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Siderophore conjugates

Annals of the New York Academy of Sciences, 2013-01, Vol.1277 (1), p.115-126

Page, Malcolm G. P.

2013

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In Vitro Properties of BAL30072, a Novel Siderophore Sulfactam with Activity against Multiresistant Gram-Negative Bacilli

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2291-2302

2010

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Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii

Antimicrobial agents and chemotherapy, 2017-04, Vol.61 (4)

2017

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What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles

Journal of Pharmacokinetics and Pharmacodynamics, 2017-04, Vol.44 (2), p.113-132

2017

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A Unified Numbering Scheme for Class C β-Lactamases

Antimicrobial agents and chemotherapy, 2020-02, Vol.64 (3)

Page, Malcolm G P

2020

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Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes

Antimicrobial agents and chemotherapy, 2021-01, Vol.65 (2)

2021

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Involvement of Fe Uptake Systems and AmpC β-Lactamase in Susceptibility to the Siderophore Monosulfactam BAL30072 in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 2013-05, Vol.57 (5), p.2095-2102

2013

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Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2621-2624

2007

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The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

Nature communications, 2019-08, Vol.10 (1), p.3673-14, Article 3673

2019

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High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa

PloS one, 2014-10, Vol.9 (10), p.e111311

2014

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Discovery and development of new antibacterial agents targeting Gram-negative bacteria in the era of pandrug resistance: is the future promising?

Current opinion in pharmacology, 2014-10, Vol.18, p.91-97

2014

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The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD Is Required for Uptake of Peptidyl Nucleoside Antibiotics

Journal of bacteriology, 2015-07, Vol.197 (13), p.2217-2228

2015

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Prospects for the next anti- Pseudomonas drug

Current opinion in pharmacology, 2009-10, Vol.9 (5), p.558-565

2009

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In vitro activity of the siderophore monosulfactam BAL30072 against meropenem-non-susceptible Acinetobacter baumannii

Journal of antimicrobial chemotherapy, 2012-05, Vol.67 (5), p.1167-1169

2012

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In Vitro and In Vivo Properties of BAL30376, a β-Lactam and Dual β-Lactamase Inhibitor Combination with Enhanced Activity against Gram-Negative Bacilli That Express Multiple β-Lactamases

Antimicrobial Agents and Chemotherapy, 2011-04, Vol.55 (4), p.1510-1519

2011

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Penicillin-binding proteins: evergreen drug targets

Current opinion in pharmacology, 2014-10, Vol.18, p.112-119

2014

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Synthesis and Characterization of the Arylomycin Lipoglycopeptide Antibiotics and the Crystallographic Analysis of Their Complex with Signal Peptidase

Journal of the American Chemical Society, 2011-11, Vol.133 (44), p.17869-17877

2011

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Interactions of Ceftobiprole with β-Lactamases from Molecular Classes A to D

Antimicrobial Agents and Chemotherapy, 2007-09, Vol.51 (9), p.3089-3095

2007

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In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii

Journal of antimicrobial chemotherapy, 2011-04, Vol.66 (4), p.867-873

2011

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In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan

International journal of antimicrobial agents, 2010-10, Vol.36 (4), p.324-331

2010

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Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen Acinetobacter baumannii

eLife, 2018-12, Vol.7

2018

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Impact of Specific pbp5 Mutations on Expression of β-Lactam Resistance in Enterococcus faecium

Antimicrobial Agents and Chemotherapy, 2004-08, Vol.48 (8), p.3028-3032

2004

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In vitro activity of BAL30072 against Burkholderia pseudomallei

International journal of antimicrobial agents, 2011-08, Vol.38 (2), p.157-159

2011

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Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

Biomolecules (Basel, Switzerland), 2020-06, Vol.10 (6), p.899

2020

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Siderophore conjugates

In Vitro Properties of BAL30072, a Novel Siderophore Sulfactam with Activity against Multiresistant Gram-Negative Bacilli

Structure and Function of the PiuA and PirA Siderophore-Drug Receptors from Pseudomonas aeruginosa and Acinetobacter baumannii

What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles

A Unified Numbering Scheme for Class C β-Lactamases

Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes

Involvement of Fe Uptake Systems and AmpC β-Lactamase in Susceptibility to the Siderophore Monosulfactam BAL30072 in Pseudomonas aeruginosa

Binding of Ceftobiprole and Comparators to the Penicillin-Binding Proteins of Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae

The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model

High-throughput screening of dipeptide utilization mediated by the ABC transporter DppBCDF and its substrate-binding proteins DppA1-A5 in Pseudomonas aeruginosa

Discovery and development of new antibacterial agents targeting Gram-negative bacteria in the era of pandrug resistance: is the future promising?

The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD Is Required for Uptake of Peptidyl Nucleoside Antibiotics

Prospects for the next anti- Pseudomonas drug

In vitro activity of the siderophore monosulfactam BAL30072 against meropenem-non-susceptible Acinetobacter baumannii

In Vitro and In Vivo Properties of BAL30376, a β-Lactam and Dual β-Lactamase Inhibitor Combination with Enhanced Activity against Gram-Negative Bacilli That Express Multiple β-Lactamases

Penicillin-binding proteins: evergreen drug targets

Synthesis and Characterization of the Arylomycin Lipoglycopeptide Antibiotics and the Crystallographic Analysis of Their Complex with Signal Peptidase

Interactions of Ceftobiprole with β-Lactamases from Molecular Classes A to D

In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii

Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions

In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan

Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen Acinetobacter baumannii

Impact of Specific pbp5 Mutations on Expression of β-Lactam Resistance in Enterococcus faecium

In vitro activity of BAL30072 against Burkholderia pseudomallei

Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli

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