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Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures

Chemical communications (Cambridge, England), 2018, Vol.54 (15), p.1897-1900

2018

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Cell Senescence and Telomere Shortening Induced by a New Series of Specific G-Quadruplex DNA Ligands

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2672-2677

2002

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Natural and pharmacological regulation of telomerase

Nucleic acids research, 2002-02, Vol.30 (4), p.839-865

2002

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N-Heterocyclic Carbene-Amine Pt(II) Complexes, a New Chemical Space for the Development of Platinum-Based Anticancer Drugs

Journal of medicinal chemistry, 2010-03, Vol.53 (5), p.2146-2154

2010

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Synthesis of Oxa-Bridged Analogues of Farnesyltransferase Inhibitor RPR 115135

Journal of organic chemistry, 2001-06, Vol.66 (11), p.3797-3805

2001

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Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands

Oncogene, 2005-04, Vol.24 (18), p.2917-2928

2005

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Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase

Biochemical and biophysical research communications, 2004-10, Vol.323 (3), p.802-808

2004

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Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structuresElectronic supplementary information (ESI) available. See DOI: 10.1039/c7cc07048a

2018-02

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Preferential binding of a G-quadruplex ligand to human chromosome ends

Nucleic acids research, 2005-01, Vol.33 (13), p.4182-4190

2005

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Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing

Nucleic acids research, 2004-01, Vol.32 (1), p.371-379

2004

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Selective Interaction of Ethidium Derivatives with Quadruplexes: An Equilibrium Dialysis and Electrospray Ionization Mass Spectrometry Analysis

Biochemistry (Easton), 2003-09, Vol.42 (35), p.10361-10371

2003

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Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes

Nucleic acids research, 2001-03, Vol.29 (5), p.1087-1096

2001

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Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration

The Journal of biological chemistry, 2003-12, Vol.278 (50), p.50554-50562

2003

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Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence

Nucleic acids research, 2005-01, Vol.33 (7), p.2192-2203

2005

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1,3-Dipolar cycloaddition route to novel isoxazole-type derivatives related to combretastatin A-4

Tetrahedron letters, 2004-04, Vol.45 (17), p.3359-3362

2004

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RPR 130401, a Nonpeptidomimetic Farnesyltransferase Inhibitor with in Vivo Activity

Annals of the New York Academy of Sciences, 1999-01, Vol.886 (1), p.249-251

1999

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Diastereoselective Syntheses of New Analogues of the Farnesyltransferase Inhibitor RPR 130401

Journal of organic chemistry, 2004-10, Vol.69 (21), p.7220-7227

2004

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Telomerase: a therapeutic target for the third millennium?

Critical reviews in oncology/hematology, 2000-05, Vol.34 (2), p.111-126

2000

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Inhibiteurs de la télomérase : conséquences pour la thérapeutique anticancéreuse

M.S. Médecine sciences, 2001, Vol.17 (10), p.1076

2001

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Multivariate Data Analysis Using D-Optimal Designs, Partial Least Squares, and Response Surface Modeling: A Directional Approach for the Analysis of Farnesyltransferase Inhibitors

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1807-1816

2000

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A Diastereoselective Switch in the Access to Isobenzofuran-Derived α-Selenoesters

Organic letters, 2000-04, Vol.2 (7), p.923-925

2000

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Targeting human telomerase for cancer therapeutics

Cytotechnology (Dordrecht), 2004-06, Vol.45 (1-2), p.75-90

2004

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Ligand binding to tetra-end-linked (TGGGGT)4 G-quadruplexes: an electrospray mass spectroscopy study

Nucleic Acids Symposium Series, 2008, Vol.52 (1), p.165-166

2008

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The development of telomerase inhibitors: the G-quartet approach

Anti-cancer drug design, 1999-08, Vol.14 (4), p.327

1999

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Synthesis and biological evaluation of a series of hydroxybenzylphenylamine derivatives as inhibitors of EGF receptor-associated tyrosine kinase activity

Anti-cancer drug design, 1996-01, Vol.11 (1), p.49

1996

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Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures

Cell Senescence and Telomere Shortening Induced by a New Series of Specific G-Quadruplex DNA Ligands

Natural and pharmacological regulation of telomerase

N-Heterocyclic Carbene-Amine Pt(II) Complexes, a New Chemical Space for the Development of Platinum-Based Anticancer Drugs

Synthesis of Oxa-Bridged Analogues of Farnesyltransferase Inhibitor RPR 115135

Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands

Stabilization of the c-myc gene promoter quadruplex by specific ligands’ inhibitors of telomerase

Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structuresElectronic supplementary information (ESI) available. See DOI: 10.1039/c7cc07048a

Preferential binding of a G-quadruplex ligand to human chromosome ends

Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing

Selective Interaction of Ethidium Derivatives with Quadruplexes: An Equilibrium Dialysis and Electrospray Ionization Mass Spectrometry Analysis

Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes

Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration

Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence

1,3-Dipolar cycloaddition route to novel isoxazole-type derivatives related to combretastatin A-4

RPR 130401, a Nonpeptidomimetic Farnesyltransferase Inhibitor with in Vivo Activity

Diastereoselective Syntheses of New Analogues of the Farnesyltransferase Inhibitor RPR 130401

Telomerase: a therapeutic target for the third millennium?

Inhibiteurs de la télomérase : conséquences pour la thérapeutique anticancéreuse

Multivariate Data Analysis Using D-Optimal Designs, Partial Least Squares, and Response Surface Modeling: A Directional Approach for the Analysis of Farnesyltransferase Inhibitors

A Diastereoselective Switch in the Access to Isobenzofuran-Derived α-Selenoesters

Targeting human telomerase for cancer therapeutics

Ligand binding to tetra-end-linked (TGGGGT)4 G-quadruplexes: an electrospray mass spectroscopy study

The development of telomerase inhibitors: the G-quartet approach

Synthesis and biological evaluation of a series of hydroxybenzylphenylamine derivatives as inhibitors of EGF receptor-associated tyrosine kinase activity

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