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Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

Cell host & microbe, 2015-03, Vol.17 (3), p.357-368

2015

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Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

Cell, 2015-07, Vol.162 (1), p.45-58

2015

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Caspases in Cell Death, Inflammation, and Pyroptosis

Annual review of immunology, 2020-04, Vol.38 (1), p.567-595

2020

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Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Cell, 2021-01, Vol.184 (1), p.149-168.e17

2021

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The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation

Immunity (Cambridge, Mass.), 2018-07, Vol.49 (1), p.56-65.e4

2018

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Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease

The Journal of experimental medicine, 2020-03, Vol.217 (3)

2020

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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

Cell reports (Cambridge), 2021-10, Vol.37 (3), p.109858-109858, Article 109858

2021

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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

Immunity (Cambridge, Mass.), 2018-09, Vol.49 (3), p.515-530.e5

2018

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TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation

The Journal of experimental medicine, 2018-04, Vol.215 (4), p.1023-1034

2018

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IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation

Cell, 2018-05, Vol.173 (4), p.920-933.e13

2018

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ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death

The Journal of experimental medicine, 2017-08, Vol.214 (8), p.2217-2229

2017

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IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

Cell, 2016-10, Vol.167 (2), p.382-396.e17

2016

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GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever

The Journal of experimental medicine, 2018-06, Vol.215 (6), p.1519-1529

2018

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The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

Cancer cell, 2011-11, Vol.20 (5), p.649-660

2011

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Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection

The Journal of experimental medicine, 2016-09, Vol.213 (10), p.2081-2097

2016

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Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection

Cell reports (Cambridge), 2018-03, Vol.22 (12), p.3168-3174

2018

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Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

Frontiers in immunology, 2022-11, Vol.13, p.1068230

2022

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Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis

iScience, 2023-06, Vol.26 (6), p.106938, Article 106938

2023

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Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection

The Journal of biological chemistry, 2020-10, Vol.295 (41), p.14040-14052

2020

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NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

Cell, 2023-06, Vol.186 (13), p.2783-2801.e20

2023

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The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

Nature immunology, 2015-05, Vol.16 (5), p.467-475

2015

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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

Nature (London), 2019-09, Vol.573 (7775), p.590-594

2019

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NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

Nature (London), 2016-12, Vol.540 (7634), p.583-587

2016

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NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

Nature (London), 2012-08, Vol.488 (7411), p.389-393

2012

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Innate Immunity in Protection and Pathogenesis During Coronavirus Infections and COVID-19

Annual review of immunology, 2024-06, Vol.42 (1), p.615-645

2024

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Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

Caspases in Cell Death, Inflammation, and Pyroptosis

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

The TWIK2 Potassium Efflux Channel in Macrophages Mediates NLRP3 Inflammasome-Induced Inflammation

Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease

ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation

IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever

The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection

Detrimental Type I Interferon Signaling Dominates Protective AIM2 Inflammasome Responses during Francisella novicida Infection

Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

Whole-genome CRISPR screen identifies RAVER1 as a key regulator of RIPK1-mediated inflammatory cell death, PANoptosis

Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection

NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs

The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection

DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer

NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens

Innate Immunity in Protection and Pathogenesis During Coronavirus Infections and COVID-19

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