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Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8807

2022

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Insight into the Biological Roles and Mechanisms of Phytochemicals in Different Types of Cancer: Targeting Cancer Therapeutics

Nutrients, 2023-03, Vol.15 (7), p.1704

2023

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Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2224944-2224944

2023

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2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling

European journal of medicinal chemistry, 2023-10, Vol.258, p.115610-115610, Article 115610

2023

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In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2

PloS one, 2024-04, Vol.19 (4), p.e0301086-e0301086

2024

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Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2201407-2201407

2023

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Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain

Biomedicine & pharmacotherapy, 2023-11, Vol.167, p.115596-115596, Article 115596

2023

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Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities

Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2292482-2292482

2024

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Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2199950

2023

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DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-Ras

PloS one, 2024-03, Vol.19 (3), p.e0300035-e0300035

2024

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A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico investigations

Journal of enzyme inhibition and medicinal chemistry, 2024-12, Vol.39 (1), p.2293639-2293639

2024

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Exploring natural compound, Panicutine as leucine-rich repeat kinase 2 inhibitor against Parkinson’s disease: a structure-guided approach

Journal of biomolecular structure & dynamics, 2023-10, p.1-10

2023

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Biological evaluation, docking studies, and in silico ADME prediction of some pyrimidine and pyridine derivatives as potential EGFRWT and EGFRT790M inhibitors

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.176-191

2023

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WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2185761-2185761

2023

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Influence of solvent selection and extraction methods on the determination of polyphenols, antioxidant, lipoxygenase and tyrosinase inhibition activities of Opuntia ficus-indica fruits peel and pulp collected from the Kingdom of Saudi Arabia (KSA)

Natural product research, 2023-02, Vol.37 (3), p.514-521

2023

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Correction: Identifying β-secretase 1 (BACE1) inhibitors from plant-based compounds: an approach targeting Alzheimer's therapeutics employing molecular docking and dynamics simulation

Molecular diversity, 2024-03

2024

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An updated review of fatty acid residue-tethered heterocyclic compounds: synthetic strategies and biological significance

RSC advances, 2023-05, Vol.13 (2), p.13655-13682

2023

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Unveiling Phytoconstituents with Inhibitory Potential Against Tyrosine-Protein Kinase Fyn: A Comprehensive Virtual Screening Approach Targeting Alzheimer's Disease

Journal of Alzheimer's disease, 2023-01, Vol.96 (2), p.827-844

2023

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A phenylpropanoid dimer from the leaves of Piper betle

Natural product research, 2023-05, Vol.37 (9), p.1550-1556

2023

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Isoquinoline alkaloids from Asimina triloba

Natural product research, 2019-10, Vol.33 (19), p.2823-2829

2019

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Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study

Bioorganic chemistry, 2024-02, Vol.143, p.107009-107009, Article 107009

2024

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Phytochemical profiling and mechanistic evaluation of black garlic extract on multiple sclerosis rat model

Journal of functional foods, 2023-12, Vol.111, p.105900, Article 105900

2023

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The value of Genus Acacia in arid and semi-arid environments for the treatment of chronic inflammatory diseases

Phytomedicine Plus : International journal of phytotherapy and phytopharmacology, 2022-08, Vol.2 (3), p.100315, Article 100315

2022

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DFT and molecular simulation validation of the binding activity of PDE[delta] inhibitors for repression of oncogenic k-Ras

PloS one, 2024-03, Vol.19 (3)

2024

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Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant IMycobacterium tuberculosis/I

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24)

2022

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Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant Mycobacterium tuberculosis

Insight into the Biological Roles and Mechanisms of Phytochemicals in Different Types of Cancer: Targeting Cancer Therapeutics

Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt

2,4-Diaryl-pyrimido[1,2-a]benzimidazole derivatives as novel anticancer agents endowed with potent anti-leukemia activity: Synthesis, biological evaluation and kinase profiling

In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights

Phytochemical profiling and neuroprotective activity of Callistemon subulatus leaves against cyclophosphamide-induced chemobrain

Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities

Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia

DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-Ras

A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico investigations

Exploring natural compound, Panicutine as leucine-rich repeat kinase 2 inhibitor against Parkinson’s disease: a structure-guided approach

Biological evaluation, docking studies, and in silico ADME prediction of some pyrimidine and pyridine derivatives as potential EGFRWT and EGFRT790M inhibitors

WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway

Influence of solvent selection and extraction methods on the determination of polyphenols, antioxidant, lipoxygenase and tyrosinase inhibition activities of Opuntia ficus-indica fruits peel and pulp collected from the Kingdom of Saudi Arabia (KSA)

Correction: Identifying β-secretase 1 (BACE1) inhibitors from plant-based compounds: an approach targeting Alzheimer's therapeutics employing molecular docking and dynamics simulation

An updated review of fatty acid residue-tethered heterocyclic compounds: synthetic strategies and biological significance

Unveiling Phytoconstituents with Inhibitory Potential Against Tyrosine-Protein Kinase Fyn: A Comprehensive Virtual Screening Approach Targeting Alzheimer's Disease

A phenylpropanoid dimer from the leaves of Piper betle

Isoquinoline alkaloids from Asimina triloba

Novel indolinone-tethered benzothiophenes as anti-tubercular agents against MDR/XDR M. tuberculosis: Design, synthesis, biological evaluation and in vivo pharmacokinetic study

Phytochemical profiling and mechanistic evaluation of black garlic extract on multiple sclerosis rat model

The value of Genus Acacia in arid and semi-arid environments for the treatment of chronic inflammatory diseases

DFT and molecular simulation validation of the binding activity of PDE[delta] inhibitors for repression of oncogenic k-Ras

Development of Novel Isatin-Tethered Quinolines as Anti-Tubercular Agents against Multi and Extensively Drug-Resistant IMycobacterium tuberculosis/I

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