219

2020

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Episodic Ultradian Events-Ultradian Rhythms

Biology (Basel, Switzerland), 2019-03, Vol.8 (1), p.15

2019

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Kinetic and Data-Driven Reaction Analysis for Pharmaceutical Process Development

Development of an Efficient Synthesis of the Pyrrolquinolone PHA-529311

Development and Application of Laboratory Tools To Predict Particle Properties upon Scale-Up in Agitated Filter-Dryers

Ir-Catalyzed Borylation as an Efficient Route to a Nicotine Hapten

Special Feature Section: Engineering Contributions to Process Chemistry

Palbociclib Commercial Manufacturing Process Development. Part II: Regioselective Heck Coupling with Polymorph Control for Processability

The Synthesis of OSU 6162: Efficient, Large-Scale Implementation of a Suzuki Coupling

Special Feature Section: Engineering Contributions to Chemical Process Development

Chromatography- and Lyophilization-Free Synthesis of a Peptide-Linker Conjugate

Synthesis of a novel analytical reagent for the determination of active sites for conjugation on a catalytic aldolase monoclonal antibody

Chemoselective Saponification in the Synthesis of Danuglipron Facilitated with Trifluoroethanol

Development of a Pilot-Scale Preparation of N-[[(5S)-3-[4-(1,1-Dioxido-4- thiomorpholinyl)-3,5-difluorophenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide, PNU-288034, an Oxazolidinone Antibacterial Agent

Process Development and Scale-Up of the Potential Thiazolidinedione Antidiabetic Candidate PNU-91325

Scalable and Cost-Effective Synthesis of a Linker for Bioconjugation with a Peptide and a Monoclonal Antibody

Synthesis of an H 3 Antagonist via Sequential One-Pot Additions of a Magnesium Ate Complex and an Amine to a 1,4-Ketoester followed by Carbonyl-Directed Fluoride Addition

The Synthesis of N-Aryl-5(S)-aminomethyl-2-oxazolidinone Antibacterials and Derivatives in One Step from Aryl Carbamates

Synthesis of an H3 Antagonist via Sequential One-Pot Additions of a Magnesium Ate Complex and an Amine to a 1,4-Ketoester followed by Carbonyl-Directed Fluoride Addition

Dilute acid hydrolysis of paper birch: kinetics studies of xylan and acetyl-group hydrolysis

An engineering analysis of the production of xylose by dilute acid hydrolysis of hardwood hemicellulose

KDM5 histone demethylases repress immune response via suppression of STING

Nitric Oxide Therapy for Diabetic Wound Healing

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Avalanches in strained amorphous solids: does inertia destroy critical behavior?

Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy

Episodic Ultradian Events-Ultradian Rhythms

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