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Peptide modification and cyclization via transition-metal catalysis

Current opinion in chemical biology, 2018-10, Vol.46, p.25-32

Malins, Lara R

2018

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Electrochemistry for the Chemoselective Modification of Peptides and Proteins

Journal of the American Chemical Society, 2022-01, Vol.144 (1), p.23-41

2022

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A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents

Science (American Association for the Advancement of Science), 2016-05, Vol.352 (6287), p.801-805

2016

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Recent extensions to native chemical ligation for the chemical synthesis of peptides and proteins

Current opinion in chemical biology, 2014-10, Vol.22, p.70-78

2014

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Strain-release amination

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6270), p.241-246

2016

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Nickel‐Catalyzed Barton Decarboxylation and Giese Reactions: A Practical Take on Classic Transforms

Angewandte Chemie International Edition, 2017-01, Vol.56 (1), p.260-265

International ed. in English, 2017

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Decarboxylative Alkynylation

Angewandte Chemie International Edition, 2017-09, Vol.56 (39), p.11906-11910

International ed. in English, 2017

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Decarboxylative couplings as versatile tools for late‐stage peptide modifications

Peptide science (Hoboken, N.J.), 2018-05, Vol.110 (3), p.n/a

Malins, Lara R.

2018

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Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity

Journal of the American Chemical Society, 2017-03, Vol.139 (8), p.3209-3226

2017

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Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products

Journal of the American Chemical Society, 2017-04, Vol.139 (14), p.5233-5241

2017

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Investigating Bicyclobutane–Triazolinedione Cycloadditions as a Tool for Peptide Modification

Organic letters, 2022-02, Vol.24 (6), p.1268-1273

2022

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Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine

Angewandte Chemie (International ed.), 2015-10, Vol.54 (43), p.12716-12721

International ed. in English, 2015

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Fine-Tuning Electroauxiliary-Mediated Peptide Modifications Using Second-Generation Electroactive Amino Acids

Organic letters, 2023-05, Vol.25 (20), p.3633-3638

2023

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Late‐Stage Functionalization of Histidine in Unprotected Peptides

Angewandte Chemie International Edition, 2019-12, Vol.58 (52), p.19096-19102

International ed. in English, 2019

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Structurally Diverse Acyl Bicyclobutanes: Valuable Strained Electrophiles

Chemistry : a European journal, 2020-03, Vol.26 (13), p.2808-2812

2020

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Self-Adjuvanting Multicomponent Cancer Vaccine Candidates Combining Per-Glycosylated MUC1 Glycopeptides and the Toll-like Receptor 2 Agonist Pam₃CysSer

Angewandte Chemie (International ed.), 2011-02, Vol.50 (7), p.1635-1639

International ed. in English, 2011

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Residue-Specific Peptide Modification: A Chemist’s Guide

Biochemistry (Easton), 2017-08, Vol.56 (30), p.3863-3873

2017

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Peptide ligation chemistry at selenol amino acids

Journal of peptide science, 2014-02, Vol.20 (2), p.64-77

2014

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An Electrochemical Approach to Designer Peptide α‑Amides Inspired by α‑Amidating Monooxygenase Enzymes

Journal of the American Chemical Society, 2021-08, Vol.143 (30), p.11811-11819

2021

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Radical Reactions for the Construction and Transformation of Complex Molecules

Organic letters, 2024-09, Vol.26 (37), p.7775-7777

2024

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Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Chemical communications (Cambridge, England), 2016-01, Vol.52 (88), p.12952-12955

2016

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Total synthesis of biseokeaniamides A-C and late-stage electrochemically-enabled peptide analogue synthesis

Chemical science (Cambridge), 2020-07, Vol.11 (39), p.1752-1758

2020

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Synthesis of Amino Acid α‑Thioethers and Late-Stage Incorporation into Peptides

Organic letters, 2022-05, Vol.24 (20), p.3680-3685

2022

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Decarboxylative alkenylation

Nature (London), 2017-05, Vol.545 (7653), p.213-218

2017

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Umpolung strategies for the functionalization of peptides and proteins

Chemical science (Cambridge), 2022-03, Vol.13 (10), p.2809-2823

2022

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Peptide modification and cyclization via transition-metal catalysis

Electrochemistry for the Chemoselective Modification of Peptides and Proteins

A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagents

Recent extensions to native chemical ligation for the chemical synthesis of peptides and proteins

Strain-release amination

Nickel‐Catalyzed Barton Decarboxylation and Giese Reactions: A Practical Take on Classic Transforms

Decarboxylative Alkynylation

Decarboxylative couplings as versatile tools for late‐stage peptide modifications

Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity

Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products

Investigating Bicyclobutane–Triazolinedione Cycloadditions as a Tool for Peptide Modification

Oxidative Deselenization of Selenocysteine: Applications for Programmed Ligation at Serine

Fine-Tuning Electroauxiliary-Mediated Peptide Modifications Using Second-Generation Electroactive Amino Acids

Late‐Stage Functionalization of Histidine in Unprotected Peptides

Structurally Diverse Acyl Bicyclobutanes: Valuable Strained Electrophiles

Self-Adjuvanting Multicomponent Cancer Vaccine Candidates Combining Per-Glycosylated MUC1 Glycopeptides and the Toll-like Receptor 2 Agonist Pam₃CysSer

Residue-Specific Peptide Modification: A Chemist’s Guide

Peptide ligation chemistry at selenol amino acids

An Electrochemical Approach to Designer Peptide α‑Amides Inspired by α‑Amidating Monooxygenase Enzymes

Radical Reactions for the Construction and Transformation of Complex Molecules

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Total synthesis of biseokeaniamides A-C and late-stage electrochemically-enabled peptide analogue synthesis

Synthesis of Amino Acid α‑Thioethers and Late-Stage Incorporation into Peptides

Decarboxylative alkenylation

Umpolung strategies for the functionalization of peptides and proteins

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