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Cancer immunotherapy and breaking immune tolerance: new approaches to an old challenge

Cancer research (Chicago, Ill.), 2015-01, Vol.75 (1), p.5-10

2015

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Rationale for anti-CD137 cancer immunotherapy

European journal of cancer (1990), 2016-02, Vol.54, p.112-119

2016

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Macrophages as Cell-Based Delivery Systems for Nanoshells in Photothermal Therapy

Annals of biomedical engineering, 2012-02, Vol.40 (2), p.507-515

2012

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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

Journal for immunotherapy of cancer, 2017-12, Vol.5 (1), p.101-101, Article 101

2017

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Re-Evaluating the Effects of Obesity on Cancer Immunotherapy Outcomes in Renal Cancer: What Do We Really Know?

Frontiers in immunology, 2021-08, Vol.12, p.668494-668494

2021

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Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models

Clinical & translational immunology, 2022, Vol.11 (2), p.e1373-n/a

2022

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Obesity diminishes response to PD-1-based immunotherapies in renal cancer

Journal for immunotherapy of cancer, 2020-12, Vol.8 (2), p.e000725

2020

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Three Steps to Breaking Immune Tolerance: A Microparticle Approach

Blood, 2014-12, Vol.124 (21), p.4504-4504

2014

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Photothermal treatment of glioma; an in vitro study of macrophage-mediated delivery of gold nanoshells

Journal of neuro-oncology, 2011-09, Vol.104 (2), p.439-448

2011

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Off-the-shelf Vδ1 gamma delta T cells engineered with glypican-3 (GPC-3)-specific chimeric antigen receptor (CAR) and soluble IL-15 display robust antitumor efficacy against hepatocellular carcinoma

Journal for immunotherapy of cancer, 2021-12, Vol.9 (12), p.e003441

2021

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Allogeneic Vδ1 gamma delta T cells engineered with glypican-3 (GPC3)-specific CAR expressing soluble IL-15 have enhanced antitumor efficacy against hepatocellular carcinoma in preclinical models

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.e14511-e14511

2021

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Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity

Journal of medicinal chemistry, 2023-01, Vol.66 (1), p.345-370

2023

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Biodegradable Microparticles Loaded with Doxorubicin and CpG ODN for In Situ Immunization Against Cancer

The AAPS journal, 2015-01, Vol.17 (1), p.184-193

2015

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Abstract 3509: The glutaminase inhibitor CB-839 synergizes with CDK4/6 and PARP inhibitors in pre-clinical tumor models

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3509-3509

2018

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Overcoming obesity-induced immunotherapeutic failure

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.181-181.15

2018

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Abstract 2318: Discovery and validation of a novel checkpoint target preferentially expressed in the tumor microenvironment

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2318-2318

2016

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Abstract 4134: Reversal of adenosine-mediated immune suppression by CB-708, an orally bioavailable and potent small molecule inhibitor of CD73

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4134-4134

2019

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The potential use of toll-like receptor (TLR) agonists and antagonists as prophylactic and/or therapeutic agents

Immunopharmacology and immunotoxicology, 2009-09, Vol.31 (3), p.331-338

2009

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Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

Oncoimmunology, 2016-07, Vol.5 (7), p.e1192740-e1192740

2016

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Abstract A042: A predictive nomogram to determine CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy

Cancer immunology research, 2016-01, Vol.4 (1_Supplement), p.A042-A042

2016

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Three steps to breaking immune tolerance to lymphoma: a microparticle approach

Cancer immunology research, 2015-04, Vol.3 (4), p.389-398

2015

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Abstract B045: Arginase inhibitor CB-1158 elicits immune-mediated antitumor responses as a single agent and in combination with other immunotherapies

Cancer immunology research, 2016-11, Vol.4 (11_Supplement), p.B045-B045

2016

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Predicting CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy

Journal for immunotherapy of cancer, 2015-11, Vol.3 (Suppl 2), p.P98-P98

2015

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Biodegradable microparticles for in situ immunization against cancer

Makkouk, Amani Riad

2014

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ProQuest

Macrophages loaded with gold nanoshells for photothermal ablation of glioma: An in vitro model

Makkouk, Amani Riad

2010

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ProQuest

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Cancer immunotherapy and breaking immune tolerance: new approaches to an old challenge

Rationale for anti-CD137 cancer immunotherapy

Macrophages as Cell-Based Delivery Systems for Nanoshells in Photothermal Therapy

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

Re-Evaluating the Effects of Obesity on Cancer Immunotherapy Outcomes in Renal Cancer: What Do We Really Know?

Allogeneic CD20‐targeted γδ T cells exhibit innate and adaptive antitumor activities in preclinical B‐cell lymphoma models

Obesity diminishes response to PD-1-based immunotherapies in renal cancer

Three Steps to Breaking Immune Tolerance: A Microparticle Approach

Photothermal treatment of glioma; an in vitro study of macrophage-mediated delivery of gold nanoshells

Off-the-shelf Vδ1 gamma delta T cells engineered with glypican-3 (GPC-3)-specific chimeric antigen receptor (CAR) and soluble IL-15 display robust antitumor efficacy against hepatocellular carcinoma

Allogeneic Vδ1 gamma delta T cells engineered with glypican-3 (GPC3)-specific CAR expressing soluble IL-15 have enhanced antitumor efficacy against hepatocellular carcinoma in preclinical models

Discovery of a Series of Potent, Selective, and Orally Bioavailable Nucleoside Inhibitors of CD73 That Demonstrates In Vivo Antitumor Activity

Biodegradable Microparticles Loaded with Doxorubicin and CpG ODN for In Situ Immunization Against Cancer

Abstract 3509: The glutaminase inhibitor CB-839 synergizes with CDK4/6 and PARP inhibitors in pre-clinical tumor models

Overcoming obesity-induced immunotherapeutic failure

Abstract 2318: Discovery and validation of a novel checkpoint target preferentially expressed in the tumor microenvironment

Abstract 4134: Reversal of adenosine-mediated immune suppression by CB-708, an orally bioavailable and potent small molecule inhibitor of CD73

The potential use of toll-like receptor (TLR) agonists and antagonists as prophylactic and/or therapeutic agents

Anti-CD137 enhances anti-CD20 therapy of systemic B-cell lymphoma with altered immune homeostasis but negligible toxicity

Abstract A042: A predictive nomogram to determine CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy

Three steps to breaking immune tolerance to lymphoma: a microparticle approach

Abstract B045: Arginase inhibitor CB-1158 elicits immune-mediated antitumor responses as a single agent and in combination with other immunotherapies

Predicting CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy

Biodegradable microparticles for in situ immunization against cancer

Macrophages loaded with gold nanoshells for photothermal ablation of glioma: An in vitro model

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