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Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A

mAbs, 2020-01, Vol.12 (1), p.1770018

2020

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Repeated exposure of house dust mite induces progressive airway inflammation in mice: Differential roles of CCL17 and IL‐13

Pharmacology research & perspectives, 2021-05, Vol.9 (3), p.e00770-n/a

2021

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Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis

Journal of leukocyte biology, 2000-06, Vol.67 (6), p.841-846

2000

Volltextzugriff (PDF)

Mast cell modulation of immune responses to bacteria

Immunological reviews, 2001-02, Vol.179 (1), p.16-24

2001

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Role of Janus kinase-2 in IgE receptor-mediated leukotriene C4 production by mast cells

Biochemical and biophysical research communications, 2009-12, Vol.390 (3), p.786-790

2009

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The mast cell tumor necrosis factor α response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (14), p.8110-8115

1999

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Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4382-4386

2007

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Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic

Nature (London), 1997-10, Vol.389 (6651), p.636-639

1997

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Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice

European journal of pharmacology, 2006-06, Vol.539 (3), p.195-204

2006

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Targeting Janus Kinase 3 in Mast Cells Prevents Immediate Hypersensitivity Reactions and Anaphylaxis

The Journal of biological chemistry, 1999-09, Vol.274 (38), p.27028-27038

1999

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Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97)

The Journal of pharmacology and experimental therapeutics, 2000-12, Vol.295 (3), p.912

2000

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Development of a murine intestinal explant model to examine immune mechanisms of graft versus host disease

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.55-55.46

2018

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Cytotoxic T lymphocyte antigen‐4 regulates development of xenogenic graft versus host disease in mice via modulation of host immune responses induced by changes in human T cell engraftment and gene expression

Clinical and experimental immunology, 2021-12, Vol.206 (3), p.422-438

2021

Volltextzugriff (PDF)

Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice

The Journal of immunology (1950), 2019-04, Vol.202 (7), p.2017-2026

2019

Volltextzugriff (PDF)

Reversible translocation of 5-lipoxygenase in mast cells upon IgE/antigen stimulation

The Journal of biological chemistry, 1993-03, Vol.268 (7), p.4939-4944

1993

Volltextzugriff (PDF)

Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.2915-2929

2020

Volltextzugriff (PDF)

Combined Blockade of TNFα and IL-17A Ameliorates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice

The Journal of immunology (1950), 2019-02, Vol.202 (7), p.2017-2026

2019

Volltextzugriff (PDF)

Janus kinase-3 dependent inflammatory responses in allergic asthma

International immunopharmacology, 2010-08, Vol.10 (8), p.829-836

2010

Volltextzugriff (PDF)

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

Nature (London), 1996-05, Vol.381 (6577), p.77-80

1996

Volltextzugriff (PDF)

Role of Janus kinase-2 in IgE receptor-mediated leukotriene C 4 production by mast cells

Biochemical and biophysical research communications, 2009-12, Vol.390 (3), p.786-790

2009

Volltextzugriff (PDF)

Different approaches to study mast cell functions

International immunopharmacology, 2007-05, Vol.7 (5), p.555-567

2007

Volltextzugriff (PDF)

CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation

Drug metabolism and disposition, 2002-01, Vol.30 (1), p.74

2002

Volltextzugriff (PDF)

Simplified staurosporine analogs as potent JAK3 inhibitors

Bioorganic & medicinal chemistry letters, 2007-01, Vol.17 (2), p.326-331

2007

Volltextzugriff (PDF)

Regulation of mast cell-mediated innate immunity during early response to bacterial infection

Clinical reviews in allergy & immunology, 2002-04, Vol.22 (2), p.189-204

2002

Volltextzugriff (PDF)

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Characterization of concurrent target suppression by JNJ-61178104, a bispecific antibody against human tumor necrosis factor and interleukin-17A

Repeated exposure of house dust mite induces progressive airway inflammation in mice: Differential roles of CCL17 and IL‐13

Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis

Mast cell modulation of immune responses to bacteria

Role of Janus kinase-2 in IgE receptor-mediated leukotriene C4 production by mast cells

The mast cell tumor necrosis factor α response to FimH-expressing Escherichia coli is mediated by the glycosylphosphatidylinositol-anchored molecule CD48

Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma

Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid traffic

Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice

Targeting Janus Kinase 3 in Mast Cells Prevents Immediate Hypersensitivity Reactions and Anaphylaxis

Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97)

Development of a murine intestinal explant model to examine immune mechanisms of graft versus host disease

Cytotoxic T lymphocyte antigen‐4 regulates development of xenogenic graft versus host disease in mice via modulation of host immune responses induced by changes in human T cell engraftment and gene expression

Combined Blockade of TNF-α and IL-17A Alleviates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice

Reversible translocation of 5-lipoxygenase in mast cells upon IgE/antigen stimulation

Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease

Combined Blockade of TNFα and IL-17A Ameliorates Progression of Collagen-Induced Arthritis without Causing Serious Infections in Mice

Janus kinase-3 dependent inflammatory responses in allergic asthma

PD-L1- and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease

Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-α

Role of Janus kinase-2 in IgE receptor-mediated leukotriene C 4 production by mast cells

Different approaches to study mast cell functions

CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation

Simplified staurosporine analogs as potent JAK3 inhibitors

Regulation of mast cell-mediated innate immunity during early response to bacterial infection

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